Christine Cucinotta

These Famous Black Inventors Probably Changed Your Life. Here’s What to Know About Their Creations. Madam C.J. Walker, Mark Dean, and Patricia Bath are just a few Black inventors who have made life easier.

STEM Black History Facts 13/28

Otis Boykin improved electrical components used in pacemakers, increasing the reliability of lifesaving implantable medical devices.

this is awesome - really nice work and congrats!!!

🎉 LEE LAB PAPER ANNOUNCEMENT for this month's issue of #GENETICS! We're celebrating from both coasts, bc after defending her MS in 2024, Deepshi's now a biotech researcher in the Bay Area.

tl;dr: nucleosome remodeling is necessary to repair germline DNA damage 🧬
academic.oup.com/genetics/art...

I think that, like with art, papers offer an opportunity for you to tell the story your own way. Could another person research the same question? Yes. However, each person has the opportunity to do it and communicate it in their own way, and we must protect that 🧪

Let’s make it viral folks. Thank you @histoftech.bsky.social.

Live-cell single-molecule dynamics of eukaryotic RNA polymerase machineries Eukaryotic gene expression is orchestrated by RNA polymerases (RNAPI, II, and III) and associated factors, yet their real-time dynamics remain obscure. Using single-molecule tracking in living yeast, ...

🧬🔬🎥 @science.org Live-cell single-molecule dynamics of eukaryotic RNA polymerase machineries | Science www.science.org/doi/10.1126/...

We asked whether principal investigators have plans in place for how research can continue without them Researchers must be mindful of unexpected events that may leave them incapacitated or unable to lead their research projects or labs.

So the question here is mis-specified. There is no "alternative" research funding in any way that would make American biomedical research whole for researchers to seek out. 1/ www.statnews.com/2026/02/03/p... via @statnews.com

More attention here, please.

Terrific paper on a new chromosomal
compartment where extensive loop
extrusion isolates domains from
other such domains

Congrats!!! 🤩

Karolin Luger - Vilcek Foundation Karolin Luger's research led to the capture of a high resolution image of chromatin, resulting in the development of innovative drug treatments for diseases like cancer.

Unquestionably the result of combined effort from all current and former lab members, support from colleagues @CSU and @CU, and support from @hhmi-science.bsky.social and NIH over decades. A heartfelt 🙏 to my nominators and of course @vilcekfoundation.bsky.social.
vilcek.org/prizes/prize...

excellent thread

Everyone who tut-tuts co-workers concerned about their job and health insurance should probably include some info on their own household finances, retirement situation and health conditions, current and anticipated.

Join our virtual seminar!

@sedonamurphy.bsky.social presents cutting-edge research on 3D genome organisation & epigenetic memory in development, moderated by @stefanschoenfelder.bsky.social

📅 Jan 8, 4pm UK
💻 Zoom

Register: us02web.zoom.us/webinar/regi...

#3DGenome #Epigenetics #ChromatinBiology

Can someone please respond to Stephen Miller with this message from Frank Sinatra?

Please folks. Learn the history.

My lab is hiring a postdoc (ERC funded)! If you're interested, get in touch!

An integrated view of the structure and function of the human 4D nucleome - Nature The 4D Nucleome Project demonstrates the use of genomic assays and computational methods to measure genome folding and then predict genomic structure from DNA sequence, facilitatin...

A major output of the 4D Nucleome project appeared today. This is the joint effort of many scientists working together and (publicly) sharing data and results for several years. We hope this is of interest to many genome biologists!

www.nature.com/articles/s41...

im maxed out on my ssri after only half a semester 💀

Dynamic evolution of EZHIP, an inhibitor of the Polycomb Repressive Complex 2 in mammals The Polycomb Repressive Complex 2 (PRC2) is an ancient, conserved chromatin-interacting complex that controls gene expression, facilitating differentiation and cellular identity during development. It...

@pravrutharaman.bsky.social got super intrigued about EZHIP/CATACOMB, previously identified as a histone H3K27M mimic of PRC2. You can read about her efforts here: www.biorxiv.org/content/10.6... We hope these analyses will help spur more analyses in this very cool gene! 1/

Confused by all the histones that are cropping up in organisms that are decidedly NOT eukaryotes? check out our review - fantastic work by team NucEvo in the #Lugerlab
The Expanding Histone Universe: Histone-Based DNA Organization in Noneukaryotic Organisms - www.annualreviews.org/content/jour...

we need to make science culture better. for Zara. we should keep her legacy going forever

first met Zara at an Opeth show when we were both phd students. she had the best taste in music. I'll think of her every time i listen to Opeth for nostalgia, Sleater-Kinney (ofc), and basically any good music. time to go back thru her 5x5s

i knew she was sick and still it is a shock. i miss her so much

coming up for air after long periods of major depression feels like whiplash. late to the horrible news of our loss of Zara Weinberg.

at a loss for words but she was one of the most amazing people i’ve known. brilliant. empathetic. making a huge difference in the world. i will miss her terribly.

Release Release v0.1.8 · quinlan-lab/bedder-rs Changes in v0.1.8 Downloads bedder-static-linux-x86_64: Static binary for Linux x86_64 (no dependencies required) bedder-static-macos-x86_64-python3.13: macOS x86_64 binary built with Python 3.13 ...

Get bedder v0.1.8 and r𝗲𝗮𝗱 𝘁𝗵𝗲 𝗱𝗼𝗰𝘂𝗺𝗲𝗻𝘁𝗮𝘁𝗶𝗼𝗻 here: github.com/quinlan-lab/...

We are looking for researchers to kick the tires, integrate bedder into their pipelines, and provide feedback on the Python functions, performance, and overall user experience! Please share and give us your feedback.

We are thrilled to announce the first official release (v0.1.8) of #𝗯𝗲𝗱𝗱𝗲𝗿, the successor to one of our flagship tool, #𝗯𝗲𝗱𝘁𝗼𝗼𝗹𝘀! Based on ideas we conceived of long ago (!), this was achieved thanks to the dedication of Brent Pedersen.

1/n

Blocking ferroptosis to expand human HSCs Nature Cell Biology - Haematopoietic stem cells (HSCs) are used in a variety of cellular therapies, but our ability to support these cells ex vivo remains technically challenging. A new study...

Truly enjoyed writing this piece about recent discoveries by @bloodgenes.bsky.social and colleagues about how we can improve HSC expansion & gene editing by blocking ferroptosis!

Our @natcellbio.nature.com N&V: rdcu.be/eR25t
Associated article: tinyurl.com/msf9x8fn

AI is good at needling people, had me in stitches following this thread!

the best thing ever is when the person you are writing a letter for makes calendar invites for you for the deadlines