Alessio Ugolini

Functional reprogramming of neutrophils within the brain tumor microenvironment by hypoxia-driven histone lactylation Abstract. Despite functional heterogeneity, high frequency of intratumoral neutrophils predicts poor clinical outcomes. The tumor microenvironment reprograms neutrophils into immunosuppressive subsets...

I am thrilled to share that our latest work has been published on Cancer Discovery.
In this manuscript, we provided a potential therapeutic strategy to counteract neutrophils-induced immunosuppression in cancer.
doi.org/10.1158/2159...