Gracias por tu valentía y por ayudar a dar visibilidad a la situación que viven miles personas con #VIH, realidad sobre la que hemos puesto el foco en nuestro 30 aniversario. Cuentas con el apoyo y la atención de quienes nos dedicamos a tratar el virus.
🫂 Los socios y socias de GeSIDA estamos con Eduardo Casanova. Por su valentía a la hora de manifestar su estado serológico y ayudar a derribar el estigma que soportan muchas personas.
Y también, porque estamos a su disposición para cuidar su salud y a disfrutar de la mayor calidad de vida.
#MeToo
Clinical Practice Guideline by Infectious Diseases Society of America (IDSA): 2025 Guideline on Management and Treatment of Complicated Urinary Tract Infections: Timing of Intravenous to Oral Antibiotics Transition for Complicated UTI url: academic.oup.com/cid/article/...
Revisión de Infecciones recurrentes por Clostridioides difficile
Recurrent Clostridioides difficile Infections url: jamanetwork.com/journals/jam...
In this era of precision medicine, IDSA instead recommends individualized, dynamic decision-making that takes into account each patient´s evolving trajectory, severity of illness and balance of clinical features for and against coinfection.
Most patients do not have bacterial coinfections, and briefly withholding antibiotics for patients with nonsevere illness to clarify the diagnosis is safe.
It is noted in the guidelines that bacterial coinfections are common and that delaying antibiotics may be harmful. IDSA notes, however, that nondiscriminatory use of antibiotics for patients with CAP and positive viral assays confers more risks than benefits.
Declined to endorse the guidelines because they include recommendations for use of antibiotics in outpatients with comorbidities and inpatients with nonsevere CAP who test positive for respiratory viruses.
La IDSA no respalda 2 de las 10 recomendaciones
Infectious Diseases Society of America (IDSA) Position Statement: Why IDSA Did Not Endorse the Community-Acquired Pneumonia Guidelines 2025 Update url: academic.oup.com/cid/article-...
From TRIO to one: simplification to bictegravir/emtricitabine/tenofovir alafenamide in highly treatment-experienced people living with MDR HIV url: academic.oup.com/jac/article-...
Post-exposure prophylaxis with doxycycline (DoxyPEP) to prevent STIs in a real-world setting: the PRIDOX study url: academic.oup.com/jac/article/...
A bracketed breakpoint indicates that the agent is simply not efficacious without the use of additional therapeutic measures, but does not address the risk of rapid drug resistance development.
When selecting antimicrobial therapy, that just because breakpoints for an agent are not in brackets, monotherapy may not be suitable.
Un punto de corte entre paréntesis indica que el agente simplemente no es eficaz sin el uso de medidas terapéuticas adicionales, pero no aborda el riesgo de desarrollo rápido de resistencia a los fármacos.
A tener en cuenta, al seleccionar una terapia antimicrobiana, el hecho de que los puntos de corte de un agente no estén entre paréntesis implica que la monoterapia puede no ser adecuada.
Rifampicin as monotherapy for infections caused by Staphylococcus aureus: considerations for not applying ‘breakpoints in brackets’ url: academic.oup.com/jac/article/...
Actualización de 2025 de las Directrices Wiki para el tratamiento de la osteomielitis piógena en adultos - The American Journal of Medicine www.amjmed.com/article/S000...
Prophylactic Antibiotics for Upper Gastrointestinal Bleeding in Patients With Cirrhosis url: jamanetwork.com/journals/jam...
Editorial que acompaña el artículo
Thanks to @absteward.bsky.social for finding the most recent Shorter is Better: TB Is Complex Study. Shows 8 week regimens are inferior to 24 week for cure. Sets a lower boundary for TB. Slides and website updated.
www.bradspellberg.com/shorter-is-b...
Shorter antibiotic prophylaxis durations (including 0 days) were noninferior to longer durations for all-cause mortality, but not for early rebleed or bacterial infections.
Prophylactic Antibiotics for Upper Gastrointestinal Bleeding in Patients With Cirrhosis url: jamanetwork.com/journals/jam...
2025 Update to WikiGuidelines for the Management of Pyogenic Osteomyelitis in Adults - The American Journal of Medicine www.amjmed.com/article/S000...
El momento óptimo de administración, las estrategias de dosificación y la selección de pacientes requieren mayor investigación.
Los esteroides sistémicos pueden reducir la incidencia de shock secundario en la neumonía grave. En ambas afecciones, los corticosteroides pueden tener poco o ningún efecto sobre las infecciones nosocomiales.
