Alessandro Bartolomucci Lab's Avatar

Alessandro Bartolomucci Lab

@bartolomuccilab

Scientist interested in stress physiology, aging biology, social determinants of health, adipose tissue, sympathetic nervous system, metabolic diseases and much more. Professor at Univ. of Minnesota and Univ. of Parma https://bartolomuccilab.umn.edu/

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13.11.2024
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Latest posts by Alessandro Bartolomucci Lab @bartolomuccilab

An announcement of Sabrina Mederos's fellowship and a description of her research.

An announcement of Sabrina Mederos's fellowship and a description of her research.

πŸ”¦βœ¨ Research Network Spotlight!βœ¨πŸ”¦

Sabrina Mederos, PhD candidate at UC Davis, is one of two 2025-2026 Bruce McEwen Fellowship awardees through our Research Network. Check out a description of Sabrina's research below.

@bartolomuccilab.bsky.social @jennytung.bsky.social @smacklab.bsky.social

28.10.2025 20:58 πŸ‘ 2 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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When Alexander Easton @durhameaston.bsky.social and I stepped in as EIC of Neuroscience & Biobehavioral Reviews, we led the revision of the Aims and Scope of this highly successful journal.

Our Editorial outlines major updates/expansions to the Aims & Scope
www.sciencedirect.com/science/arti...

21.10.2025 13:51 πŸ‘ 5 πŸ” 4 πŸ’¬ 0 πŸ“Œ 0
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βœ¨πŸ”¦Research Network Spotlight!πŸ”¦βœ¨

@ctestard.bsky.social at Harvard University is the second recipient of a 2025-2026 Pilot & Feasibility award from our Research Network. Check out a description of Dr. Testard's project below.

@bartolomuccilab.bsky.social @jennytung.bsky.social @smacklab.bsky.social

14.10.2025 15:27 πŸ‘ 7 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0
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Proud to announce the publication of our new paper describing the design, chemical synthesis and testing of a novel class of Complement 3a Receptor (C3aR) agonists and antagonists derived from the TLQP-21 peptide

@pubs.acs.org Journal of Medicinal Chemistry

pubs.acs.org/doi/10.1021/...

04.09.2025 12:43 πŸ‘ 5 πŸ” 4 πŸ’¬ 0 πŸ“Œ 0
Animal Models for the Social Dimensions of Health and Aging Research Network

Remider!
Applications for the McEwen Career Development fellowship in Social Determinants of Health supported by the NIA-BSR High Priority Research Network animalsocialaging-network.org are now open!

apply here animalsocialaging-network.org/funding/fell...

03.07.2025 09:13 πŸ‘ 2 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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Fellowships | Animal Models for the Social Dimensions of Health and Aging Research Network

πŸ“’Applications for the McEwen fellowship are now open!

We expect to award 1-3 fellowships (up to $6,000 each) to early-career scientists with a proposal within the broad scope of our research network’s interests.

Deadline: July 15

Apply here: www.animalsocialaging-network.org/funding/fell...

15.06.2025 17:03 πŸ‘ 4 πŸ” 2 πŸ’¬ 1 πŸ“Œ 2

Reminder - funding opportunity available trough the @animalsocaging.bsky.social

Pilot & Feasibility Awards
Application period - June 1 to June 30

B. McEwen Career Development Fellowship
Application period - June 15 to July 15

Small/Working Group Awards
Application period - July 1 to July 31

12.06.2025 10:26 πŸ‘ 5 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0
Animal Models for the Social Dimensions of Health and Aging Research Network

πŸ“£ @animalsocaging.bsky.social NIA-funded high priority research network - funding available soon!πŸ“£

Stay tuned for 3 RFAs:
1. Pilot awards - June 30th
2. The Bruce McEwen Fellowship - July 15
3. Small/working group - July 31

More info on the network: www.animalsocialaging-network.org

19.05.2025 14:42 πŸ‘ 4 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0
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Epigenetic biomarkers of mortality risk in mice under chronic social… | Alessandro Bartolomucci New Study: β€œEpigenetic biomarkers of mortality risk in mice under chronic social stress,” just published in GeroScience. https://lnkd.in/dqPGrQx4 Our study used a large cohort of mice (350+) exposed...

New Study alert: β€œEpigenetic biomarkers of mortality risk in mice under chronic social stress" @geroscience.bsky.social

lnkd.in/dqPGrQx4

Mathematical models identified epigenetic biomarkers of mortality risk and an association with blood glucose levels, informing on individual aging trajectories.

09.06.2025 16:23 πŸ‘ 3 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
A graphic describing the details related to applying for the Pilot awards of the Animal Models Social Aging network. Visit animalsocialaging-network.org for details.

A graphic describing the details related to applying for the Pilot awards of the Animal Models Social Aging network. Visit animalsocialaging-network.org for details.

πŸ“’Applications are OPEN for our Pilot awards!

Individual or mentored projects available with up to $20,000 in total costs! Read the full RFA and apply at the link below!

www.animalsocialaging-network.org/funding/pilo...

@smacklab.bsky.social @bartolomuccilab.bsky.social @jennytung.bsky.social

01.06.2025 17:01 πŸ‘ 6 πŸ” 5 πŸ’¬ 0 πŸ“Œ 2
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Ecological Realism Accelerates Epigenetic Aging in Mice Living environment shapes mammalian aging, but laboratory conditions lack the ecological realism of natural social, physical, and microbial environments. Comparing traditionally laboratory-reared and...

New Research Network publication alert!

@sheehanmj.bsky.social and @matthewzipple.bsky.social, both recipients of Network Pilot & Feasibility awards, have published a paper in Aging Cell on ecological realism and epigenetic aging in mice. Congratulations, Mike and Matthew! doi.org/10.1111/acel...

23.05.2025 14:16 πŸ‘ 6 πŸ” 5 πŸ’¬ 0 πŸ“Œ 1
Animal Models for the Social Dimensions of Health and Aging Research Network

πŸ“£ @animalsocaging.bsky.social NIA-funded high priority research network - funding available soon!πŸ“£

Stay tuned for 3 RFAs:
1. Pilot awards - June 30th
2. The Bruce McEwen Fellowship - July 15
3. Small/working group - July 31

More info on the network: www.animalsocialaging-network.org

19.05.2025 14:42 πŸ‘ 4 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0
Animal Models for the Social Dimensions of Health and Aging Research Network

πŸ“£New network funding available soon!πŸ“£

The Request for Applications for our Research Network's pilot awards (June 1-June 30), the Bruce McEwen Fellowship (June 15-July 15), and small/working group awards (July 1-July 31) will be live on our website (www.animalsocialaging-network.org) in two weeks!

16.05.2025 16:23 πŸ‘ 5 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0

That`s a big one!
congrats to the outstanding team of co-authors

14.05.2025 09:28 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Our NIA funded High Priority Research network on Animal Models for the Social Dimension of Health and Aging just landed on Bsky @animalsocaging.bsky.social
- follow us for updates and new RFAs

www.animalsocialaging-network.org

@smacklab.bsky.social @jennytung.bsky.social

13.05.2025 08:02 πŸ‘ 2 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0

🎀Hey, is this thing on?

The Animal Models for the Social Dimensions of Health and Aging Research Network is on Bluesky! We are an NIA-funded network headquartered at UMN, ASU, UNC, and Duke that supports early-career scientists using animal models to study social aging. New funding available soon!

12.05.2025 17:03 πŸ‘ 5 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0

🚨 Great opportunity for an excellent post doc with a fantastic international group of top notch scholars.

08.05.2025 06:23 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Read here our original article showing the biological age prediction by accumulating stochastic variation alone. With @meyer.bsky.social and a wonderful cover art designed by @maayanvisuals.bsky.social www.nature.com/articles/s43...

30.04.2025 06:45 πŸ‘ 8 πŸ” 4 πŸ’¬ 0 πŸ“Œ 1

Post on the study by the first author @claudiagil93.bsky.social

bsky.app/profile/clau...

25.04.2025 11:03 πŸ‘ 4 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Scarce and unpredictable, yet obesogenic: modeling the impact of food insecurity on adiposity in mice Click on the article title to read more.

Food insecurity drives obesity and adiposity, but how is unclear.
A recent study by @clemmensenc.bsky.social developed a mouse model for this phenomenon lnkd.in/d8pEp2qv
Happy to share a commentary written with @johnspeakman4.bsky.social with our take on that study
doi.org/10.1002/oby....

25.04.2025 10:56 πŸ‘ 7 πŸ” 5 πŸ’¬ 1 πŸ“Œ 1
A woman riding a bicycle in Stockholm, Sweden, on September 14, 2018.

A woman riding a bicycle in Stockholm, Sweden, on September 14, 2018.

The gap in life expectancy between the richest and poorest Swedes widened between 1960–2021. The cause of this trend was not increased inequality or a decline in social spending but an embrace of healthy lifestyles by the affluent. In PNAS: www.pnas.org/doi/10.1073/...

07.04.2025 21:15 πŸ‘ 14 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0

bad news for freshwater quality in minnesota and midwest, very bad in the Twin Cities.

08.04.2025 07:35 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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🧠πŸ’₯ For #Dopamine (DA) & #Memory lovers!

πŸ“’ New paper!! we show that memory capacity (MC) in mice can be expanded from 6 to 8 objects using low doses of a D1 receptor agonist. Higher doses? Paradoxically, they reduce MC.

#Tigem
#Consiglio Nazionale delle Ricerche

lnkd.in/d9skfGeb

03.04.2025 09:35 πŸ‘ 4 πŸ” 2 πŸ’¬ 1 πŸ“Œ 0
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We recently published
@geroscience.bsky.social
the development and validation of the mouse social frailty index (mSFI) link.springer.com/article/10.1...

We now report a detailed step-by-step resource paper describing how to conduct the mSFI.
bio-protocol.org/en/bpdetail?...

02.04.2025 06:37 πŸ‘ 11 πŸ” 4 πŸ’¬ 0 πŸ“Œ 0
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Food insecurity promotes adiposity in mice Objective The obesity epidemic, driven by a complex interplay of environmental and biological factors, remains a significant global health challenge. Herein, we investigate the impact of food insecu...

🌟 Exciting News! 🌟
I am thrilled to share that my first paper as the first author, Food insecurity promotes adiposity in mice, is now published in #ObesityJournal #ObesitySociety

doi.org/10.1002/oby....

#Foodinsecurity #Obesity #PhD

1/9πŸ§΅πŸ‘‡

27.03.2025 19:12 πŸ‘ 20 πŸ” 7 πŸ’¬ 2 πŸ“Œ 2

Proud to share the work of my forst ever PhD student and first author of this paper @dylanduerre.bsky.social!! Here, he summarizes it perfectly! #brownfat #metabolism #BCAA #heme @uwmadison.bsky.social @uofutahcihd.bsky.social

25.03.2025 14:41 πŸ‘ 19 πŸ” 11 πŸ’¬ 0 πŸ“Œ 1
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Aging activates escape of the silent X chromosome in the female mouse hippocampus Aging activates the silent X chromosome, increasing escape expression, and potentially cognitive resilience, in the female mouse.

"We could all use a little more X!" Thrilled our new study is out. Aging "wakes up" the silent X chromosome in the female brain - and this contributes cognitive resilience. Spearheaded by @margaretgadek.bsky.social in Science Advances. www.science.org/doi/10.1126/...

06.03.2025 05:24 πŸ‘ 49 πŸ” 21 πŸ’¬ 2 πŸ“Œ 0
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Exclusive: NIH to terminate hundreds of active research grants Studies that touch on LGBT+ health, gender identity and DEI in the biomedical workforce could be terminated, according to documents obtained by Nature.

In an unprecedented move, the US National Institutes of Health (NIH) has begun mass terminations of research grants that fund active scientific projects because they no longer meet β€œagency priorities”….

πŸ§ͺ #AcademicSky

www.nature.com/articles/d41...

06.03.2025 06:52 πŸ‘ 165 πŸ” 139 πŸ’¬ 14 πŸ“Œ 12
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Why women’s brains are more resilient: it could be their β€˜silent’ X chromosome Study in mice and human cadavers hints that a brain-protective gene in the chromosome becomes more active with age.

Women tend to live longer than men and are often more resilient to cognitive decline as they age.

Now researchers might have uncovered a source for this resilience: the second X chromosome in female cells that was previously considered β€˜silent’

https://go.nature.com/3F40x10

06.03.2025 10:07 πŸ‘ 123 πŸ” 32 πŸ’¬ 3 πŸ“Œ 6
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Outdoor heat in older adults and accelerated biological (epigenetic) aging
www.science.org/doi/10.1126/...

27.02.2025 00:07 πŸ‘ 106 πŸ” 26 πŸ’¬ 1 πŸ“Œ 4