Robert Grosse @ grosselab's Avatar

Robert Grosse @ grosselab

@grosselab

all things cytoskeleton - nuclear actin dynamics and genome - nucleoskeleton and nuclear organisation - cancer cell invasion and pharmacology @University of Freiburg

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Latest posts by Robert Grosse @ grosselab @grosselab

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Deltaviruses spread through a viral Trojan Horse Hepatitis D-like satellite viruses, known as deltaviruses, have been recently discovered in a wide range of animals. These viruses are thought to expr…

The Trojan Horse is real, and it’s microscopic! 🐴🦠
Our paper is out today in @cellcellpress.bsky.social!
We discovered that deltaviruses physically hide INSIDE helper viruses to sneak into new cells. And to prove it, we had to image them from every angle. 🧵👇

www.sciencedirect.com/science/arti...

07.03.2026 12:36 👍 70 🔁 29 💬 4 📌 1
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🚨 Job Alert - Please share! 🙏

Interested in 3D gene regulation in development & evolution? 🤓🧬

💥 Our lab at @cabd-upo-csic.bsky.social is expanding!

We’re recruiting:
✅ PhD students
✅ Postdocs
💻🧪 Experimental or computational backgrounds welcome

👇 Details below

06.03.2026 10:14 👍 22 🔁 20 💬 1 📌 4
The wonderful historic city of Marburg

The wonderful historic city of Marburg

🚨 University Marburg (Germany) is recruiting a W2 Professor of Mol. Pharmacology in the Faculty of Medicine.

Focus areas: Epithelial adaptation in #inflammation, #regeneration, and/or #cancer

stellenangebote.uni-marburg.de/jobposting/0...

#AcademicJobs #Pharmacology #FacultyPosition #cellbio

05.03.2026 11:39 👍 20 🔁 18 💬 0 📌 0
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🚨 #postdoc to be hired in the Paluch Lab 🚨

If you know anyone experienced with and, more importantly, excited about nanoscale architecture of #actincortex and super-res & electron #microscopy do encourage them to apply👇

Amazing colleagues, can only recommend 😉

www.cam.ac.uk/jobs/researc...

03.03.2026 15:50 👍 12 🔁 12 💬 0 📌 0
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The Crick to co-lead the Equality, Diversity and Inclusion in Science and Health (EDIS) group The Crick will co-lead the Equality, Diversity and Inclusion in Science and Health (EDIS) group with hosts, the British Science Association, supported by a £10 million grant over seven years from Well...

We’re excited to be working with @britsciassoc.bsky.social to co-lead EDIS, a coalition working to improve equality, diversity and inclusion in science and health research.

Find out more about the plans for EDIS's next chapter ⤵️ www.crick.ac.uk/news/2026-03...

04.03.2026 13:40 👍 14 🔁 6 💬 0 📌 0
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TriRhena Gene Regulation Club Meeting in March 2026.

📍 Location: @igbmc.bsky.social, Strasbourg 🇫🇷
📅 Date: March 18, 2026 | 2:00 PM

🆓 Participation is free of charge, advance registration is required. Register your abstracts for 20-minute research talk.

www.ie-freiburg.mpg.de/gene-regulat...

23.02.2026 11:30 👍 5 🔁 2 💬 0 📌 1

Final version @nature.com of our paper describing unconventional multicellular development in a choanoflagellate inhabiting an extreme environment. A ton of new data since the first @biorxivpreprint.bsky.social preprint (which we've kept updating).

A brief 🧵 (carried over from the old place)

28.02.2026 08:12 👍 362 🔁 147 💬 16 📌 16

One week left to register to the Bioimage Analysis with AI course in Pasteur!

This June, 1 - 5.

I give a bit more details in the thread below
👇

24.02.2026 19:48 👍 39 🔁 29 💬 1 📌 1
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Interesting review from the Notani lab on the different functions and regulatory architectures of transcriptional hubs- including #actin; doi.org/10.1016/j.gd...

23.02.2026 10:41 👍 0 🔁 0 💬 0 📌 0
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Finding one mutation that improves a protein is hard. Finding five that work together is exponentially harder.

Today in @science.org, Hsu and Konermann labs present MULTI-evolve, a lab-in-the-loop framework that does it in just one machine learning-guided round.

19.02.2026 19:50 👍 55 🔁 20 💬 1 📌 0
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Actin Counters Geometry to Guide Plant Cell Division - preLights When geometry isn’t enough, actin helps plant cells decide where to divide, ensuring robust tissue patterning

When geometry isn’t enough, actin helps plant cells decide where to divide, ensuring robust tissue patterning. 🌱 #PlantBiology

Goldy & team uncover a central role for F-actin as a cortical landmark.

#preLight by Jeny Jose @umeaplantsciencecentre.se ⬇️ 👀
prelights.biologists.com/highlights/a...

27.11.2025 10:42 👍 13 🔁 2 💬 0 📌 0
Research Associate - Godlee Group (Fixed Term) We are seeking to recruit a postdoctoral Research Associate with a background in cell biology and interest in infection research to join the laboratory of Dr Camilla Godlee in the Department of

We have an exciting 3-year postdoc position available to study how Salmonella remodels host membrane dynamics.

If you have a background in cell biology and are interested in working on an infection project this could be for you!

Application deadline - 24th February.

www.cam.ac.uk/jobs/researc...

18.02.2026 11:09 👍 7 🔁 9 💬 0 📌 0
 Cdc42 accumulates in aged cells, and reducing its levels extends life span.Two representative WT cells expressing Cdc42-mCherrySW are shown at selected ages and time points (hr: min) from initial loading. White arrowheads indicate cells during or shortly after cytokinesis, when Cdc42 levels are quantified. Black and red arrowheads denote the same cells at other cell cycle stages and cell death, respectively. Scale bar: 3 µm.

Cdc42 accumulates in aged cells, and reducing its levels extends life span.Two representative WT cells expressing Cdc42-mCherrySW are shown at selected ages and time points (hr: min) from initial loading. White arrowheads indicate cells during or shortly after cytokinesis, when Cdc42 levels are quantified. Black and red arrowheads denote the same cells at other cell cycle stages and cell death, respectively. Scale bar: 3 µm.

Cdc42 is a small GTPase crucial for #CellPolarity, but how does it contribute to #aging when upregulated? This study shows that the ER-anchored chaperone Ydj1 interacts with Cdc42, enhancing its stability & partitioning during asymm #CellDivision & aging in yeast @plosbiology.org 🧪 plos.io/4qz7WaM

16.02.2026 09:05 👍 4 🔁 3 💬 0 📌 1

The bumpy road leads to the nucleus--cool new mechanobiology!

15.02.2026 14:07 👍 13 🔁 3 💬 2 📌 0
LinkedIn This link will take you to a page that’s not on LinkedIn

My lab @cri-utsw.bsky.social is looking for a highly motivated postdoct interested in mechanobiology!

We are building a highly collaborative and interdisciplinary team working on how mechanical forces shape immune and cancer cell behavior.

Come do cool science with me!

lnkd.in/gKEXWUGy

13.02.2026 14:46 👍 9 🔁 10 💬 0 📌 0
University of Freiburg

PhD opening
Join a collaborative, interdisciplinary project the Excellence Cluster Future Forests @uni-freiburg.de, working on CRISPR/Cas in poplar to understand how trees cope with climate stress.
Apply here: uni-freiburg.de/en/job/00004...
@dompsfr.bsky.social @biologyunifreiburg.bsky.social

11.02.2026 09:57 👍 26 🔁 32 💬 0 📌 2
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Happy International Day of Women and Girls in Science! 🧪 Don't forget to send in your nominations for the FEBS | EMBO #WomenInScience Award.

Deadline: 15 May

Read more:
https://www.embo.org/the-embo-communities/febsembo-women-in-science-awardees/nominate-for-the-women-in-science-award/
#award

11.02.2026 08:35 👍 71 🔁 39 💬 0 📌 1
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A high-resolution, easy-to-build light-sheet microscope for subcellular imaging An accessible light-sheet microscope delivers subcellular-resolution, multicolor volumetric, and live-cell imaging, lowering barriers to state-of-the-art performance.

In @elife.bsky.social: A high-resolution, easy-to-build light-sheet microscope for subcellular imaging doi.org/10.7554/eLif...

05.02.2026 22:53 👍 47 🔁 23 💬 1 📌 0
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Structural biologist Alexey Amunts launches new research lab in Shenzhen ‘Shenzhen adds another dimension; it is a place where ideas do not remain ideas for long,’ Amunts says of new position.

We're launching a research lab at SMART. Shenzhen Medical Academy for Research and Translation is a newly established institute with long-term funding mechanisms for internal and external investigators. At full capacity SMART aims to support up to 400 labs.
www.scmp.com/news/china/s...

06.02.2026 05:33 👍 71 🔁 19 💬 2 📌 2
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Apply now! The 2026 call for the EMBO Young Investigator Programme is now open with a deadline of 1 April 12:00 midday CEST. 🧪

More info here:
https://www.embo.org/funding/fellowships-grants-and-career-support/young-investigator-programme/
#LifeSciences #research #funding

02.02.2026 09:15 👍 23 🔁 23 💬 0 📌 2

what a great opportunity!

06.02.2026 08:27 👍 0 🔁 2 💬 0 📌 0
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IMPRS PhD Program The IMPRS-EBM is an international PhD program that lies at the intersection of Epigenetics, Biophysics and Metabolism. It integrates strategies from molecular biology and biochemistry with biophysical...

Open PhD position – join our lab in Freiburg

Through the IMPRS (Max Planck) program, we are looking for a motivated PhD student interested in signalling, and developmental mechanisms.

Be quick - deadline is tomorrow!

www.ie-freiburg.mpg.de/IMPRS-PhD-Pr...

05.02.2026 06:33 👍 20 🔁 33 💬 0 📌 1

That‘s the spirit.

05.02.2026 10:46 👍 10908 🔁 3179 💬 33 📌 0

A permanent position as a research scientist is opened in our team! We look for a plant physiologist with expertise in plant / microorganism interactions to identify plant susceptibility factors to fungal disease. Please forward!

31.01.2026 18:35 👍 23 🔁 35 💬 0 📌 0
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We have two funded postdoctoral positions available. Topics encompass:

-Next gen light-sheet fluorescence microscopy instrumentation

-Structured illumination microscopy and other approaches to extend the resolution limit.

-Nonlinear microscopy combined with adaptive optics / phase conjugation

27.01.2026 22:29 👍 51 🔁 25 💬 3 📌 2
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Full Professor and Chair Laboratory of Biophysics We are looking for a Full Professor in the Biophysics chair group, part of Wageningen University & Research (WUR)

The Laboratory of Biophysics at Wageningen University & Research (NL) is looking for a new chair! Details here: www.wur.nl/en/vacancy/f...

27.01.2026 20:13 👍 10 🔁 17 💬 1 📌 0
Flyer with announcement of the FEBS advanced course in Amsterdam

Flyer with announcement of the FEBS advanced course in Amsterdam

Join us in Amsterdam for a FEBS advanced course on "Functional Imaging of cellular dynamics" from 31st of May - 6th of June 2026
Info: microscopy2026.febsevents.org

27.01.2026 11:06 👍 24 🔁 16 💬 0 📌 0
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#LivingArchitectures
We put cells and cytoskeleton filaments on the architecture of the musée d'Orsay.
www.musee-orsay.fr/fr/agenda/ev...
Scientists of the #CytoMorphoLab adapted their protocols to illustrate the questions that keep them awake at night.
-> Two shows on the 24th and 25th of January.

05.12.2025 16:11 👍 303 🔁 102 💬 19 📌 9

As a someone with a 33 year NIH-funded lab whose grant is supposed to be reviewed this week, shut NIH down if that is what's needed to end ICE terrorism. Innocent lives are more important 🧪

25.01.2026 12:59 👍 774 🔁 199 💬 7 📌 9
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German soccer federation official wants World Cup boycott considered because of Trump A German soccer federation executive committee member says it’s time to consider a World Cup boycott because of the actions of U.S. President Donald Trump.

A German soccer federation executive committee member says it's time to consider a World Cup boycott because of the actions of U.S. President Donald Trump.

23.01.2026 22:00 👍 18942 🔁 4949 💬 1162 📌 1529