Elena Garcia-Perez

Bringing the genetically minimal cell to life on a computer in 4D Simulating the complete cell cycle of the minimal cell provides a platform to understand the progression of complete states over time. The spatial heterogeneity of the intracellular environment can strongly affect biochemical reactions that control phenotypes.

Now online! Bringing the genetically minimal cell to life on a computer in 4D

Assembly, architecture and functional roles of microbial surface layers - Nature Reviews Microbiology Surface layers (S-layers) are ubiquitous protein assemblies that coat prokaryotic cells, with their functional roles increasingly coming into focus. In this Review, Isbilir and colleagues discuss rece...

Assembly, architecture and functional roles of microbial surface layers
#microbiology #archaea #bacteria
@natrevmicro.nature.com
www.nature.com/articles/s41...

Localized glutamine leakage drives the spatial structure of root microbial colonization Plant roots release exudates to encourage microbiome assembly, which influences the function and stress resilience of plants. How specific exudates drive spatial colonization patterns remains largely ...

Read the paper 👉 Localized glutamine leakage drives the spatial structure of root microbial colonization | Science www.science.org/doi/10.1126/...

Engineered geminivirus replicons enable rapid in planta directed evolution Directed evolution can rapidly generate genetic variants with new and enhanced properties, yet efficient platforms for performing such evolution directly in plant cells have been lacking. We developed...

Engineered geminivirus replicons enable rapid in planta directed evolution

www.science.org/doi/10.1126/...

Engineering Conditional Transgene Expression in Nicotiana benthamiana Nicotiana benthamiana has emerged as a premier plant biofactory for recombinant protein and metabolite production due to its high metabolic versatility, ease of cultivation and permissiveness to tran...

Delighted to have written this review alongside my former PhD supervisors, Diego Orzaez and Marta Vazquez-Vilar, where we discuss how synthetic gene circuits can unlock the full potential of N. benthamiana as a programmable plant biofactory 🌱🎮
🔗 onlinelibrary.wiley.com/doi/10.1111/...

Chromoprotein-modified plant pathogenic bacteria: tools for experimental tracking and visualization Microbiology research often requires tracking of specific bacterial strains within a host infection system or in the environment, as well as differentiation of strains in a co-infection or microbe-mic...

If anyone wants some plant pathogens in fun colors let me know 🌈🧫 #Xylella #Pseudomonas #Pantoea
Shoutout to @atinygreencell.bsky.social for inspiration and high quality source material
www.biorxiv.org/content/10.1...

Lab to field: Challenges and opportunities for plant biology Plant-microbe research offers many choices of model and strain and whether a field-first or lab-first approach is best. However, differences between l…

1/2 What's best: a field-first or lab-first approach? No easy answers but differences between lab and field should not be seen as failure but motivate further inquiry and allow complementary discovery. Read our thoughts on this here:
www.sciencedirect.com/science/arti...

Earlham Biofoundry The Earlham Biofoundry is a resource for the UK biology and biotechnology communities, providing a platform to undertake large-scale projects.

Led by experts in #synbio, large-scale design and #automation programming, the Earlham Biofoundry provides high-throughput #engineering of biological systems, open to the bioscience community.

Discover more here:

Happy to share the new article from my former lab at IBMCP — the final chapter of my PhD!
We optimized geminivirus-based vectors for the controlled expression of recombinant proteins in plants, using autobioluminescence as a real-time reporter 💡🧬🌱

If you’re curious… 👀:
pubs.acs.org/doi/full/10....

Inspiring time at @ismpmi.bsky.social, where I had the honour of sharing my PhD work on repurposing viruses for plant biomanufacturing. It was great to reconnect with old friends (special shoutout to @geminiteamlab.bsky.social 💚) and meet so many researchers pushing plant–microbe science forward 🌱🧬🧫