It was fun working on this project, and I am grateful to my collaborators Kate Bostock, Ramanarayanan Kizhuttel, Maciej Bak and especially my Master Thesis supervisor and mentor @robjohnnoble.bsky.social
It was fun working on this project, and I am grateful to my collaborators Kate Bostock, Ramanarayanan Kizhuttel, Maciej Bak and especially my Master Thesis supervisor and mentor @robjohnnoble.bsky.social
And if you are curious about the βbehind the sceneβ story of the paper, from conception to publication, have a look at this blog post: communities.springernature.com/posts/on-the...
You can find some highlights of the paper in this blog post: mathematical-oncology.org/blog/selecti...
Our paper "Selective sweep probabilities in spatially expanding populations" is out in Nature Communications!
Our work extends the theory of population genetics and contributes to our understanding of cancer evolution.
doi.org/10.1038/s414...
Academics often lament that hardly any masterβs projects get published. The student moves on. Other research takes priority. No one has time to do the final analyses. Here I tell how one masterβs project was, through persistent teamwork, finally carried over the finish line: go.nature.com/4aKs7N3
An incredible opportunity for early career researchers - Imperial's Faculty of Medicine is hiring 20 Assistant Professors!
If youβre interested in machine learning and mathematical modelling, weβre recruiting a PhD student to develop new methods for studying cancer evolution at
@imperialimmuno.bsky.social
www.findaphd.com/phds/project...
Screenshot of Job Ad
EMBL site in Heidelberg
Zurich, incl. a bit of UZH/USZ
Job offer: PhD-level biostatistician with ML&omics experience to work on prediction models for CAR T cell therapy, in an exciting clinical trial - spatial omics - data science consortium (LOOP/INTeRCePT3.0 centered in Zurich; this position in Heidelberg)
embl.wd103.myworkdayjobs.com/en-GB/EMBL/j...
𧬠We're hiring a postdoc!
Come chart somatic evolution with us using cutting-edge long-read & single-cell tech π¬
Computational bio background + love for complex cancer genomics = perfect fit
π Leuven, Belgium π§ jobs.vib.be/j/129915/
#postdoc #genomics #hiring
We're excited to be recruiting an NIH funded postdoc to work in the Coop lab at UC Davis. We're specifically interested in candidates who are want to work at the intersection of human genetics, GWAS, and population genetics modeling. Please RT
Open postdoc position in our lab @icr.ac.uk to develop a cfDNA test for #early detection of colorectal #cancer in inflammatory bowel disease #IBD:
jobs.icr.ac.uk/vacancies/14...
It's bench-to-bedside research, translating biology of pre-cancer evolution.
Funded by @bowelcanceruk.bsky.social
My supervisor, Jonas Demeulemeester (@jdemeul.bsky.social), is hiring a Postdoc to study Cancer Genomics at the VIB-KU Leuven Center for Cancer Biology: jobso.id/pbgr
Cool projects, great team, and super working environment in general! Check it out!
Do you like theoretical biology, mathematical&conceptual modelling and want to apply yourself to cutting-edge research at all levels of biology, from molecules to ecosystems?
Come to EMBL! Scope includes physics-based models, emergence, statistics, ML/AI
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
Excited to announce that registration for the 13th
@mathonco.bsky.social workshop on Treatment Revolution is now open. Held onsite @moffittnews.bsky.social Nov 2-Nov 7 #MoffittIMO more details: imo13.eventbrite.com. Deluxe travel awards are available on a competitive basis, apply by 10/03!
Studying cancer evolution needs multi-region or single cell seq for phylogenetics, right? Amazingly (I think!) we found single-sample bulk methylation suffices, via analysis of "fluctuating methylation". In @nature.com today led by brilliant @calumgabbutt.bsky.social www.nature.com/articles/s41...
Long-read single-cell genome, transcriptome and open chromatin profiling links genotype to phenotypes. https://www.biorxiv.org/content/10.1101/2025.09.08.674950v1
Darwin's famous sketch of a rooted tree, representing speciation
New preprint! Let me tell you a story about trees, caterpillars, brooms, entropy, and getting scooped by 50 years.
Rooted trees of all shapes and sizes crop up all over biology, computing and elsewhere. How can we best compare the shapes of these myriad trees? 1/14
arxiv.org/abs/2507.08615
In #GENETICS, @alexsteinresearch.bsky.social⬠and @benjaminwerner.bsky.social⬠present a new study about the population genetics of cancer. Learn about their theoretical assessment of the genetic makeup of cancers before and after treatment: buff.ly/AE4sLUH
Interested in population genetics of cancer?
If so, have a look at our manuscript accepted by @genetics-gsa.bsky.social, in which we provide a theoretical assessment of the genetic makeup of cancers before and after treatment!
My department is hiring! Permanent faculty job (research + teaching) in applied maths. Mathematical biology would be highly appropriate. We're a friendly department in a large university in central London, recently merged with a big medical school. Apply by 1st June. www.jobs.ac.uk/job/DMY889/l...
Thank you David @cancerevo.org and Simone @zaccasimo.bsky.social for building my PhD viva panel! I enjoyed the discussions and appreciate your time and effort to assess my PhD.
And heartfelt thank you Ben @benjaminwerner.bsky.social and Katerina for guiding me through this PhD journey!
Congratulations to a successful viva Dr. @alexsteinresearch.bsky.social
Many thanks to @cancerevo.org and @zaccasimo.bsky.social to be examiners!
The University of Bern is looking for a Tenure Track Assistant Professor in Mathematical or Computational Biology: www.nature.com/naturecareer...
Congrats to all of you! π₯³
We have an open #PhD #studentship as part of our "Black Leaders in Cancer" programme at @crukconvergence.bsky.social & @icrlondon.bsky.social. About computational modelling of T-cell evolution in cancer. www.findaphd.com/phds/project... I'm looking forward to meeting prospective students #CRUKfunded
πNew Author's summary about
"Complexity-stability relationships in competitive disordered dynamical system" O Mazzarisi, M Smerlak
and
"Diversity begets stability: Sublinear growth and competitive coexistence across ecosystems" I Hatton, O Mazzarisi, A Altieri, M Smerlak
Resharing here a recent X post. In this preprint, we introduce an improved version of NanoSeq, a duplex sequencing protocol with <5 errors per billion bp in single DNA molecules, and use it to study the somatic mutation landscape of oral epithelium in >1000 people. 1/ www.medrxiv.org/content/10.1...
Alex just dropped his magnus opus on BioRxiv
scholar.google.com/citations?vi...