Group 4, Round 1 @uvaresearch.bsky.social @uvaimmunology.bsky.social
@jie-immunology
Harrison professor of medicine at UVA. We study respiratory immunity and immunopathology. Working on COVID, Influenza, Aging, T cells, macrophages, lung regeneration and tumorigenesis. https://www.immunology.virginia.edu/Sun/publications.php
Group 4, Round 1 @uvaresearch.bsky.social @uvaimmunology.bsky.social
We are excited that our paper on peroxisomal control of viral injury and long COVID @science is selected for the #STATMadnessย @statnews.com Small Organelle #Peroxisome Big Roles! Help us to go to round 2!๐ statnews.com/feature/stat-madness/bracket-voting-now-open
Very excited that this manuscript is โaccepted in principleโ today! Stay tuned for the final version of the manuscript soon ๐.
A distinct monocyte transcriptional state links systemic immune dysregulation to pulmonary impairment in long COVID @natimmunol.nature.com @saumkmr.bsky.social @ciim-hannover.bsky.social @jie-immunology.bsky.social
www.nature.com/articles/s41...
Temporal single-cell profiling uncovers age-associated delays in immune resolution to respiratory viral infection
@biorxivpreprint.bsky.social @jie-immunology.bsky.social
www.biorxiv.org/content/10.6...
CIC research has a global impact: @jie-immunology.bsky.social and his team appeared in a Tokyo Broadcasting System news segment on COVID-19 research and funding! www.youtube.com/watch?v=SYrb...
Couldnโt be prouder of this team! We are excited to welcome new members and celebrate big career milestones of lab colleagues!
TCF4 regulates alveolar macrophage stemness and is a promising therapeutic target in long COVID and related chronic lung diseases @jie-immunology.bsky.social @biorxivpreprint.bsky.social @uvaimmunology.bsky.social
www.biorxiv.org/content/10.1...
Jinyi Tang, PhD, received an NIHK99/R00 grant! The award was issued for Jinyi's work developing mucosal vaccines, which he and the @jie-immunology.bsky.social lab have shown to offer additional protection against COVID-19.
Read more: immunology.virginia.edu/jtang_k99/
Our data establish the causal link of respiratory viral infection with subsequent lung cancer development for the first time. This work highlights the urgent need to close monitor COVID-19 survivors for elevated lung cancer risk and develop targeted interventions.
Importantly, our study shows that vaccination can mitigate this enhanced cancer growth by preventing severe disease. This underscores the power of vaccines in preventing not only acute illness but also serious long-term consequences including lung cancer.
Mechanistically, we found that viral pneumonia epigenetically reprograms the lung, creating a pro-tumor environment driven by immunosuppressive neutrophils. These cells suppress anti-tumor immunity and are linked to poor survival in lung cancer patients.
Our clinical data shows that patients hospitalized with COVID-19 had a significantly higher risk of a new lung cancer diagnosis in the following years. This increased risk was not seen in overall cancer types.
Excited to share our new findings: Severe respiratory viral infections like COVID-19 and flu can accelerate lung cancer development. Our study establishes a direct causal link, highlighting the urgent need for long-term cancer surveillance in COVID-19 survivors.
doi.org/10.1101/2025...
HHS Secretary Robert F. Kennedy Jr. threatened to bar government scientists from publishing in major medical journals, saying on a podcast that three top journals were โcorruptโ and influenced by pharmaceutical companies.
SIS 2025 registration ends next Monday. We still have a few seats available. Please join us! @uvaimmunology.bsky.social
SIS 2025 early registration and abstract due today. Please join us! @uvaimmunology.bsky.social
Abstract submission due in 1 week on April. 21st. #SIS2025. Please join Drs. Merad, Mathis and Kipnis and many more on the beautiful UVA campus.
www.immunology.virginia.edu/sis2025/
Massive crowd at Hands Off rally in St. Paul, Minnesota
Wow. #HandsOff rally in St. Paul, Minnesota is massive!
How I will remember April Fools' Day 2025.
Reckless.
My heart is out for these dedicated folks at NIH, FDA and CDC
www.statnews.com/2025/04/01/h...
By attacking science:
We are less safe because science informs national security and medical care.
We are less prosperous because science drives innovation and economic benefit.
We are less free because science and democracy depend on the liberty to ask questions, and seek and share knowledge.
We are glad to make to the round of 16 #STATMadness2025. Our work has discovered an aberrant immune-epithelial niche underlying severe long COVID. www.nature.com/articles/s41...
Please keep supporting us by voting for the University of Virginia team.
Join us on the topic of an aberrant immune-epithelial niche driving respiratory long COVID at the ATS online journal club. Please register below here. site.thoracic.org/events/an-ab...
If any of this seems normal, you need to open your eyes.
profkap.substack.com/p/never-norm...
We are glad to make to the round of 16 #STATMadness2025. Our work has discovered an aberrant immune-epithelial niche underlying severe long COVID. www.nature.com/articles/s41...
Please keep supporting us by voting for the University of Virginia team.
Join us with Drs. Mathis, Kipnis and Merad for #SIS2025 at the beautiful UVA campus in Charlottesville! Itโs an affordable meeting with an outstanding speaker lineup. Enjoy the superb local history, food, wineries, events, and scenic views. immunology.virginia.edu/sis2025/
Five years ago on March 11, the World Health Organization officially declared COVID-19 a pandemic.
Our 100th episode is out! ๐
Nobel Laureate Dr. Peter Doherty (@pcdoherty.bsky.social) discusses his career, from studying sheep as a veterinarian to discovering the mechanisms of #Tcell antigen recognition. ๐
Listen now: bit.ly/3FxLX1X
To vote, please select the โUniversity of Virginiaโ team. We need your vote daily ๐ ๐.