's Avatar

@jie-immunology

Harrison professor of medicine at UVA. We study respiratory immunity and immunopathology. Working on COVID, Influenza, Aging, T cells, macrophages, lung regeneration and tumorigenesis. https://www.immunology.virginia.edu/Sun/publications.php

240
Followers
272
Following
25
Posts
11.12.2024
Joined
Posts Following

Latest posts by @jie-immunology

Post image

Group 4, Round 1 @uvaresearch.bsky.social @uvaimmunology.bsky.social

02.03.2026 12:07 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Preview
2026 STAT Madness 2026 bracket Welcome to STAT Madness, a bracket-style contest to find the best innovation in science and medicine. Explore groundbreaking innovations from

We are excited that our paper on peroxisomal control of viral injury and long COVID @science is selected for the #STATMadnessย  @statnews.com Small Organelle #Peroxisome Big Roles! Help us to go to round 2!๐Ÿ™ statnews.com/feature/stat-madness/bracket-voting-now-open

02.03.2026 12:06 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0

Very excited that this manuscript is โ€œaccepted in principleโ€ today! Stay tuned for the final version of the manuscript soon ๐Ÿ˜„.

22.01.2026 00:35 ๐Ÿ‘ 2 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 1
Post image

A distinct monocyte transcriptional state links systemic immune dysregulation to pulmonary impairment in long COVID @natimmunol.nature.com @saumkmr.bsky.social @ciim-hannover.bsky.social @jie-immunology.bsky.social
www.nature.com/articles/s41...

15.01.2026 01:48 ๐Ÿ‘ 4 ๐Ÿ” 2 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 2
Post image

Temporal single-cell profiling uncovers age-associated delays in immune resolution to respiratory viral infection
@biorxivpreprint.bsky.social @jie-immunology.bsky.social
www.biorxiv.org/content/10.6...

18.12.2025 03:32 ๐Ÿ‘ 6 ๐Ÿ” 2 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0
ใ€ใƒˆใƒฉใƒณใƒ—ๆ”ฟๆจฉใ€ŒๅŒป็™‚ไบˆ็ฎ—ๅ‰Šๆธ›ใ€ใ€‘โ€œๅ†ใณใ‚ขใƒกใƒชใ‚ซใ‚’ๅฅๅบทใซโ€ใชใฎใซ๏ผŸใ€€้›ฃ็—…ใฎๆฒป็™‚ๆณ•็ ”็ฉถใซใ‚‚ๅฝฑ้ŸฟใŒโ€ฆใ€€ๆ–ฐๅž‹ใ‚ณใƒญใƒŠๅพŒ้บ็—‡ๆ‚ฃ่€…ใซไธๅฎ‰๏ฝœTBSย NEWSย DIG
ใ€ใƒˆใƒฉใƒณใƒ—ๆ”ฟๆจฉใ€ŒๅŒป็™‚ไบˆ็ฎ—ๅ‰Šๆธ›ใ€ใ€‘โ€œๅ†ใณใ‚ขใƒกใƒชใ‚ซใ‚’ๅฅๅบทใซโ€ใชใฎใซ๏ผŸใ€€้›ฃ็—…ใฎๆฒป็™‚ๆณ•็ ”็ฉถใซใ‚‚ๅฝฑ้ŸฟใŒโ€ฆใ€€ๆ–ฐๅž‹ใ‚ณใƒญใƒŠๅพŒ้บ็—‡ๆ‚ฃ่€…ใซไธๅฎ‰๏ฝœTBSย NEWSย DIG YouTube video by TBS NEWS DIG Powered by JNN

CIC research has a global impact: @jie-immunology.bsky.social and his team appeared in a Tokyo Broadcasting System news segment on COVID-19 research and funding! www.youtube.com/watch?v=SYrb...

09.12.2025 19:50 ๐Ÿ‘ 1 ๐Ÿ” 1 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Post image

Couldnโ€™t be prouder of this team! We are excited to welcome new members and celebrate big career milestones of lab colleagues!

15.11.2025 16:22 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Post image

TCF4 regulates alveolar macrophage stemness and is a promising therapeutic target in long COVID and related chronic lung diseases @jie-immunology.bsky.social @biorxivpreprint.bsky.social @uvaimmunology.bsky.social
www.biorxiv.org/content/10.1...

07.10.2025 15:07 ๐Ÿ‘ 2 ๐Ÿ” 2 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Post image

Jinyi Tang, PhD, received an NIHK99/R00 grant! The award was issued for Jinyi's work developing mucosal vaccines, which he and the @jie-immunology.bsky.social lab have shown to offer additional protection against COVID-19.

Read more: immunology.virginia.edu/jtang_k99/

25.09.2025 19:03 ๐Ÿ‘ 4 ๐Ÿ” 2 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

Our data establish the causal link of respiratory viral infection with subsequent lung cancer development for the first time. This work highlights the urgent need to close monitor COVID-19 survivors for elevated lung cancer risk and develop targeted interventions.

04.09.2025 06:59 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

Importantly, our study shows that vaccination can mitigate this enhanced cancer growth by preventing severe disease. This underscores the power of vaccines in preventing not only acute illness but also serious long-term consequences including lung cancer.

04.09.2025 06:58 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0

Mechanistically, we found that viral pneumonia epigenetically reprograms the lung, creating a pro-tumor environment driven by immunosuppressive neutrophils. These cells suppress anti-tumor immunity and are linked to poor survival in lung cancer patients.

04.09.2025 06:57 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0

Our clinical data shows that patients hospitalized with COVID-19 had a significantly higher risk of a new lung cancer diagnosis in the following years. This increased risk was not seen in overall cancer types.

04.09.2025 06:55 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0
Preview
Respiratory viral infections prime accelerated lung cancer growth The COVID-19 pandemic has highlighted long-term health concerns of viral pneumonia, yet its potential impact on cancer development and growth remains poorly understood. Here, we demonstrate that prior...

Excited to share our new findings: Severe respiratory viral infections like COVID-19 and flu can accelerate lung cancer development. Our study establishes a direct causal link, highlighting the urgent need for long-term cancer surveillance in COVID-19 survivors.

doi.org/10.1101/2025...

04.09.2025 06:54 ๐Ÿ‘ 4 ๐Ÿ” 3 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 1
Preview
RFK Jr. threatens to bar government scientists from publishing in leading medical journals The health secretary said the New England Journal of Medicine, the Journal of the American Medical Association, and The Lancet are in bed with pharma.

HHS Secretary Robert F. Kennedy Jr. threatened to bar government scientists from publishing in major medical journals, saying on a podcast that three top journals were โ€œcorruptโ€ and influenced by pharmaceutical companies.

27.05.2025 19:24 ๐Ÿ‘ 5913 ๐Ÿ” 2259 ๐Ÿ’ฌ 1086 ๐Ÿ“Œ 486

SIS 2025 registration ends next Monday. We still have a few seats available. Please join us! @uvaimmunology.bsky.social

03.05.2025 21:02 ๐Ÿ‘ 4 ๐Ÿ” 3 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

SIS 2025 early registration and abstract due today. Please join us! @uvaimmunology.bsky.social

21.04.2025 15:23 ๐Ÿ‘ 3 ๐Ÿ” 1 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Post image

Abstract submission due in 1 week on April. 21st. #SIS2025. Please join Drs. Merad, Mathis and Kipnis and many more on the beautiful UVA campus.

www.immunology.virginia.edu/sis2025/

15.04.2025 11:41 ๐Ÿ‘ 5 ๐Ÿ” 1 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 2
Massive crowd at Hands Off rally in St. Paul, Minnesota

Massive crowd at Hands Off rally in St. Paul, Minnesota

Wow. #HandsOff rally in St. Paul, Minnesota is massive!

05.04.2025 20:08 ๐Ÿ‘ 53040 ๐Ÿ” 9996 ๐Ÿ’ฌ 579 ๐Ÿ“Œ 479
Preview
HHS starts layoffs of thousands of workers across its agencies Layoff notices began arriving early Tuesday for thousands of employees of HHS and its subsidiary agencies, with as many 10,000 workers potentially expected to be hit by the cuts.

How I will remember April Fools' Day 2025.
Reckless.
My heart is out for these dedicated folks at NIH, FDA and CDC
www.statnews.com/2025/04/01/h...

01.04.2025 14:44 ๐Ÿ‘ 975 ๐Ÿ” 247 ๐Ÿ’ฌ 27 ๐Ÿ“Œ 10

By attacking science:

We are less safe because science informs national security and medical care.

We are less prosperous because science drives innovation and economic benefit.

We are less free because science and democracy depend on the liberty to ask questions, and seek and share knowledge.

19.03.2025 14:21 ๐Ÿ‘ 1473 ๐Ÿ” 414 ๐Ÿ’ฌ 24 ๐Ÿ“Œ 13

We are glad to make to the round of 16 #STATMadness2025. Our work has discovered an aberrant immune-epithelial niche underlying severe long COVID. www.nature.com/articles/s41...
Please keep supporting us by voting for the University of Virginia team.

17.03.2025 10:52 ๐Ÿ‘ 3 ๐Ÿ” 1 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Preview
American Thoracic Society | An Aberrant Immuneโ€“Epithelial Progenitorโ€ฆ The American Thoracic Society is the world's leading medical society dedicated to accelerating the advancement of global respiratory health throughโ€ฆ

Join us on the topic of an aberrant immune-epithelial niche driving respiratory long COVID at the ATS online journal club. Please register below here. site.thoracic.org/events/an-ab...

20.03.2025 00:59 ๐Ÿ‘ 2 ๐Ÿ” 2 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Preview
Never normalize insanity I thought I was going to be writing this Substack to satirize the insanity and the maddening bureaucracy of academia.

If any of this seems normal, you need to open your eyes.

profkap.substack.com/p/never-norm...

17.03.2025 22:31 ๐Ÿ‘ 9 ๐Ÿ” 2 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

We are glad to make to the round of 16 #STATMadness2025. Our work has discovered an aberrant immune-epithelial niche underlying severe long COVID. www.nature.com/articles/s41...
Please keep supporting us by voting for the University of Virginia team.

17.03.2025 10:52 ๐Ÿ‘ 3 ๐Ÿ” 1 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Post image

Join us with Drs. Mathis, Kipnis and Merad for #SIS2025 at the beautiful UVA campus in Charlottesville! Itโ€™s an affordable meeting with an outstanding speaker lineup. Enjoy the superb local history, food, wineries, events, and scenic views. immunology.virginia.edu/sis2025/

16.03.2025 15:43 ๐Ÿ‘ 8 ๐Ÿ” 3 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Preview
UVA Health talks new discovery on COVID-19 anniversary Five years ago on March 11, the World Health Organization officially declared COVID-19 a pandemic.

Five years ago on March 11, the World Health Organization officially declared COVID-19 a pandemic.

11.03.2025 23:00 ๐Ÿ‘ 2 ๐Ÿ” 1 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Video thumbnail

Our 100th episode is out! ๐ŸŽŠ

Nobel Laureate Dr. Peter Doherty (@pcdoherty.bsky.social) discusses his career, from studying sheep as a veterinarian to discovering the mechanisms of #Tcell antigen recognition. ๐Ÿ‘

Listen now: bit.ly/3FxLX1X

12.03.2025 01:16 ๐Ÿ‘ 6 ๐Ÿ” 2 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 1

To vote, please select the โ€œUniversity of Virginiaโ€ team. We need your vote daily ๐Ÿ˜Š ๐Ÿ™.

10.03.2025 16:23 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0