Jack C. Leo's Avatar

Jack C. Leo

@jackcleo

Molecular microbiologist working at the Department of Biosciences, Nottingham Trent University. Research interests include molecular pathogenesis and bacterial adhesion mediated by autotransporter proteins of Gram-negative bacteria. Opinions are my own.

22
Followers
32
Following
6
Posts
13.07.2025
Joined
Posts Following

Latest posts by Jack C. Leo @jackcleo

Post image Post image

Lots of microbiology-related activities organised by @arom-ntu.bsky.social members at the Festival of Science and Curiosity in Nottingham.

17.02.2026 10:33 πŸ‘ 2 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
Mutations affecting the Ξ²-sheet at the extracellular opening of the intimin Ξ²-barrel domain lead to reduced protein levels and inefficient passenger secretion Abstract. Attaching and effacing pathogens, such as enteropathogenic and enterohaemorrhagic Escherichia coli, rely on an adhesin, intimin, for attachment to enterocytes and downstream effects leading ...

Very happy to see this paper finally published! Congrats to Priya and our German collaborators - it took a while, but here it is! portlandpress.com/bioscirep/ar...

09.02.2026 18:44 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
Biotechnology and Biological Sciences Doctoral Training Programme - The University of Nottingham

PhD studentships available through our BBSRC-funded doctoral programme.

πŸ¦ πŸ§«πŸ’» Contact me if you're interested in using bioinformatics/lab-based approaches with cultivated and uncultivated bacteria of the human microbiome, to identify and characterize novel enzymes with potential biotech applications.

22.01.2026 20:58 πŸ‘ 8 πŸ” 15 πŸ’¬ 1 πŸ“Œ 0
Preview
Characterising antibacterial toxins in the food-borne pathogen Listeria monocytogenes at Newcastle University on FindAPhD.com PhD Project - Characterising antibacterial toxins in the food-borne pathogen Listeria monocytogenes at Newcastle University, listed on FindAPhD.com

www.findaphd.com/phds/project... interested in bacterial antagonism? PhD opportunity in our team, see below. Please repost!

23.01.2026 10:33 πŸ‘ 22 πŸ” 31 πŸ’¬ 1 πŸ“Œ 2
Optimising the use of alternative therapies for the treatment of urinary infections - The University of Nottingham

🚨 Fully‑funded PhD for Home Students🚨

We'll explore non-antibiotic alternatives in relatistic environments, uncovering how they work, if they affect antibiotic activity and whether they influcence AMR acquistion. Come join a wonderful supervisory team!

#MicroSky #UTISky #AMar

tinyurl.com/38u552bu

21.01.2026 21:12 πŸ‘ 5 πŸ” 10 πŸ’¬ 1 πŸ“Œ 3
Post image

I’m thrilled to have been awarded the Addgene Blue Flame award for sharing the Omp-deficient strains that we developed a few years ago in Oslo. Thanks @addgene.bsky.social!

16.01.2026 12:06 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 1

Huge congratulations to Lena! πŸ‘

08.01.2026 13:44 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Preview
Chain formation mediated by Escherichia coli immunoglobulin-binding proteins EibD and EibG depends on expression levels and localization of proteins - Scientific Reports Scientific Reports - Chain formation mediated by Escherichia coli immunoglobulin-binding proteins EibD and EibG depends on expression levels and localization of proteins

I’m thrilled to see our latest paper on chain formation mediated by trimeric autotransporters published. This was a collaboration with @schauflerlab.org; most of the data was produced by Lena Swiatek during a 3-month scientific visit at NTU - way to go Lena! www.nature.com/articles/s41...

13.10.2025 08:52 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

A new preprint from my group, representing the PhD work of Rachael Duodu. Thanks to @bugsinyourguts.bsky.social for transcriptomics analysis!

17.09.2025 05:44 πŸ‘ 1 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
Preview
Lecturer in Medical Bioscience at Nottingham Trent University Start your UK & international job search for academic jobs, research jobs, science jobs and managerial jobs in leading universities and top...

Lecturer in Medical Bioscience at Nottingham Trent University. #jobs #microsky

Covering topics including:
Infectious disease;
Clinical and molecular microbiology;
Mechanisms of drug action and therapeutic innovations.

Contact @jodywinter.bsky.social for full details.

28.08.2025 20:12 πŸ‘ 0 πŸ” 5 πŸ’¬ 0 πŸ“Œ 0