Guigó Lab

Wonderful to have David Duffy with us last week! Lots of new biodiversity genomics and eDNA approaches in the making ... 🧬🐢🌦️ @crg.eu @prbb.org @ufresearch.bsky.social

Fa 25 anys, el Projecte Genoma Humà sortia als informatius… i avui TV3 ens recorda aquell moment amb una joia d’arxiu: la entrevista a en Roderic i en Pep quan es va publicar a Nature i Science.

🧬 Aquest any es compleixen 25 anys d’un moment clau per a la ciència: la publicació de la primera seqüència del genoma humà. Un projecte col·laboratiu a escala mundial amb la participació dels investigadors Pep Abril i @rodericguigo.bsky.social @crg.eu

www.3cat.cat/3cat/25-anys...

Fa 25 anys de la publicació de la primera seqüència del genoma humà, un esforç internacional que va tenir aportació catalana, amb els investigadors Pep Abril @geneticsub.bsky.social i Roderic Guigó @crg.eu

Podeu consultar la notícia completa al 3cat:
www.3cat.cat/3cat/telenot...

Exactly 25 years ago, @rodericguigo.bsky.social and his PhD student published the first draft of the human genome in Science. The Catalan researchers were the only two from all Spain that took part. Here they are reflecting on the huge scientific feat: www.crg.eu/en/news/25-y...

This weekend marks the 25th anniversary of the publication of the human genome. Read @rodericguigo.bsky.social memories of the event here: www.crg.eu/en/news/25-y...

Los dos españoles dentro del mayor proyecto de biomedicina de la historia: “Con Trump, no sería posible” Pep Abril y Roderic Guigó compusieron el primer mapa del genoma humano hace un cuarto de siglo. El megaproyecto internacional no ha traído aún una esperada revolución en medicina, pero ha cambiado la ...

Pep Abril y @rodericguigo.bsky.social dentro del mayor proyecto de biomedicina denla historia hace un cuarto de siglo elpais.com/ciencia/2026...

Nou Recerclip. La llista de reproducció del cos: l'Andreu Juanola va al Centre de Regulació Genòmica YouTube video by Recerca i Universitats

🔬🧬 Nou #Recerclip publicat! La recerca del @crg.eu, presentat per l'Andreu Juanola.

Podeu descobrir diversos projectes, com ara #PyriSentinel 🏔️ @hannahbenisty.bsky.social

youtu.be/MQv6-InbREs

@crg.eu @prbb.org @cerca.cat @bist.eu
#POCTEFA #Interreg

El sesgo europeo en los mapas genéticos entorpece la investigación biomédica Los mapas de expresión de los genes están dominados por datos de individuos de ascendencia europea y presentan importantes lagunas de información sobre el resto del mundo

Conocer la variabilidad genética de todo el mundo acaba beneficiando a todo el mundo. Lo cuenta Michele Catanzaro en El Periódico después de que un estudio coliderado por @rodericguigo.bsky.social descubrió y cuantificó las lagunas en los mapas genéticos.

@rodericguigo.bsky.social (@crg.eu) i @tmarquesbonet.bsky.social (@ibe-barcelona.bsky.social - @cnag-eu.bsky.social) membres de la CBP participaran en la commemoració dels 25 anys del Projecte Genoma Humà aportant una mirada experta sobre genòmica, biodiversitat i futur de la recerca
👇

Long-read transcriptomics of a diverse human cohort reveals ancestry bias in gene annotation - Nature Communications Current human gene annotations are predominantly based on individuals of European ancestry. Here, the authors use long-read RNA sequencing across diverse human populations to reveal ancestry-specific ...

Thrilled to share! 🧬🌍 Our 800M+ long-read RNA-seq dataset from 8 diverse populations reveals big gaps in gene annotations for non-European transcripts. Let’s build global inclusive annotations.

@bsc-cns.bsky.social @crg.eu
@melelab.bsky.social

www.nature.com/articles/s41...

Long-read transcriptomics of a diverse human cohort reveals ancestry bias in gene annotation - Nature Communications Current human gene annotations are predominantly based on individuals of European ancestry. Here, the authors use long-read RNA sequencing across diverse human populations to reveal ancestry-specific ...

Human gene maps contain major blind spots that leaves out a vast majority of the world's biological diversity, according to a new study led by the CRG's @rodericguigo.bsky.social with @bsc-cns.bsky.social. The researchers uncovered tens of thousands of new transcripts and entirely new genes.

📣 Yesterday our study uncovering the ancestry bias in gene annotations was finally published in @natcomms.nature.com!
www.nature.com/articles/s41...

If you work in human genetics or transcriptomics, do not miss our tweetorial!👇

@guigolab.bsky.social @bsc-cns.bsky.social @crg.eu

Our annual PhD call is closing at the end of this week on 30 November. If you're interested in carrying out world-class scientific research in Barcelona, you still have a few days left to submit your application! www.crg.eu/en/content/t...

📢🎓Join our lab at @crg.eu through the International PhD Programme!

We’re looking for a student motivated to uncover the rules of genome architecture through bioinformatics and machine learning 🧬💻

🔵Apply here: www.crg.eu/en/content/t...

Avui hem obert les portes de la nostra recerca als visitants de l’ #OpenPRBB 🔬🪰🧬 Sempre amb molta il·lusió! @crg.eu @prbb.org

Happy to share the Biodiversity Cell Atlas white paper, out today in @nature.com. We look at the possibilities, challenges, and potential impacts of molecularly mapping cells across the tree of life.
www.nature.com/articles/s41...

🌍✨ Master’s project in our Lab @crg.eu
🌱🧬 Help build the Biodiversity Long-Read Transcriptomic Catalogue @ebpgenome.bsky.social with @pacbio.bsky.social & @nanoporetech.com

💻 Python/R, Linux, seq data
💶 600€/mo + travel
📩 fabio.zanarello@crg.eu / roderic.guigo@crg.eu
ℹ️ www.crg.eu/en/content/t...

🚨 We are hiring a Postdoc @crg.eu! 🧬

Within the EU-funded #PrecisionTox project. We are developing computational methods to predict toxicity by integrating RNA-seq data from humans and model species 🪱🪰🐸🐠. The project will help replace animal testing.

🔗 Apply now: recruitment.crg.eu/content/jobs...

🎉 We’ve earned Bronze LEAF Accreditation for our efforts to make lab work more sustainable @crg.eu! By joining @ucl.ac.uk Laboratory Efficiency Assessment Framework, we are committed to improving efficiency and reducing our environmental impact. 🌱🔬

🎓 Huge congrats to our two @bist.eu Master’s students, Igor Trujnara and @rebeccawallis.bsky.social who successfully defended their theses this week!

🧬💻Igor explored Large Language Models for genome annotation, while Rebecca investigated microbial biodiversity in Pyrenean lakes🏔️.

@crg.eu @upf.edu

🚴🏻🚴🏻‍♀️🚴🏻‍♂️ Read about Ana, Fabio & Nadja’s journey to the LongTREC Summer School in Norwich!
#LongTREC #ScienceOnTheMove #SustainableScience #Bioinformatics #ScienceLife

Great to see our PhD student Fabio Zanarello sharing his work yesterday at LongTREC summer school!
#LongReadsTranscriptomics #LongTREC #GenomeAnnotation #Bioinformatics #EarthBioGenomeProject
@crg.eu

We made it!!!! València-London by train. London-Norwich by bike!!!

First journey done! 🌟 Our amazing cyclists arrived safely in Cambridge — still smiling! 😄🚴‍♀️ More than the ride: sustainability, team spirit & pushing limits. They’re recharging now… and ready for the next leg! #LongCyclingForScience #TeamSpirit
@anaconesa.bsky.social #LeadingByExample

Not everyone can or wants to cycle for 2–3 days, but we can all take a moment to ask ourselves:

💡 “How much am I impacting the planet with this trip?”
💡 “What can I do to reduce that impact?”

@anaconesa.bsky.social

#LongCyclingForScience #SustainableScience #LongReadsTranscriptomics

🚴 From @crg.eu to the roads of Europe, our PhD student Fabio and the #LongTREC team are combining cutting-edge science with sustainable travel.

Now in London, and heading next to Cambridge! #LongCyclingForScience

🚴‍♂️🌍 Excited to see our PhD student Fabio Zanarello featured in the #LongTREC video series! 👏

Don’t miss the video and learn more about #LongTREC #LongReadsTranscriptomics and #LongCyclingForScience.

#SustainableScience #Bioinformatics #PhDLife

@crg.eu

This is going to be so much fun!!! Do not miss our #LongCyclingForSciene adventure! from Valencia to Norwich by train & bike, posting about science and bcsustainability @pacbio.bsky.social @nanoporetech.com @iscb.bsky.social @csic.es @hitseq.bsky.social @bcbhubcsic.bsky.social @sebibc.bsky.social

Studying relative RNA localization from nucleus to the cytosol Abstract. The precise coordination of important biological processes, such as differentiation and development, relies heavily on the regulation of gene exp

📊 RNA localization matters for gene regulation. We present a method to estimate transcript distributions between nucleus & cytosol using nuclear, cytosolic and whole-cell RNAseq.

🔵🧬 doi.org/10.1093/narg...

@crg.eu @rodericguigo.bsky.social