Congrats. Thatโs a great story!
03.03.2026 19:02
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Congrats. Thatโs a great story!
Our preprint is published in MSB! This time with the correct preprint post below! link.springer.com/article/10.1...
The public event "CRISPR Gene scissors in Dresden" is taking place March 26 to 29. The "CRISPR-Roadshow" is teaming up with partners @mpi-cbg.de, @tudresden.bsky.social, and @crtd-tud.bsky.social for a wide range of activities on the CRISPR/Cas method. www.crispr-whisper.de/2025/10/01/d...
Insights from the 2nd EuroDepMap Symposium are now out in FEBS Letters.
Last November at Human Technopole researchers in cancer functional genomics and computational biology discussed challenges and future directions in mapping cancer vulnerabilities and building predictive frameworks.
Link โฌ๏ธ
Our thoughts, impressions, and presentations of the "2nd EuroDepMap symposium" in Milan (Nov 2025) are online at
@febsletters.bsky.social.
febs.onlinelibrary.wiley.com/doi/10.1002/...
You know your crowedโฆโฆ thanks for sharing - will take a deep dive.
๐ซ Thank you to all participants and speakers who joined us at the 2nd @eurocancerdepmap.bsky.social Symposium!
Together, weโre advancing #cancer functional genomics across Europe.
youtu.be/Qt_ozbzM5js
Start of the second session of the 2nd EuroCancerDepMap symposium with a talk from Manuel Kaulich
The Synthetic Lethality and Innovations in CRISPR Screening session begins with @manuelkaulich.bsky.social telling us about exciting CRISPR libraries they have developed and how nuclear mRNA processing can mask the CRISPRko phenotypes @eurocancerdepmap.bsky.social
Beeswarm plot of the prediction error across different methods of double perturbations showing that all methods (scGPT, scFoundation, UCE, scBERT, Geneformer, GEARS, and CPA) perform worse than the additive baseline.
Line plot of the true positive rate against the false discovery proportion showing that none of the methods is better at finding non additive interactions than simply predicting no change.
Our paper benchmarking foundation models for perturbation effect prediction is finally published ๐๐ฅณ๐
www.nature.com/articles/s41...
We show that none of the available* models outperform simple linear baselines. Since the original preprint, we added more methods, metrics, and prettier figures!
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In times when science must defend itself, the decision by the German Research Foundation (DFG) to significantly support German universities through the Excellence Initiative for the next seven years is a signal that stands unparalleled.
www.dfg.de/en/news/news...
Such a wonderful example of what genetic screens can tell us about human patho/physiology.
Cudos @mgarnett.bsky.social, Fiona Behan and many more.
Congratulations! & thanks for letting us contribute to this wonderful story.
Congratulations. On top of my reading list.
A record lowโฆ. only 16% of Germans think that Germany can trust the US.
A record fastโฆ. never before lost a US president support for its political agenda that fast.
www.spiegel.de/politik/deut...
If a team wished to include combinatorial gene perturbation and bioinformatics in their program, please reach out.
New Gordon Research Conference Alert: Synthetic Lethality Approaches in Oncology. www.grc.org/synthetic-le....
Join us 20-25th July 2025 for an intimate meeting with thought leaders in the field. Great for networking and opportunities for early career scientists to present their research.
80% of Germans (84% participation) voted for democracy.
#TogetherAgainstPopulism
Interested in synthetic lethality or how functional genomics can be leveraged for clinical benefit?
Then, this is the place to meet:
www.grc.org/synthetic-le...
If you search for unexpected phenotypes (genetic interactions), aren't they expected when observed? ๐ค
Which rate do you consider appropriate,
10% or 1% ?
Thinking about grant alternatives to fund basic research?
Provocative thought - How about getting a royalty rate per accessed publication (per corresponding author)?
๐ฃRegistration is now open for an exciting Gordon Conference on synthetic lethality organized by Ben Schwartz (GSK), Mathew Garnett (Sanger), and Francisca Vazquez (DepMap Director, Broad Institute)
Highly recommended!
Register here
grc.org/synthetic-le...
Hi Vanessa, I can contribute to Cancer Biology, Functional genomics, and Bioinformatics.
Please add me to the pack.
FYI ๐The abstract deadline for #cshlnetworks is coming up - Jan. 27th! Register to submit your abstract here:
bit.ly/40cIfSl
@fritzroth.bsky.social @jsvanleeuwen.bsky.social @pedrobeltrao.bsky.social
The German Research Council, aka DFG, is on BlueSky.
Welcome @dfgpublic.bsky.social
Bursary deadline: 14 January 2025 Abstract deadline: 4 February 2025 In-person registration deadline: 4 March 2025 Virtual registration deadline: 25 March 2025
Make your mark on the future of #PrecisionMedicine
at #CRISPR25!
Showcase #CRISPR methods for modulating the genome at scale๐งฌ
๐ฆ๐๐ฏ๐บ๐ถ๐ ๐ฎ๐ป ๐ฎ๐ฏ๐๐๐ฟ๐ฎ๐ฐ๐ ๐ฏ๐ ๐ฐ ๐๐ฒ๐ฏ๐ฟ๐๐ฎ๐ฟ๐ for a chance to build your professional profile at the forefront of a global community.
๐ bit.ly/3BDXOtP
Are you interested in how genes/proteins interact to regulate cellular and organismal physiology?
If so, let's grab a coffee at the upcoming #CSHL Network Biology meeting.
meetings.cshl.edu/meetings.asp...
I messed up my earlier message by using the wrong link/date. So here is the correction!!
See you in Hinxton (2โ4 April, 2025)
coursesandconferences.wellcomeconnectingscience.org/event/crispr...
Thanks for sharing this @durocher1.bsky.social
Any chance you have a link to behind the paywall? Thx.