If you have anything to do with young people(I’m a a High School Trustee, my wife is a Girl Guide Commissioner) the scars are still clear, if you take even a moment to look.
06.03.2026 13:28
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If you have anything to do with young people(I’m a a High School Trustee, my wife is a Girl Guide Commissioner) the scars are still clear, if you take even a moment to look.
This:
1 We know that “data” is plural but we were in a hurry.
Something incredible I learned (re-learned?) tonight is that the blog post where the first SARS-CoV-2 genome was shared - six years ago on Saturday - included the most iconic footnote of all time
Save the date! Next year's European #RDKit UGM will take place from 16-18 September in Darmstadt, Germany.
Pre-registration will open in early 2026.
A screenshot showing that my "rdkit_new" conda environment is running the 2025.09.1 RDKit release
Yay! #RDKit
Great news! 🎉
Following an independent expert review, we have formally nominated the broad-spectrum pan-coronavirus antiviral ASAP-0017445 as a pre-clinical drug candidate.
🔗Read the press release here: dndi.org/press-releas...
I first wrote about some of the early stages of this project in March 2020 (cen.acs.org/pharmaceutic...).
I've been privileged to follow along since then (cen.acs.org/pharmaceutic...).
Congratulations to everyone who contributed.
It’s the travel choice of the future…
And Milan Centrale is an architectural wonder!
Thanks to @greglandrum.bsky.social and all the #RDKit crew another great UGM,now back along the Elbe as the sun sets:
Members of Dr. White’s lab, from left to right, wearing white lab coats: Briana McGovern, BS, Senior Research Associate; Meg Gordon, BA, Research Associate; Dr. White; Dr. Suazo; Jared Benjamin, MS, Research Associate.
ASAP is incredibly proud to work with superstar antiviral discovery scientists at Mount Sinai: Briana McGovern, Meg Gordon, Dr. Kris White, Dr. Suazo, and Jared Benjamin, among others!
Read about their important work here:
health.mountsinai.org/blog/stories...
Down the Elbe to Prague, great way to get to #RDKit:
Picture shows the side of a European Sleeper carriage in maroon livery with “Euro-Express” text on the side.
Sleeper Brussels to Prague, quite traditional for a game changer.
Avanti West coast train, yellow and turquoise livery arriving at Macclesfield (UK) station under the bridge with the word Macclesfield written across it under a blue sky with thin white clouds.
Heading overland to the #RDKit UGM, trying out the sleeper Brussels ->Prague from a London-> Brussels Eurostar. But first:
Disease prevalence in US states before & after vaccine introduction 🧪
From Edward Tufte & graphics.wsj.com/infectious-d...
Results so stunningly clear they inspired this classic xkcd (xkcd.com/2400/):
Ouch…
AI advances are all about getting enough good data. For the first time this is data at the scale we need it for faster drug discovery. This could make a difference to so many diseases.
If you weren’t able to attend our Symposium on Open Drug Discovery in Montreal in April, you’re in luck - the recordings are now on YouTube and the slides are on Zenodo!
🎥 Watch the recordings: www.youtube.com/playlist?lis...
📄 Access the slides: zenodo.org/communities/...
Learning about European approaches to Pandemic Preparedness “We’re not safe till we’re all safe”:
@asapdiscovery.bsky.social
at: health.ec.europa.eu/events/hera-... #HealthUnion
Brilliant explainer from Pascale how to use patents as enablers in preparing for the next pandemic.
Today, @griffen-ed.bsky.social explains at the Open Drug Discovery Symposium how @asapdiscovery.bsky.social has developed a hybrid intellectual property model that counterintuitively uses patents to support open science innovation and ensure affordability & global access.
🔗 shorturl.at/gMY0t
and I'm talking about it at the Conscience symposium next week in Montreal: conscience.ca/symposium2025
If this sparks your interest there's more of our background thinking published on open access in Wellcome Open Science: wellcomeopenresearch.org/articles/9-374
Here’s a post on this molecule, and good luck to all involved!
Massive credit to all members of @asapdiscovery.bsky.social :- drug discovery is a massive team sport. Especially the chemists at Enamine working through the war.
If you, like me, do not particularly want to die by bleeding out of your eye sockets from diseases like Ebola, and think it's dumb to cut funding for viral countermeasures for future pandemics "because the COVID pandemic is over", here's something you can do about it:
resist.bot/petitions/PX...
New pancoronavirus antiviral targets the main protease (Mpro) of the two different coronaviruses that cause Middle East respiratory syndrome (MERS) and COVID-19. Via @laurahowes.bsky.social @cenmag.bsky.social cen.acs.org/acs-news/acs...
