RNA function follows form β why is it so hard to predict?
AlphaFoldβs highly accurate structural models transformed protein biology,but RNA lags behind.
AlphaFoldβs highly accurate structural models transformed protein biology. Nature reports on the efforts to create a similar system for RNA and why itβs a tougher nut to crack. #RNAsky π§ͺ
30.03.2025 13:36
π 70
π 20
π¬ 0
π 2
If you're interested, you can read more about Lane-Claypon β and the origins of other crucial methods for separating truth from fiction - in my new book Proof: proof.kucharski.io
29.03.2025 07:13
π 113
π 12
π¬ 5
π 1
Excited to see our work published! πͺ°π₯¬ Really happy I got to contribute to this projectβ huge thanks to @nmvandam.bsky.social and @axeltouw.bsky.social for everything I learned through this!
29.03.2025 09:03
π 4
π 0
π¬ 1
π 0
GitHub - yangao07/longcallD: A local-haplotagging-based small and structural variant caller
A local-haplotagging-based small and structural variant caller - yangao07/longcallD
longcallD is a new variant caller for genomic long reads. It jointly calls phased small and structural variants. Single binary, one command line for the whole process. Comparable accuracy to mainstream callers. Great work by Yan Gao. github.com/yangao07/lon...
24.03.2025 16:53
π 105
π 49
π¬ 3
π 3
In every civilization, people end up sorted into levels of socio-economic status (SES). We explore the history, present, and future of scientific research on the complicated relationship between SES and DNA in @naturehumbehav.bsky.socialπ°π§¬π
Link: rdcu.be/efacK
Thread below ππ½
26.03.2025 11:15
π 229
π 83
π¬ 6
π 18
Glaciers are not just blocks of ice β plans to save them mustnβt overlook their hidden life
As glaciers begin to disappear, technological fixes to slow or halt ice melt are emerging. But regulations are urgently required before these fixes are used widely.
There is remarkably little consensus on how to save a glacier. Technological interventions are starting to be explored but they are controversial and itβs unclear that they would protect life in the ecosystem that is meant to be savedβ¦
π§ͺ
@nature.com
www.nature.com/articles/d41...
25.03.2025 07:22
π 9
π 3
π¬ 0
π 0
Branching from the wild mustard (Brassica oleracea) based on selection for stem (Kohlrabi), leaves (Kale), terminal leaf buds (Cabbage), flower buds (Cauliflower), flowerbud+stem (Broccoli), and terrible life choices (Brussel Sprouts).
The many forms of Brassica Oleracea are definitely a testament to humans' tendency to engineer and change things around them to fit their preferences.
Also, that some people should not have a say about what's for dinner. π§ͺ
pmc.ncbi.nlm.nih.gov/articles/PMC...
25.03.2025 07:30
π 55
π 14
π¬ 2
π 3
Opinion | Why Did Elon Musk Go After Bunkers Full of Seeds? (Gift Article)
Gene banks are like a survivalist cache: our nationβs safeguard against all future challenges to growing the food we need.
The genetic heritage of our food system is conserved by US federal employees who are at risk of losing their ability to protect collections of plants and germplasm we require as we face the triple threat of crop disease, climate change, and species extinction. π§ͺ π π±
www.nytimes.com/2025/03/22/o...
22.03.2025 18:51
π 168
π 95
π¬ 3
π 10
Macroecological rules predict how biomass scales with species richness in nature
Despite advances in theory and experiments, how biodiversity influences the structure and functioning of natural ecosystems remains debated. By applying new theory to data on 84,695 plant, animal, and...
New ποΈled by Alex Pigot - Macroecological rules predict how biomass scales with species richness in nature -Standing biomass increases with richness when large-bodied spp are numerically rare but independent when spp size & abundance are uncoupled. @ucl.ac.uk - Science www.science.org/doi/10.1126/...
21.03.2025 09:27
π 70
π 34
π¬ 4
π 2
Cologne Spring Meeting continues with βResurrecting plants for climate change researchβ by Niek Scheepens from @unituebingen.bsky.social Innovating plant resurrection techniques to study climate adaptation. #ClimateChange #PlantResurrection #TRR341 #DFG
20.03.2025 08:53
π 13
π 4
π¬ 1
π 2
The @meauxjuliette.bsky.social lab review the latest evidence of how complex traits are underpinned by polygenic molecular traits
π doi.org/10.1093/pcp/...
One of the many excellent papers featuring in our forthcoming special issue on ' #plantecology & #evolution' - out soon!
#PlantScience
20.03.2025 15:14
π 11
π 3
π¬ 0
π 0