New preprint! The same TFs can drive distinct regulatory programs depending on where they bind.
TSS → rapid stress responses
Intronic & upstream → cell-type programs
Enhancer-like CRMs → embryo/meristem programs
Coding-sequence binding → repression
www.biorxiv.org/content/10.6...
This is a very special paper for me. I had the idea of combining transcription factor binding with chromatin in 2016/8. It took some time, but thanks to Fred and Vikas, we can finally share the story in @plos.org Genetics looking at chromatin states in Arabidopsis and Marchantia. #PlantScience
Absolutely delighted that our paper on epigenetic dynamics during plant aging is out today in Science!
www.science.org/doi/10.1126/...
Given the described activators of cambium growth, we reasoned repressors were needed to balance the system. Here they are! www.biorxiv.org/content/10.6...
Discovery: Xing, Jingyi, Emma, Riikka, Anne-Maarit, Julia, Qing, Hanan, Raluca, Joanna, Yuqi, Wiki
#plantscience #plantdev
Our paper is out in MBE! doi.org/10.1093/molb...
We tracked TF binding site evolution across 589 grass species, and found that while binding preferences are pretty stable over 80 million years of evolution, individual binding sites have turned over a lot.
Thread here: bsky.app/profile/char...
Targeting T-DNA to a specific locus using CRISPR
From: onlinelibrary.wiley.com/doi/full/10....
GLPSC 2025 attendees pose together on the sidewalk in front of the Grand River for a group photo
Thank you to everyone who attended the 1st Great Lakes Plant Science Conference and helped make it a success! This inaugural meeting brought together 416 registrants from 55 institutions. Together, we’ve built momentum for the future of #plantscience in the Great Lakes region and beyond! #GLPSC2025
MSU is great place to do plant science research. My lab will be a great place to develop new expertise in genomics and plant molecular biology.
Application instruction and link: careers.msu.edu/jobs/researc...
Please email me if you have any questions.
Please share! I'm looking for a postdoc. The position is to lead one of the following projects: 1) regulation of plant specialized metabolism by cell fate, or 2) foliar embryogenesis in the succulent plant Kalanchoe.
Learn more abt projects: cxli233.github.io/cxLi_lab/res...
Our #research on #drought #recovery, now published with @springernature.com in @natcomms.nature.com:
Drought recovery in plants triggers a cell-state-specific immune activation.
doi.org/10.1038/s414...
Read thread below 👇
delighted to share work from my postdoc @cshlnews.bsky.social - here, we use TurboID in maize meristems to be able to resolve CLV receptor interactions, unlocking its potential to resolve in vivo receptor interactions important for meristem signaling.
Single-cell-level response to drought in Sorghum bicolor reveals novel targets for improving water use efficiency https://www.biorxiv.org/content/10.1101/2025.08.28.671794v1
TL;DR: Great perspective by Mary Galli & Andre Gallavotti 👉https://bit.ly/3Jz59yF
Very grateful to have worked with an exceptional team: @leobaumgart.bsky.social, @greensi.bsky.social, @abmora.bsky.social, Peng Wang, and Yu Zhang
Our new Nature Plants paper is out (and we’re on the cover 😁)!👉 bit.ly/4lS8sOB
By combining scRNA-seq with conserved TF binding (multiDAP) we define gene regulatory networks for 65 cell types across 4 tissues in a wide range of flowering plants!
A great example of how comparative genomics across the full range of vascular plant lineages can be used as a catalyst for gene discovery!
Exciting new single cell datasets for gymnosperms, ferns and lycophytes!
The scale of this study is really amazing!
www.cell.com/cell/fulltex...
The August issue is now fully online, with a beautiful cover that might be a nostalgia trigger for some of us (young people can find an explanation in the Editorial):
www.nature.com/nplants/volu...
This project was a huge team effort with five(!) co-first authors, including JGI scientists @leobaumgart.bsky.social, @abmora.bsky.social, Peng Wang, and Yu Zhang each playing crucial roles, and @omalley-regulome.bsky.social at the helm.
An amazing group!
