Very excited to see this work out today!
Discovering viral immune antagonists directly from predicted protein structures. 🤩 www.science.org/doi/10.1126/...
Huge thanks to the amazing collaborators! 🤗
Amazing resolution of this beautiful mechanism!
@spp2330.bsky.social
🚨Preprint! Happy to share the research from my PhD “Genome delivery of a contractile tailed phage and its superinfection exclusion mechanism”. We use cryoEM to study the genome ejection of the phage T4, revealing how the tape measure protein regulates the process.
www.biorxiv.org/content/10.6...
Welcome to our new colleague Johannes Rebelein, head of the Institut of Sustainable Biotechnology @hhu.de and our new colleague at the Institute of Bio- and Geosciences 1 @fz-juelich.de.
Welcome to @mibinet.bsky.social!
www.chemie.hhu.de/en/latest-ne...
Fantastic collaboration w/ @dbikard.bsky.social @audeber.bsky.social @rayanchikhi.bsky.social labs led by @jmouradesousa.bsky.social : We assessed the rates of variation of anti-phage systems in P4-like satellites and P2 helper phages. Quick conclusion: Huge variation! We focus on 4 key questions/5
Save the date for the next International Conference on Gram-Positive Bacteria which will take place between 29 June–2 July 2027. The organizers (@annadragos.bsky.social, @polonca32.bsky.social, and Ines Mandic-Mulec) look forward to welcoming you to Ljubljana, Slovenia
@spp2330.bsky.social
New post-doctoral research position in my phage-host interactions (Phi) laboratory in @otagomicroimmuno.bsky.social at @universityofotago.bsky.social New Zealand. The project is focused on defences against jumbo phages. Please share and if interested apply using the link in the comments.
Join us as Assistant/Associate/Full Professor Computational Biology at Institute of Biology Leiden (IBL) / @leidenscience.bsky.social / @unileiden.bsky.social
Application deadline on 15 March 2026
👇
careers.universiteitleiden.nl/job/Assistan...
Cell death is a fundamental mechanism of antiviral immunity across diverse organisms, including bacteria. As my final PhD project with @jbdsf.bsky.social, I was curious whether cell death is required for successful immunity with the ancient cGAS pathway known as ‘CBASS.’
Spoiler – the answer is no!
Glückwunsch Lena!
Please RT:
Looking forward to our International Symposium on "Microbial Networking - from organelles to cross-kingdom communities".
Highlight of our first funding period of our Collaborative Researc Center @mibinet.bsky.social, @dfg.de
www.sfb1535.hhu.de/mibinet
@hhu.de , @fz-juelich.de
Lasse presents our CRC1535 MibiNet project at the first RNA confluence meeting at the EMBL.
@rhinelandrna.bsky.social @mibinet.bsky.social
Great opportunity to join the lab of @patrick-pausch.bsky.social !
www.linkedin.com/feed/update/...
Save the date, please RT:
Looking forward to an exciting International Symposium @spp2330.bsky.social "New concepts in prokaryotic virus-host interactions".
October 5-7, 2026; Harnack-Haus Berlin (Germany).
@dfg.de @hhu.de @fz-juelich.de
Congratulations! Nice to see this published!
We Are very happy that our Paper was published. Thank to everyone involved
pubs.acs.org/doi/10.1021/...
@mibinet.bsky.social @mfeldbruegge.bsky.social @frunzkelab.bsky.social
Great collaboration with @hoeferlab.bsky.social, @aharms485.bsky.social, @pozhydaieva.bsky.social, @usadellab.bsky.social, @vivienrosenthal.bsky.social
This shows that "abortive infection" phenotypes are not neccessarily in all cases a "last line" of defense, but may be the consequence of mechanisms interferring with early steps in the phage life cycle.
We further show synergy of daunorubicin with RM systems targeting the FST region T5 phages.
Happy to share our recent preprint:
"DNA-intercalating antiphage molecules trigger abortive infection through mutual destruction and synergize with bacterial immunity"
www.biorxiv.org/content/10.6...
@spp2330.bsky.social, @mibinet.bsky.social, @dfg.de @hhu.de @fzj.bsky.social
📢Postdoc position available!🧪🧫🧬
Our group is seeking a motivated researcher to investigate the molecular mechanisms driving host–endosymbiont interactions.
Full details & application: karriere.hhu.de//index.php?a....
Please help us get the word out!
Very happy to See This Published!!!! Thanks for the collaboration
link.springer.com/article/10.1...
www.biorxiv.org/content/10.1...
@soreklab.bsky.social Sorek lab does it again! Such a cool signal to specifically detect the event of genome degradation by a phage
Very nice to meet @heermann-lab.bsky.social and @gebhardlab.bsky.social in Mainz! Thank you for the warm welcome!
Another fantastic SPP 2330 meeting! Thank you all for three inspiring days of science, collaboration, and novel ideas. See you next year at our international symposium in Berlin, October 5–7, 2026! @dfg.de @fz-juelich.de @hhu.de
That was a phagetastic @spp2330.bsky.social meeting again! Thanks to everyone to your excellent presentations. Keep the spirit ☺️
@dfg.de
Already looking forward to our International Symposium in Berlin next year (October 5-7, 2026; Harnack-Haus)
Please RT:
We have an opening for a junior group leader position in „Phage Biology & Biotechnology“.
www.fz-juelich.de/de/karriere/...
Interested candidates are encouraged to contact me via email for further details.
@spp2330.bsky.social; @mibinet.bsky.social
Video compilation from our #türenauf mit der Maus Tag today! #outreach #chemsky @hhu.de @sophieguti.bsky.social @joguti.bsky.social @markussuta.bsky.social @chemiehhu.bsky.social
Just returning from a fantastic symposium celebrating my former postdoc mentor, Julia Vorholt, on receiving the Novonesis Biotechnology Prize! Huge congratulations to Julia — and to the Novo Nordisk Foundation on an outstanding choice!
New tenure track assistant professor position in molecular microbiology in our department @dmf-unil.bsky.social @unil.bsky.social! We are casting a wide net for an experimental molecular microbiologist. Apply here: wwwfbm.unil.ch/releve/appli...
