Renil Mathew

Excited to give the Feindel Lecture at The Neuro on Monday 26th Jan in Montreal. Streamed and recorded too. Come hear about our new SASS MRI technique just out in print in @natmethods.nature.com
@westernuwin.bsky.social @theneuro.bsky.social

Our article on using non-steady-state scans for event related fMRI is now out in print (remember print?). www.nature.com/articles/s41...

And as a bonus, the journal (Nature Methods), did a News & Views piece www.nature.com/articles/s41...

Lead author @renilmathew.bsky.social

Taking advantage of non-steady-state imaging to increase temporal SNR for fMRI - Nature Methods A technique called SASS increases temporal signal-to-noise ratio for functional MRI by taking advantage of the time it takes to reach steady state when collecting functional images.

News and views article on SASS-fMRI from Nature methods.
www.nature.com/articles/s41...

Great honour to receive Dr Tutis Villis Graduate Award in Neuroscience. 🙏

Thank you @northernthrux.bsky.social — truly honoured. If it brought a tear to your eye, I’ll take that as the highest compliment!

Just published my "Programming for Psychologists" course! 👩‍💻 github.com/Naubody/prog...

Designed for Psychology & Cognitive Neuroscience Master's students starting their programming journey at @vuamsterdam.bsky.social.

Feel free to share! Feedback welcome!

Stimulus-modulated approach to steady state (SASS): a flexible paradigm for event-related fMRI - Nature Methods Stimulus-modulated approach to steady state (SASS) is an acquisition scheme for event-related fMRI that generates data with high temporal signal-to-noise ratios interspaced with acquisition-free perio...

Stimulus-modulated approach to steady state (SASS): an acquisition scheme for event-related fMRI that generates data interspaced with acquisition-free periods for stimulus presentation or response reporting.
@renilmathew.bsky.social @northernthrux.bsky.social

www.nature.com/articles/s41...

Signal in the silence: Western researchers uncover hidden potential in discarded MRI data - Western News Western University researchers have uncovered hidden potential in the historically discarded MRI data that is recorded in start-up period of scans.

#WesternU researchers have unlocked the hidden potential in discarded MRI data, developing a new technique transforming how scientists study the brain. @schulichmeddent.bsky.social

Signal in the silence: Researchers uncover hidden potential in discarded MRI data - Schulich School of Medicine & Dentistry - Western University A new technique is transforming how scientists use fMRI to study the brain.

Researchers at @westernu.ca have unlocked surprising power in the first seconds of a functional MRI scan. Short, deliberate pauses boost the signal that follows – producing sharper, more responsive images of brain activity.

Published today in @natmethods.nature.com.

If the community wants, we have XA60 and VE12U versions we can make available as a C2P for Siemens scanners. And we have a Paravision 360 v3.6 available for Bruker. The processing code is equally simple and is posted with the paper.

Timing tweak turns trashed fMRI scans into treasure Leveraging start-up “dummy scans,” which are typically discarded in imaging analyses, can shorten an experiment’s length and make data collection more efficient, a new study reveals.

This article in The Transmitter covering our paper may be one of the best scientific content headlines of all time. www.thetransmitter.org/fmri/timing-...

Thanks a lot!!

Super excited about my first first-author paper, now out in @natmethods.nature.com 🥳

Stimulus-modulated approach to steady state (SASS): a flexible paradigm for event-related fMRI - Nature Methods Stimulus-modulated approach to steady state (SASS) is an acquisition scheme for event-related fMRI that generates data with high temporal signal-to-noise ratios interspaced with acquisition-free perio...

Excited to share my first first-author paper in Nature Methods!🤩

A quest to solve fMRI–EEG interference revealed a hidden strength in the usually discarded “dummy” scans. That spark became SASS-fMRI — boosting sensitivity and enabling silent, flexible experiments.
www.nature.com/articles/s41...

On this day in 1920, Dr. Frederick Banting woke at 2 a.m. in #LdnOnt and jotted down a 25-word idea — setting in motion the discovery of insulin.

105 years later, Banting's legacy continues. A heritage plaque at #WesternU now marks the historic moment.

Learn more: www.uwo.ca/projects/her...

Thrilled to share that the central work of my PhD will be published soon.😬

A non-invasive approach to awake mouse fMRI compatible with multi-modal techniques Abstract. Mouse functional magnetic resonance imaging (fMRI) studies contribute significantly to basic fundamental and translational neuroscience research. Performing fMRI in awake mice could facilita...

A new open source nonsurgical head restraint for awake mouse fMRI from our lab led by Sam Laxer. TL;DR Scanning about 25% longer than with a surgically implanted head post, combined with some training gives good results. Happy mice = happy rsfmri networks. direct.mit.edu/imag/article...

fMRI can do more than you think Advances in brain imaging technology provide new and different information about the brain.

ICYMI: Recent technological advances in functional MRI provide a range of new information about brain physiology. Collaboration between engineers and neuroscientists will help maximize these gains, writes Laura Lewis.

www.thetransmitter.org/human-neurot...

We're excited share our perspective on whether you only use 10 bits/s of your brain.

Imaging cortical layers to understand brain as network organ This spatial scale, bridging cells and brain areas, has been overlooked in human brain research. But advances in fMRI technology are changing that.

Human neuroscience research has largely overlooked the mesoscale, which bridges cells and brain areas. But new advances in fMRI technology are changing that, writes Laurentius Huber @layerfmri.bsky.social.

#neuroskyence

www.thetransmitter.org/future-of-fm...

New revised preprint on the SASS paradigm now with extensive human experiments, showing its broader applicability—check it out!

The SASS (Stimulus-modulated Approach to Steady State) fMRI paradigm leverages noise-free AFP (Acquisition Free Period) segments to present stimuli and capture high tSNR BOLD responses during the subsequent AB (Acquisition Block). (2/n)

Western University is seeking applications for Canada Excellence Research Chairs. Please reach out if you are interested in Theme 2: Neuroscience. Western has extraordinary strengths in cognitive, molecular and systems neuroscience across species (rodents, NHPs, humans) uwo.ca/research/cer...

Western Postdoctoral Fellowship Program Western University, in vibrant London, Ontario, delivers an academic and student experience second to none.

If you would like to postdoc in ultra high field MRI (3T+7T human, 9.4T+15.2T marmoset and mouse) in a well funded lab with tons of great neuroscience collaborations, drop me a DM soon.

Stimulus-modulated approach to steady-state: A new paradigm for event-related fMRI Functional MRI (fMRI) studies discard the initial volumes acquired during the approach of the magnetization to its steady-state value. Here, we leverage the substantially higher temporal signal-to-noi...

Since I have a new set of followers here, I thought I'd repost a link to our preprint that describes a new event related fMRI method that allows 2x the SNR of normal fMRI and beautiful single unit and EEG recordings, dead silence to present auditory stimuli etc. 1/2
www.biorxiv.org/content/10.1...