Each gene in CENTRA comes with its own radar plot visualizing key topological properties:
π‘ Centrality
πΏ Local fractality
π‘οΈ Robustness
Perfect for comparing genes across different biomedical topics.
@sinzandrea
Full (W3) Professor Pharm. Chem. & Bioanalytics at MLU Halle-Wittenberg; Center for Structural Mass Spectrometry https://agsinz.pharmazie.uni-halle.de https://rtg2467.uni-halle.de/ #teammassspec #massspec #ChemSky Structural proteomics, cross-linking MS
Each gene in CENTRA comes with its own radar plot visualizing key topological properties:
π‘ Centrality
πΏ Local fractality
π‘οΈ Robustness
Perfect for comparing genes across different biomedical topics.
Love this picture!ππ
Helgas AlmhΓΌtte???
Great cooperation I am really proud of!π§ͺπ
Great talks on the first day of our retreat! It is fantastic to see the progress that has been made in the projects during the last year!π§ͺ
To be honest, when I see conferences announced that have a majority of male invited speakers, I think the organisers are not trying hard enough. We have so many excellent #FemalesinMS and resources available there is really no excuse for it anymore #massspec #teammassspec #lipidomics #metabolomics
βΆοΈ I am now mainly active on LinkedIn. Looking forward to meeting you there @linkedin.com! π§ͺπ§¬π¦
Life-changing eye implant helps blind patients read again.
π§ͺποΈ
www.bbc.com/news/article...
The world joined us and said, βNo Kings.β
Poster Image with a woman yelling into a megaphone.; Title reads: Fight for Science. Bubbles read: 3:00pm, Rally, Oct 17th.; Subtitle reads: Health and Science for the People!; A pin emoji with text: 200 Independence Ave SW, Washington DC; a Virtual Call emoji with text: Join us virtually at: bit.ly/4mXwrfY ; bottom corner has QR code and a logo for Stand Up For Science
FIGHT FOR SCIENCE RALLY βπ
β° WHEN: October 17th, 2025
πWHERE: 200 Independence Ave SW, Washington DC!
RSVP to JOIN THE FIGHT IRL: zurl.co/LayiM βΌοΈ
π² Join us Virtually!: zurl.co/Um47l
π§ͺWhat a fantastic symposium with such amazing science! Thank you π Andrea Graziadei, @claudio-iacobucci.bsky.social and Lolita Piersimoni, for getting this organized!πππ
@humantechnopole.bsky.social
Next year this symposium will be held in San Franciscoβ¦
#teammassspec #academicsky #chemsky
π§ͺ Michal Sharon just gave a fantastic talk @ssp2025.bsky.social on how native MS can give detailed structural insights into the circulating 20S proteasome. π @humantechnopole.bsky.social #teammassspec #academicsky
π§ͺ Paola Picottigives a great keynote lecture on decoding the protein dance. What a fantastic first day of the @ssp2025.bsky.social at @humantechnopole.bsky.social in Milan!π
π§ͺ
www.nature.com/articles/s41...
π§ͺ And this is the second Nature Communications @natcomms.nature.com paper where we contributed:
www.nature.com/articles/s41...
@academic-chatter.bsky.social @academicsky.org #teammassspec
@unileipzig.bsky.social @unihalle.bsky.social
Figure 3 from the paper with the caption: "Role of machine learning in de novo design of IDRs. (A) Machine-learning models can be trained on diverse data sources, from molecular dynamics simulations to annotations of cellular localization and protein structures from the Protein Data Bank. (B) Often implemented as neural networks using sequence-encoded features as input, these models can initially be trained on a limited region of sequence space as surrogate models. Through active learning, additional simulations are performed during the design campaign to generate new data, and the surrogate model is retrained on the expanded dataset to progressively improve its accuracy. (C) Machine-learning models have been developed to predict biophysical observables, biological annotations, and protein structures. When combined, machine-learning models can be used to identify a set of sequences that strike a trade-off between multiple design objectives, defining a Pareto front."
New review on computational design of intrinsically disordered proteins π₯οΈπ by @giuliotesei.bsky.social @fpesce.bsky.social & π΄
doi.org/10.48550/arX...
π§ͺThis works impressively demonstrates the power of integrated approaches to gain important structural insights into GPCRs. XL-MS, biochemical assays, and MD simulations were combined in this study.
#pharmsky #chemsky #GPCR
βΌοΈ Our Nature Comm paper is finally online!π
pubmed.ncbi.nlm.nih.gov/40973726/
I am so proud of this joint work with Anette Kaiser @unileipzig.bsky.social. We investigate the interactions of the Y2 receptor with NPY. Thank you all who contributed! π πͺ
@unihalle.bsky.social #chemsky #academicsky
After years of complaining about cancel culture, the current administration has taken it to a new and dangerous level by routinely threatening regulatory action against media companies unless they muzzle or fire reporters and commentators it doesnβt like.
I absolutely love the Sagrada Familia; it is breathtaking. π₯°
#PhD
Actually, Alessio has two twins! Look at the picture: one is a real twin, the other one is notβ¦can you tell who is who???πππ
Jacopo, Alessio, and Andrea.
Alessio with his hat after the defense.
Alessio Di Ianni from our group just defended his thesis on studying intrinsically disordered proteins by XL-MS. Bravo!ππ Fantastic defense and discussion! π #proudPI @unihalle.bsky.social @humantechnopole.bsky.social #RTG2467 #Academicsky #pharmsky #chemsky
This publication also counts for our SFB1664! π@snp2prot.bsky.social @unihalle.bsky.social @ipbhalle.bsky.social
π
Third Nature Comm paper accepted within two weeksβ¦I have never had this beforeβ¦π
Suche dir so frΓΌh wie mΓΆglich gute und erfahrene Mentor*innen! Netzwerke von Frauen in der Wissenschaft sind extrem wichtig. @femalesinms.bsky.social
Our manuscript "Conserved hydrophilic checkpoints tune FocA-mediated formate:H+ symport" has just been accepted at Nature Communications!ππ I feel truly honored to be part of this work that was headed by Panos Kastritis and Gary Sawers.More information to follow! @unihalle.bsky.social
#Academicsky
Green Chair Blue Chair
by me
#photography #streetphotography