Alisa 愛理沙's Avatar

Alisa 愛理沙

@alisaiakupova

PhD student studying structural variants in allergy @mdc-berlin.bsky.social πŸ₯œ @preprintclub.bsky.social & long reads enthusiast. Moscow State & Univ of Groningen alumna

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19.11.2024
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Latest posts by Alisa 愛理沙 @alisaiakupova

I’m an organizer 🌚

24.02.2026 17:24 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

TCR signal strength determines Treg instability and discrimination of self versus non-self antigens https://www.biorxiv.org/content/10.64898/2026.02.12.705537v1

14.02.2026 10:19 πŸ‘ 3 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
Group photo
Text: Immunology & Inflammation Symposium
Berlin
Mar 17, 2026

Group photo Text: Immunology & Inflammation Symposium Berlin Mar 17, 2026

Registration now open for the I&I Berlin Symposium 2026!
Are you part of Berlin’s immunology community or planning to become one?

On March 17, 2026, the symposium bringing together researchers, clinicians, & early-career scientists working on immunology and inflammation.

06.02.2026 11:35 πŸ‘ 9 πŸ” 5 πŸ’¬ 0 πŸ“Œ 0

I don’t what that it is, maybe a (post)soviet education, but we think in the same direction 🀣

06.02.2026 09:24 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

You probably know that Berlin has many outstanding research groups working in #immunology. We’re bringing this community together for a one-day symposium on March 17th. Please register if you’re curious about Berlin science! 🧬🧯πŸ”₯ #immunosky #medsky

www.mdc-berlin.de/news/events/...

04.02.2026 15:48 πŸ‘ 5 πŸ” 4 πŸ’¬ 0 πŸ“Œ 0
Germinal centre IL-4 enforces tissue confinement of IgE memory - Nature Reviews Immunology A preprint by Villazala-Merino et al. shows that allergen-specific memory B cells must re-enter germinal centres to differentiate into IgE-producing plasma cells, which occurs in lymph nodes but not a...

by Leon Baronijan & Alberto Martin

30.01.2026 12:32 πŸ‘ 2 πŸ” 1 πŸ’¬ 0 πŸ“Œ 1

*maybe*

23.01.2026 02:55 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Il33 expressing cDC2s promote expansion of ILC2s and eosinophilia in fungal airway inflammation in male mice https://www.biorxiv.org/content/10.64898/2025.12.02.691763v1

04.12.2025 17:16 πŸ‘ 0 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

Targeted long-read sequencing enables comprehensive analysis of the genetic and epigenetic landscape of inherited myopathies https://www.medrxiv.org/content/10.64898/2025.12.06.25340828v1

08.12.2025 17:25 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Preprints of pandemic potential - new historical piece from me on the history of bioRxiv/medRxiv, their role in the pandemic, and the way forward. 1/n journals.asm.org/doi/10.1128/...

12.01.2026 14:33 πŸ‘ 75 πŸ” 39 πŸ’¬ 3 πŸ“Œ 5
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Insights into DNA repeat expansions among 900,000 biobank participants - Nature Human genetic variation influences instability of DNA repeats that commonly expand as we age.

Nature research paper: Insights into DNA repeat expansions among 900,000 biobank participants

go.nature.com/49mB0f6

08.01.2026 10:33 πŸ‘ 20 πŸ” 5 πŸ’¬ 0 πŸ“Œ 0
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🌚

07.01.2026 12:13 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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A vaccine targeting human IgE induces long-term protection against anaphylaxis in humanized mice A conjugate vaccine targeting human IgE induces long-term production of neutralizing antibodies and protects against anaphylaxis in humanized mice.

An experimental vaccine against IgE protects against #anaphylaxis in humanized mice!

Read the @science.org paper from a team at @pasteur.fr: https://bit.ly/4s35z1L
Listen to the discussion on our latest episode: https://bit.ly/44Ay1OG

19.12.2025 01:06 πŸ‘ 3 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

Multi-omics analysis reveals vitamin D metabolism, hyper-IgE genes, and epithelial barrier dysfunction in hazelnut allergy https://www.biorxiv.org/content/10.64898/2025.12.11.692994v1

14.12.2025 05:02 πŸ‘ 2 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Heterogeneity of the intestinal mononuclear phagocyte compartment in health and inflammatory bowel disease Single-cell transcriptomics resolves mononuclear phagocyte diversity in the human intestine in health and inflammatory bowel disease.

Single-cell transcriptomics resolves mononuclear phagocyte diversity in the human intestine in health and inflammatory bowel disease @sciimmunology.bsky.social
www.science.org/doi/10.1126/...

12.12.2025 20:24 πŸ‘ 6 πŸ” 4 πŸ’¬ 0 πŸ“Œ 0
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Escherichia coli-induced gut IL-33 release inhibits lung type 2 allergic responses Background The incidence of lung allergies is reduced in countries with higher prevalence of infection and environmental exposure to microbes. However, enteric bacterial infections do not always corre...

Tomorrow, Rob Crozier from the University of Toronto will present a #preprint from the Morais da Fonseca lab about how Escherichia coli-induced gut IL-33 release inhibits lung type 2 allergic responses.

www.biorxiv.org/content/10.1...

02.12.2025 17:51 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

distracts me from being sad that applying for a canadian working visa will likely take forever for me as a russian… *sigh*

01.12.2025 16:13 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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happy advent! @mdc-berlin.bsky.social such a great idea πŸ™ˆ

01.12.2025 16:08 πŸ‘ 2 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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The fall of a prolific science journal exposes the billion-dollar profits of scientific publishing One of the 15 publications that put out the most studies globally has been expelled from the indexing system for irregularities. Its publisher, Elsevier, has a 38% profit margin that reached $1.5 bill...

Interesting investigation into a dodgy Elsevier journal -- with the additional nugget that the CEO of Elsevier's parent company made more than €15 million in total compensation last year.

english.elpais.com/science-tech...

28.11.2025 20:51 πŸ‘ 90 πŸ” 60 πŸ’¬ 3 πŸ“Œ 21

lower bar for scientific reports πŸ₯²

28.11.2025 08:46 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Join us for an MDC Afternoon for Immunology at the @mdc-bimsb.bsky.social on December 8th with student/postdoc talks and two keynotes, Jeffrey A. Hubbell and Stefano Casola πŸ™‚

πŸ”— Register: www.mdc-berlin.de/news/events/...

27.11.2025 09:24 πŸ‘ 2 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

Effects of butyrylated high amylose maize starch (HAMSB) as an adjuvant for oral immunotherapy https://www.medrxiv.org/content/10.1101/2025.09.11.25335560v1

15.09.2025 02:55 πŸ‘ 0 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

I want to know if Th2-MPP cells could be found in the gastrointestinal biopsies… (www.nature.com/articles/s41... ), besides that, a nice study in line with what our group published recently! :)

22.11.2025 16:34 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Also today at #PreprintHub1, Frederika Rentzeperis from Mt.Sinai will present a #preprint by Xueping Zhu from Professor Sokol's lab on how "Sensory neuronal mTORC1 signaling establishes neuroimmune memory that initiates allergic immunity"

www.biorxiv.org/content/10.1...

19.11.2025 06:59 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

featuring Thetis cells! (I should go to sleep)

18.11.2025 21:05 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

A cool study + it was so nice to write this highlight with @theonlylabever.bsky.social πŸ₯•

11.11.2025 21:02 πŸ‘ 3 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

🚨#job alert 🚨
I am recruiting a technician and #postdoc in #bioinformatics to investigate T cell transcription networks in skin and gut #inflammation. We are a growing and diverse team at @ubcmedicine.bsky.social. Links below:
tinyurl.com/42w4vh7s
tinyurl.com/4n5wva6c
Please repost #immunosky

31.10.2025 15:33 πŸ‘ 4 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

)))

31.10.2025 10:14 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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halloween costume this year #academia

30.10.2025 16:44 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Flexible and rapid validation of structural variation using adaptive sampling Identification of genomic rearrangement by microarrays or short-read sequencing frequently lacks information about the exact architecture and breakpoints of variants due to technical limitations. Inde...

please submit preprints, this small study showing what adaptive sampling (AS) by #ONT can do helped me to compare my own results and *perhaps* improve them very soon. actually, AS is probably the best way to do targeted sequencing with long reads. www.researchsquare.com/article/rs-7...

17.10.2025 14:22 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0