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Eftychis Frangedakis

@e-frangedakis

SynBryo Group @OIST, Japan https://synbryo.weebly.com/ Plant Synthetic Biology 🌱 - EvoDevo 🏺 - Chloroplast β˜€οΈ - Hornworts πŸ¦„

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17.02.2026
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Latest posts by Eftychis Frangedakis @e-frangedakis

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Never outdated: 12 timeless tips for effective leadership.
blog.venturemagazine.net/12-tips-for-...

27.02.2026 07:24 πŸ‘ 26 πŸ” 9 πŸ’¬ 0 πŸ“Œ 0
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a black and white photo of a train with the caption " all aboard the hypocritical hate train !! " ALT: a black and white photo of a train with the caption " all aboard the hypocritical hate train !! "

We always hear the horror stories after someone falls from grace. Where were all the tenured academics before it got that far?

27.02.2026 09:50 πŸ‘ 12 πŸ” 2 πŸ’¬ 1 πŸ“Œ 1

Now online in its final version. Plz surf to doi.org/10.1111/tpj....

12.11.2025 21:29 πŸ‘ 37 πŸ” 18 πŸ’¬ 0 πŸ“Œ 2

We’re excited to expand access to genetic engineering tools for plants, this time with a focus on the early land plant model Marchantia 🌱

Thank you to the Haseloff lab for depositing this kit with us!

26.02.2026 18:38 πŸ‘ 7 πŸ” 4 πŸ’¬ 0 πŸ“Œ 0
Addgene: OpenPlant Kit Use the OpenPlant toolkit for genetic engineering of the plant synthetic biology model Marchantia polymorpha.

The OpenPlant kit is finally available from Addgene as... a kit :)
www.addgene.org/kits/haselof...
@addgene.bsky.social #marchantia #synbio

26.02.2026 01:08 πŸ‘ 25 πŸ” 10 πŸ’¬ 0 πŸ“Œ 1
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Moss Medicines: The Next Revolution in Biotech? Plant biotechnologists are favoring moss factories over other models to produce certain valuable proteins.

Moss Medicines: The Next Revolution in #Biotech?
Plant biotechnologists are favoring #moss factories over other models to produce certain valuable #proteins.
Great article based on an interview with yours truly.
www.the-scientist.com/moss-medicin...

25.02.2026 09:23 πŸ‘ 18 πŸ” 5 πŸ’¬ 1 πŸ“Œ 1
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Joanna Wilbraham's Mosses, Liverworts, and Hornworts of the World is a magnificently illustrated guide to the bryophyte species found across the world.

Out now! Learn more and explore a free sample: press.princeton.edu/books/hardco...

17.08.2025 15:08 πŸ‘ 11 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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πŸš€ Excited to launch the #OpenCloning Assembler!

🧬 Built to demystify Golden Gate for beginners and save time for experts -> MoClo assembly blazing fast ⚑

✍️ Use existing syntaxes or design your own!

#SynBio #GoldenGate #MoClo #OpenSource #Biotech

πŸ‘‰ Try it: app.opencloning.org

Feedback welcome!

20.02.2026 12:54 πŸ‘ 32 πŸ” 14 πŸ’¬ 4 πŸ“Œ 4
Graphic recording of the workshop session. Key words, messages and topics covered are grouped by speaker(s). This visual summary is intended to capture the essence of the session, it obviously cannot resolve or explore in detail all the complex issues listed.
The illustration was commissioned to the illustrator Zsofi Lang.
"Building a diverse and inclusive community through effective teaching and mentoring"

Graphic recording of the workshop session. Key words, messages and topics covered are grouped by speaker(s). This visual summary is intended to capture the essence of the session, it obviously cannot resolve or explore in detail all the complex issues listed. The illustration was commissioned to the illustrator Zsofi Lang. "Building a diverse and inclusive community through effective teaching and mentoring"

Super excited to have this online at @jxbotany.bsky.social doi.org/10.1093/jxb/...
"Building a diverse and inclusive plant science community," a call-to-action. Thanks to @apaterlini.bsky.social
@mehta-lab.com @yoselin.bsky.social
@goormachtig.bsky.social & Agnes Uhereczky + funders!πŸ’š

09.02.2026 12:52 πŸ‘ 39 πŸ” 25 πŸ’¬ 0 πŸ“Œ 1
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One of my favorite transposon facts. Think LTR retrotransposons are a homogeneous group? The two main kinds -- Ty1 and Ty3 -- are as evolutionary diverged as GIANT SQUID and PINE TREES.

18.02.2026 16:54 πŸ‘ 46 πŸ” 8 πŸ’¬ 2 πŸ“Œ 0
Z-stack photo of an Anthoceros agrestis sporophyte with stomata all along the structure.

Z-stack photo of an Anthoceros agrestis sporophyte with stomata all along the structure.

"We found an arabidopsis mutant developing stomata on the roots!"

Not buying it? Eggcellent! What you actually see is a horn of the hornwort Anthoceros agrestis (and what you read was probably my favorite 1st April joke we did in the lab).

04.12.2024 17:35 πŸ‘ 5 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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Marchantia Workshop 2026 News

International Marchantia Workshop 2026

Nov. 27th – 29th, 2026
Kobe, Japan

sites.google.com/view/marchan...

28.11.2025 12:51 πŸ‘ 11 πŸ” 10 πŸ’¬ 0 πŸ“Œ 0
Image features photo of Marie Clark Taylor

Image features photo of Marie Clark Taylor

Botanist Marie Clark Taylor transformed plant science education, modernizing curricula, advancing microscopy, and mentoring generations of scientists at Howard University. πŸ”¬

#BlackHistoryMonth #PlantScience

17.02.2026 17:15 πŸ‘ 11 πŸ” 4 πŸ’¬ 0 πŸ“Œ 0
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Regulation of Chloroplast Biogenesis and Differentiation Abstract. Chloroplasts are semi-autonomous organelles essential for photosynthetic organisms. They derived from ancestral cyanobacteria through an endosymb

Very happy this review is out 😊🌱
I've collected recent advances in transcriptional and epigenetic 🧬 Regulation of Chloroplast Biogenesis and Differentiation url: academic.oup.com/jxb/article/...

08.12.2025 12:23 πŸ‘ 18 πŸ” 10 πŸ’¬ 2 πŸ“Œ 0

So cool!

17.02.2026 13:09 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Marchantia might seem an unlikely biotech crop, but it’s worth trying. In Aurore’s thesis, we pushed this concept by engineering the auronidins with MpMYB14 and using the pigments to dye cotton. It ended up giving a very unique and beautiful product. #PlantScience www.biorxiv.org/content/10.6...

16.02.2026 15:38 πŸ‘ 58 πŸ” 19 πŸ’¬ 1 πŸ“Œ 3
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our hornwort paper got the cover of the @newphyt.bsky.social
nph.onlinelibrary.wiley.com/doi/10.1111/...

08.01.2026 14:59 πŸ‘ 55 πŸ” 12 πŸ’¬ 0 πŸ“Œ 1
Fig. 1.Schematic diagram of tRNA-gRNA multiplexing for plant genome editing. (A) A plasmid is constructed containing a tRNA-gRNA cassette driven by the U6 promoter, together with a transcription unit for Cas9 expression. (B) After transformation into the plant, the primary RNA transcript is cleaved by the endogenous tRNA-processing enzymes RNase P and RNase Z, resulting in functional guide RNAs for genome editing.

Fig. 1.Schematic diagram of tRNA-gRNA multiplexing for plant genome editing. (A) A plasmid is constructed containing a tRNA-gRNA cassette driven by the U6 promoter, together with a transcription unit for Cas9 expression. (B) After transformation into the plant, the primary RNA transcript is cleaved by the endogenous tRNA-processing enzymes RNase P and RNase Z, resulting in functional guide RNAs for genome editing.

βœ‚οΈπŸ§¬ EDITOR’S CHOICE πŸ§¬βœ‚οΈ

Frangedakis et al. present an improved method for generating complex CRSIPR-mediated genome modifications in Marchantia polymorpha using the tRNA-gRNA approach together with an optimized protocol for thallus transformation.

πŸ”— doi.org/10.1093/jxb/...
#PlantScience πŸ§ͺ

16.01.2026 16:00 πŸ‘ 12 πŸ” 6 πŸ’¬ 2 πŸ“Œ 0
Construction of the two-component Stomatal XVE system: stomatal lineage-specific XVE lines and effector vectors.

Construction of the two-component Stomatal XVE system: stomatal lineage-specific XVE lines and effector vectors.

A toolkit for cell-stage-specific gene perturbation in stomatal development

Kou et al. @onsunlau.bsky.social

nph.onlinelibrary.wiley.com/doi/10.1111/...

17.02.2026 10:27 πŸ‘ 6 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0