HItoshi Sawa

Our paper was published in Genetics!
academic.oup.com/genetics/adv...

🟡🚄+🗻

Differential functions of multiple Wnts and receptors in cell polarity regulation in C. elegans Metazoan species possess multiple Wnt ligands and receptor genes that regulate diverse developmental processes. Because these genes often act redundantly, analysis of single-gene mutants does not nece...

In worms, polarity of somatic cells are controlled by 3 Wnt and 3 receptors. We comprehensively combined their mutations to uncover their specific functions.We also showed that Wnts have both instructive and permissive functions to control cell polarity orientation.
www.biorxiv.org/content/10.1...

It' getting cold.

🙃🗻

First snow cap🗻

New paper from the lab! Many animal cells exhibit chiral cell surface dynamics, which are proposed to drive left–right asymmetric patterning. However, the molecular mechanisms linking these events remain unclear. authors.elsevier.com/a/1l%7E7B3QW...

Very sad news, John Gurdon has died.

A developmental biologist's developmental biologist, Nobel prize winner

His work is the foundation of much of today's dev & stem cell bio.

An inspiration to many, including me. Always asking questions & wanting the answers

www.magd.cam.ac.uk/news/profess...

Colorful Mt. Fuji🗻

The paper was introduced in JC. I was so impressed that the gradient is established in this system with huge? extracellular space (volume of media) compared to limited space in vivo. I guess the gradient is formed by spreading along the membrane rather than diffusion into media. 🎉 for great work!

Crossing on red light!
#Nara

Poster prize too🎉‼️😊

Congratulation for the grand prize! #worm25 Art Show

As it’s my first time joining Worm Meeting, I was excited to participate in Worm Art show as well.
This year’s topic is resilience. In times of scarcity, worms gather holding one another to reach new grounds. Alone - they are fragile, together - they rise. Even the sky yields in unity. #worm25

My wormy watch😍

Totoro?

You have to hold your breath while we cross the bridge.

#SpiritedAway

Snowcap refreshed!

Since the mountain is isolated, we can go around it to see it in various angles.

Colorful Mt Fuji

咲耶姫

御帝𠮷野

兼六園熊谷

半兵衛白紅桜

Our Institute preserve >200 cherry species. We have open house today.

Shidare-Zakura + MIshima Sakura ＠Sano museum

Big news: we are setting up a new non-profit organization to run bioRxiv and medRxiv. It's called openRxiv [no it's not a new preprint server; it's dedicated organization to oversee the servers] openrxiv.org 1/n

March 3rd is Hina-Matsuri (Doll's Festival?) day.

Kawazu cherry 🌸

Making intrabodies from antibodies just got easier! Learn how we made 𝟭𝟵 intrabodies to bind and light up peptides and histone modifications in live cells. And thanks to Academia, all sequences are freely available. (video credit: Yuko Sato @YukoSatoT2) (1/15)
www.biorxiv.org/content/10.1...

Here’s a story about actual Nazis, the Original Gastruloid, and the lengths scientists will go for other scientists and for science itself. Welcome to Episode Two of the #LongBibliography
#DevBiol #SciHist 🧵. 1/13

This has been a big controversial issue in Japan🥺

Parasitoid wasp venoms degrade Drosophila imaginal discs for successful parasitism Two parasitoid wasp venom proteins induce imaginal disc degradation of its host fly Drosophila larva, ensuring parasitism success.

I am thrilled that our paper, which is packed with our 10 years of data on the venom proteins of the parasitoid wasp Asobara japonica, has just been published!

Parasitoid wasp venoms degrade Drosophila imaginal discs for successful parasitism | Science Advances www.science.org/doi/10.1126/...

First 🌅 of the year