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François Leulier

@francoisleulier

Scientist, Biologist @CNRS Director and Group leader @IGFLyon @ENSLyon We study how the #Microbiome together with #Nutrition influence #Juvenile #Physiology using #InMice and #Drosophila as models.

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Latest posts by François Leulier @francoisleulier

« Advanced Biology » : the integration of all this…

06.03.2026 11:08 👍 0 🔁 0 💬 0 📌 0

First it was Natural History, then Biochemistry, then Molecular Biology, then Systems Biology, then Synthetic Biology, then Generative Biology … what will come next 🤔?

06.03.2026 07:24 👍 4 🔁 1 💬 2 📌 0
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🎉En 2025, le Cercle FSER a organisé des rencontres avec plus de 20 000 élèves !
👏Merci à notre équipe engagée et à des projets comme Declics, Comptoir des sciences et d'autres qui nous permettent de faire grandir le lien entre sciences, éducation et société.

05.03.2026 15:04 👍 2 🔁 1 💬 0 📌 0

« Je suis persuadée qu’on fait de la meilleure science lorsqu’on ne vient pas tous du même moule »

Rencontre avec Julie Delon, professeure et directrice adjointe du département de mathématiques et applications de l’ENS-PSL.

👉 Lire l’entretien complet : https://psl.pulse.ly/44fxusrue6

05.03.2026 10:59 👍 1 🔁 1 💬 0 📌 0
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Nicolas Rivron, Group Leader at IMBA, received an Honorable Mention for the 2026 ISSCR Early Career Impact Award. The award recognizes his joint work with Naomi Moris on stem cell–based embryo models and their ethical governance: https://imba.science/4rQrqcq

04.03.2026 08:25 👍 9 🔁 3 💬 0 📌 0
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Preprint Editors – Development's next step into the preprint landscape Summary: This Editorial announces a call for Preprint Editors in Development to help expand the journal's relationship with preprints by curating our ‘In preprints’ articles.

New from @dev-journal.bsky.social: we're launching a new initiative and hiring Preprint Editors to help navigate the growing world of preprints in developmental & stem cell biology

Join our community & shape the future of research

journals.biologists.com/dev/article/...

02.03.2026 14:54 👍 55 🔁 39 💬 1 📌 0
Insect immunity: the guardian of homeostasis and symbiosis Roscoff (Bretagne), France, June 22-26, 2026Deadline for application: March 4, 2026

📢 Insect immunity researchers: don’t miss this! The Jacques Monod International Conference – “Insect immunity: the guardian of homeostasis and symbiosis” will take place June 22–26, 2026 at the Station Biologique de Roscoff 🇫🇷

Submit & register:
www.insb.cnrs.fr/fr/insect-im...

02.03.2026 16:38 👍 6 🔁 3 💬 1 📌 0
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A great pleasure to have @haddad-tovolli.bsky.social today from @idibaps.bsky.social as an external speaker! A great shoutout for female brain research from an amazing person, friend and young scientist 🤯 @igflyon.bsky.social

02.03.2026 10:12 👍 5 🔁 1 💬 0 📌 0

Final version @nature.com of our paper describing unconventional multicellular development in a choanoflagellate inhabiting an extreme environment. A ton of new data since the first @biorxivpreprint.bsky.social preprint (which we've kept updating).

A brief 🧵 (carried over from the old place)

28.02.2026 08:12 👍 361 🔁 146 💬 16 📌 16
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Le circuit de la récompense passe aussi par l'intestin Une nouvelle étude montre que couper la communication intestin-cerveau chez la souris réduit la libération de dopamine et la motivation face à la nourriture comme aux drogues. Le plaisir ne serait pas...

Une nouvelle étude montre que couper la communication intestin-cerveau chez la souris réduit la libération de dopamine et la motivation face à la nourriture comme aux drogues. Du plaisir aux additions, tout ne se joue donc pas dans le cerveau.

27.02.2026 07:18 👍 24 🔁 8 💬 2 📌 1
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The gut-brain vagal axis governs mesolimbic dopamine dynamics and reward events Gut-brain vagal signals gate dopamine ensembles, reshaping reward and motivation beyond a brain-centric view.

Avec les précieuses explications d'Oriane Onimus, docteure en neurosciences de l’Université Paris Cité et première autrice de cette étude parue dans Science Advances.

27.02.2026 07:18 👍 15 🔁 4 💬 0 📌 0
This image depicts a nematode with fluorescently labeled bacteria in its intestine (left), illustrating microbial metabolic input. On the right, fluorescently marked epidermal lysosomes (top), intestinal lysosomes (middle), and lipid droplets (bottom) highlight the organelles engaged in lysosome-dependent lipid degradation. Together, the image visualizes a microbiota–lysosome axis through which bacterial tryptophan metabolism reprograms host lipid homeostasis. Image Credit: Kenan Zhang

This image depicts a nematode with fluorescently labeled bacteria in its intestine (left), illustrating microbial metabolic input. On the right, fluorescently marked epidermal lysosomes (top), intestinal lysosomes (middle), and lipid droplets (bottom) highlight the organelles engaged in lysosome-dependent lipid degradation. Together, the image visualizes a microbiota–lysosome axis through which bacterial tryptophan metabolism reprograms host lipid homeostasis. Image Credit: Kenan Zhang

Microbial metabolites can influence host physiology. This study shows that #microbial production of #indole from #bacterial #tryptophan catabolism enhances #lysosomal acidification & lipase activity in nematodes & mammalian hepatocytes @plosbiology.org 🧪 plos.io/3ZZAsaI

27.02.2026 08:55 👍 11 🔁 6 💬 1 📌 0
ShineGAL4 FLP-out clones

ShineGAL4 FLP-out clones

#Drosophila calling. Delighted to share our new collection of ShineGAL4 drivers for CNS, FB, muscles, enterocytes, oenocytes and MTs made by @vgirard.bsky.social, @sebsorge.bsky.social and colleagues @crick.ac.uk. All at Bloomington @bdsc.bsky.social

@dev-journal.bsky.social
tinyurl.com/4jpw9jd6

25.02.2026 16:03 👍 43 🔁 23 💬 1 📌 2
New registration New registration

The registration is open! Junior #Drosophila PIs, join us for inspiring scientific discussion, contribute a talk and listen to our keynote speaker, Eugenia Chiappe. We meet in Palmela, Portugal from June 1st to 3rd. Register soon as spots are limited!

congressos.mundiconvenius.pt/geral/inseri...

20.02.2026 15:04 👍 18 🔁 14 💬 0 📌 3
Annonce officielle de l’IGFL pour le recrutement du poste cité ci-dessus

Annonce officielle de l’IGFL pour le recrutement du poste cité ci-dessus

L’IGFL recrute un•e Professeur•e des Universités en biologie moléculaire (CNU 64), UCBL Lyon 1.
Enseignement L2-M2 (Biochimie et Biologie Moléculaire) + projet en biologie moléculaire des eucaryotes au sein de l’IGFL.
Détails: shorturl.at/K5Dno
#Recrutement #BiologieMoleculaire

17.02.2026 10:00 👍 6 🔁 8 💬 0 📌 1
Time-calibrated phylogeny of the family Drosophilidae showing major species groups, surrounded by representative adult flies that highlight the remarkable morphological diversity of this model insect group. The composite image was created using Microsoft PowerPoint. Fly photographs were taken by Darren J. Obbard and are published under the Creative Commons Attribution License with permission.

Time-calibrated phylogeny of the family Drosophilidae showing major species groups, surrounded by representative adult flies that highlight the remarkable morphological diversity of this model insect group. The composite image was created using Microsoft PowerPoint. Fly photographs were taken by Darren J. Obbard and are published under the Creative Commons Attribution License with permission.

The #fly community aims to achieve a comprehensive genomic study of the Drosophilidae family. @pankajd.bsky.social @bernardkim.bsky.social @petrovadmitri.bsky.social @darrenobbard.bsky.social present a comparative gene annotation for 301 #Drosophilidae species @plosbiology.org 🧪 plos.io/4c3pyrI

19.02.2026 13:55 👍 55 🔁 29 💬 0 📌 0
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The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of gut health - Nature Reviews Gastroenterology & Hepatology This Consensus Statement provides a definition of the term ‘gut health’, as well as a discussion of the relevant domains that contribute to gut health and a framework for appropriate use of the term i...

Excited to share our latest publication! 🎉
This consensus statement, led by @isappscience.bsky.social, establishes an evidence-based definition of gut health relevant to clinical practice & dietary & biotic interventions.
www.nature.com/articles/s41...
#GutHealth #Microbiome #ISAPP #DigestiveHealth

18.02.2026 20:08 👍 8 🔁 7 💬 0 📌 1
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EMBO Press co-evolves with molecular ecology and evolutionary biology - The EMBO Journal The EMBO Journal - Molecular ecology and evolution are central to understanding how biological systems function, interact, and diversify. A special issue of this journal reflects the growing...

Read how @embopress.org is expanding its focus on molecular ecology and evolution as central underpinnings of functions/interactions/diversification of biological systems – by @yehumoran.bsky.social, @berndpulverer.bsky.social, and our new team of Editorial Advisors
link.springer.com/article/10.1...

18.02.2026 19:47 👍 21 🔁 12 💬 0 📌 1
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Seeon - Deutsche Gesellschaft für Hygiene und Mikrobiologie Microbiota, Probiotics and Host    Seeon- Save the date 2026 Registration Abstract Template 2026   We are looking forward to meeting you there! Don’t forget your swimwear, sunscreen and running gear ...

Registration for the 18th Annual Seeon Conference on Microbiota, Probiotics and Host is now open! 🎉

We’re looking forward to welcoming you in Seeon!

When: June 24-26
Where: Seeon Monastery, Germany (near Munich)
Program: www.dghm.org/seeon/
Registration: app1.edoobox.com/SPP1656/Seeo...

18.02.2026 08:48 👍 6 🔁 5 💬 0 📌 2
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Des bactéries mangeuses de PFAS

Nombre d’objets du quotidien recèlent des PFAS, des molécules synthétiques quasi indestructibles. Mais ces milliers de composés s’accumulent dans la nature et nos organismes. L’une des pistes pour s’en débarrasser : la bioremédiation, qui élimine les polluants à l’aide d’organismes vivants.

17.02.2026 08:09 👍 20 🔁 9 💬 0 📌 1
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Tissue mechanics and systemic signaling safeguard epithelial tissue against spindle misorientation Bosveld et al. identified a multilayered system of safeguards that reuses homeostatic mechanisms to maintain epithelial integrity and cell number in the face of spindle misorientation. This work delin...

How resilient are tissues to cell mispositioning and loss, and how do they restore their cell numbers?

Check our latest work, from @ybellaichelab.bsky.social
Congratulations to all authors.

Artwork from the artist @lale-alpar.bsky.social
(lalealpar.com)

www.cell.com/developmenta...

17.02.2026 06:31 👍 30 🔁 16 💬 4 📌 1

igfl.ens-lyon.fr/offres/offre...

17.02.2026 09:45 👍 0 🔁 0 💬 0 📌 0
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Accueil IGFL — Institut de Génomique Fonctionnelle de Lyon Personal tools

Le projet de recherche s’inscrira dans l’une des équipes de @igflyon.bsky.social

igfl.ens-lyon.fr

17.02.2026 08:06 👍 0 🔁 0 💬 1 📌 0

Un poste de Professeur des Universités va être ouvert lors de la campagne d’emploi 2026 à l’université Claude Bernard Lyon1 -
Profil Recherche : Biologie Moléculaire des Eucaryotes.
Profil Enseignement: Biologie Moléculaire.
Profil ci-joint.
Merci de diffuser dans vos réseaux.

17.02.2026 08:04 👍 14 🔁 20 💬 1 📌 0
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Emmanuel Macron veut transformer l’organisation de la recherche Le chef de l’Etat installe un Conseil présidentiel chargé de l’éclairer sur la marche de la science, et donne dix-huit mois aux organismes et aux universités pour « remettre de la clarté » dans le pil...

Les 18 mois sont largement écoulés et… rien. #ESR

www.lemonde.fr/politique/ar...

15.02.2026 07:13 👍 3 🔁 4 💬 1 📌 0
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The balance of fiber and protein intake has been largely overlooked

This timely review in @natrevgastrohep.nature.com updates factors that influence human digestion and absorption of protein in the small intestine and protein fermentation in the colon:

https://tinyurl.com/4ebkb6js

13.02.2026 12:01 👍 9 🔁 5 💬 0 📌 0

We were all very sad to learn the death of Pierre Capy. Pierre was a professor at University Paris Saclay, in the 1990s, he started a group working on the evolutionary genomics of transposable elements; this group is still very active today. He was a great teacher, mentor, and colleague.

13.02.2026 13:55 👍 7 🔁 8 💬 2 📌 0
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My contribution to the Lararium.

12.02.2026 07:37 👍 1 🔁 1 💬 0 📌 0
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Paris Brain Institute Call for Junior Group Leaders in Artificial Intelligence and Data Science | Paris Brain Institute The Paris Brain Institute is launching a Call for Junior Group Leaders, inviting outstanding early-career scientists in artificial intelligence, data science, computational neuroscience, and related f...

🧠 The Paris Brain Institute is launching a Call for Junior Group Leaders, inviting early-career scientists to establish their own independent research groups within one of Europe’s most dynamic neuroscience research centers.

👉 More information: parisbraininstitute.org/news/paris-b...

#Hiring #AI

11.02.2026 17:06 👍 17 🔁 11 💬 1 📌 0

Very last chance to join us (Deadline tomorrow Feb 10!) at this Developmental Biology meeting!
Have a nice story? Come and discuss it with editors from @embojournal.org @plosbiology.org and @dev-journal.bsky.social !
A one hour info session from @erc.europa.eu will also be presented!

09.02.2026 16:00 👍 8 🔁 13 💬 0 📌 2