Congratulations to Prasanna Satpute-Krishnan (@pskcellbio.bsky.social)
for winning the USU Henry C. Wu Award for Excellence in Basic Science Research!
Congratulations to Prasanna Satpute-Krishnan (@pskcellbio.bsky.social)
for winning the USU Henry C. Wu Award for Excellence in Basic Science Research!
From MBoCβ¦ Cells move cargo in clever ways. John Salogiannis (University of Vermont) reveals how the protein AcbdA helps peroxisomes hitchhike on early endosomesβconnecting intracellular transport with fatty acid metabolism. www.molbiolcell.org/doi/full/10....
The Reck-Peterson lab at Weill Cornell Medicine is seeking a technician or staff scientist to work on Aspergillus projects. Broad background in fungal biology and techniques required. Bioinformatics skills preferred. Find out more at: reckpetersonlab.org.
#CellBio2025
This Wednesday, Dec 10 at 9:00 AM in Room 122
Please add it to your schedule!
The zo computer allows one to try different AI models www.zo.computer (they normally give the same answers but some are better organized) (in setting, choose my AI, then it should allow you to choose)
Give the laurels to the one who earned them.
A thread that aims to attribute credits to the originators of important βfirstsβ
This is on the making. Please contribute to accurate historical records with comments and reading recommendations
π§΅π
Without these possibly impossible mutants, it is hard to falsify that LLPS may play a role somewhere in the process just as more specific protein-protein interactions. Both could be necessary (neither is sufficient). I have never worked on LLPS. These discussions are very helpful! Thanks!
I enjoyed reading the paper! The mutant data is convincing that LLPS canβt be the sole driver of protein localization in cells. It would be even better to obtain mutations that disrupt LLPS and show no effect on cellular localization, but this must be hard given the nature of the interactions.
My postdoctoral mentor N. Ronald Morris passed away on Nov. 20, 2025. He was 92. I am forever grateful to his mentorship and his visionary use of Aspergillus nidulans as a genetic system to explore fundamental questions in cell biology. www.hillsboroughfuneralhome.com/obituaries/D...
I had fun checking out the endomap site (endomap.hms.harvard.edu/network). Surprisingly, PRPF40A (pre-mRNA splicing, Huntingtin-interacting, Aspergillus homolog Prp40A involved in cytoplasmic dynein function) connects to axonemal dynein light intermediate chain polypeptide, which is interesting!
www.dha.mil/News/2025/05...
Very proud of my colleague @pskcellbio.bsky.social and her lab for this important work on the clearance of misfolded GPI-anchor proteins out of the ER (supported by the NIH)!
journals.plos.org/plosbiology/...
Thank you Ferdos!
Preprint from our lab is out! We identified a peroxisome-localized acyl-coA binding protein AcbdA - that regulates peroxisome movement. www.biorxiv.org/content/10.1.... Congratulations to members of my lab and the Christensen lab
@christensenlab.bsky.social www.biorxiv.org/content/10.1...
Beautiful work! Aside from the motor cooperation theme, this paper shows an insightful structure of the FHF complex (initially isolated by Wade Harper lab at Harvard. Xu et al 2008 MBoC). The structure contains FTS, the C-terminal part of Hook3 and FHIP1B. What a journey! Congrats to Abid Ali et al!
Our lab at the NIH (Bethesda, MD) is looking for postdoctoral fellows to join our team studying the molecular mechanisms of protein trafficking and their links to neurodevelopmental disorders starting on or after 10-1-2025. Send your application to juan.bonifacino@nih.gov. Please share and repost!
Thank you so much Prasanna!
Happy to share this short spotlight piece kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F... published online by @cp-trendscellbio.bsky.social
for an interesting paper about an unexpected mechanism behind Kinesin-1-mediated meiotic spindle positioning in C. elegans @cp-cellreports.bsky.social
Wow! Congratulations!
LC8 moonlighting (most likely) in channels. Nice work!
An interesting read. Neil Gow just gave a fantastic talk at the #ecfg17 on fungal cell wall components- on mannose polymers that can either be a flag or a mask for different immune cells. The part on the malaria parasite is also fascinating.
Just learned about this amazing work! doi.org/10.1016/j.cub.2024.12.041
Today in #journalclub, we looked at this fantastic new method from the @doudna-lab.bsky.social in Nature Biotechnology! They show how CRISPRβCsm enables single-molecule live-cell imaging of endogenous RNAs. Super cool!
www.nature.com/articles/s41...
our first serious attempt to understand F-actin (F standing for filamentous, among other things) in Aspergillus nidulans: www.biorxiv.org/content/10.1...
Review in Nature
Case et al.
Fungal impacts on Earthβs ecosystems
www.nature.com/articles/s41...
Interesting! I guess they may still have it to get rid of lactic acid produced in muscle.
I am excited for this opportunity to chair the Department of Biochemistry and Biophysics at Weill Cornell Medicine! news.weill.cornell.edu/news/2025/01...
The deadline to attend the βIntegrating cell and planetary scales to address climate resilienceβ EMBO meeting is Feb 1st! We are bringing together scientists, funders, and policy makers. Join us for this exciting meeting: meetings.embo.org/event/25-cli...
This is such a sad news! I remember talking to him at meetings many years ago and learning about the Rab11-centrosome connectionβ¦
Graphical abstract of the Organelle Profiling paper, showing the workflow: Endogenously tagged organelle library; Native IP proteomics; Data-driven graph clustering; resulting in a subcellular proteome map with more than 7,600 proteins localized across 19 subcellular compartments.
Time to share our organelle proteome paper
out in @cellcellpress.bsky.social: doi.org/nzwz
We created a spatial map of human cells using organelle immunoprecipitation at scale.
Locate your fav protein among the 7,600 we mapped across 19 subcellular compartments: organelles.sf.czbiohub.org/
1/3 π§ͺ
I'm looking to database organelle dyes which work in fungi. Please comment if you can contribute w/ details.
We regularly see @mrccmm.bsky.social that some don't work in some fungi, but I just don't think it's been tested properly #Mycoscopy
I started this w/ Alex Lichius years ago, tip of the π§!