Francesco Limone

Thanks @gliameeting.bsky.social for selecting me. It was a very exciting meeting!

We look forward to seeing you Tomorrow Nov 26 at 2PM for the 2nd IGN SYMPOSIUM. A time for Glia related Science, with open and live discussion with the Italian glia community. See you Tomorrow!!! 
unipd.zoom.us/j/83647074227?…

Italianglianetwork.com

Hi gang! I am giving a short talk at the second @italianglianetwork.bsky.social Symposium on Wednesday EU-afternoon/US-morning. Sign up to tune in!

Defining the molecular identity and morphology of glia limitans superficialis astrocytes in vertebrates, Cell Reports

"Defining the molecular identity and morphology of glia limitans superficialis astrocytes in vertebrates"
http://dlvr.it/TPKJSH

@liddelowsa.bsky.social @philiphasel.bsky.social & colleagues
@cp-cellreports.bsky.social
#SfN2025

Good work takes time sometimes and @brianjjoseph.bsky.social runs long marathons! Glad to be part of such an interesting study, great team work 💪🏼

Selective RNA sequestration in biomolecular condensates directs cell fate transitions - Nature Biotechnology Stem cell differentiation is controlled by manipulating RNA condensates.

1/ Excited to share our new study with @brumbaugh-lab.bsky.social, out in @natbiotech.nature.com! P-bodies selectively sequester RNAs encoding cell fate regulators, often from the preceding developmental stage. Releasing these RNAs can drive changes in cell identity. 🧵 www.nature.com/articles/s41...

I am proud to share our work on X-linked Dystonia-Parkinsonism — a rare neurodegenerative movement disorder driven by a SINE-VNTR-Alu retrotransposon insertion in the TAF1 gene.

Read our two companion papers:
🔹 www.biorxiv.org/content/10.1...
🔹 www.biorxiv.org/content/10.1...

🧵 Highlights below!

Proud to present our new paper in @natmetabolism.nature.com

The Neurolipid Atlas: a lipidomics resource for neurodegenerative diseases
lnkd.in/eVzFrmUY

Check out our open-access platform chock-full with iPSC- and 🧠 lipidomics data (www.neurolipidatlas.com).

Now on bioRxiv! Astrocytes in one brain region (cyan) communicate in expansive networks (magenta). Through tool development, tissue clearing, and many hours on our @zeiss-microscopy.bsky.social Z1, we now know these networks are repeatable across mice, plastic, and specific.
doi.org/10.1101/2025...

Calling all Neuroscience postdocs! 🧠 Share your research through SPiNES (Seminars from Postdocs in Neuroscience: Extramural Series) from the NYUGSoM Department of Neuroscience. Applications close 08/20/25. Apply today! 👉 nyumc.qualtrics.com/jfe/form/SV_...
#Neuroscience #Postdoc #ResearchOpportunity

The New York Academy of Sciences and the Leon Levy Foundation Announce the 2025 Leon Levy Scholars in Neuroscience - NYAS The New York Academy of Sciences and the Leon Levy Foundation have announced the 2025 class of Leon Levy Scholars in Neuroscience.

✨😀Congratulations to postdocs Eyal Rozenfeld and Francesco Limone on being named 2025 Leon Levy Scholars by The New York Academy of Sciences!

@sciencelemon92.bsky.social
@eyalrozenfeld.bsky.social
@moccalin.bsky.social
@liddelowsa.bsky.social

www.nyas.org/press-releas...

And the full paper is here - www.pnas.org/doi/abs/10.1....

Thanks to Dave and Joseph for the nice coverage!

The Coming Out of a Transgender Scientist "I know that I am making the right decision because whenever I think about changing my gender role, I am flooded with feelings of relief."

We're disappointed to see Ben Barres's powerful book "The Autobiography of a Transgender Scientist" among the ~400 titles removed from the Naval Academy Library. Needless to say, we're proud to have published his book and will keep it — and his memory — alive.

As an international scholar, I’m learning to speak up—accent and all “My ideas matter more than how I sound,” this postdoc writes

"I stopped seeing my accent as a problem and started to embrace it."

This week's #ScienceWorkingLife: scim.ag/3VpsO7u

@amyxguo.bsky.social from New York, @liddelowsa.bsky.social lab, has characterized the LCN2 tdTomato mice that label reactive #astrocytes & reactive #endothelial cells. First timer at the #GRCGlia2025, she's done great asking good questions. Definitely one to follow 🔬🧬🍅✨ med.nyu.edu/faculty/shan...

Varicose-projection astrocytes: a reactive phenotype associated with neuropathology Glial cells are fundamental for the pathophysiology of all neurological disorders. Astrocytes, the primary homeostatic cells of the central nervous system (CNS), exhibit species-specific characteristi...

🚨The first #preprint of the #FalconeLab is OUT!🥹🚨

We found that varicose-projection astrocytes are not a physiological type of #astrocytes but they are rather associated with neuropathology.

Read more here, feedback is welcome!!

More details👇👇
1/
www.biorxiv.org/content/10.1...

Check out my postdoc work at Ariel Levine’s lab, hot and fresh, describing how you build a dorsal horn!

www.biorxiv.org/content/10.1...

Fresh off the press! We found that degeneration in one retina causes astrocytes to respond retinotopically across *both* hemispheres of the brain. Perhaps astrocytes across the CNS are able to coordinate their responses more than we anticipated... www.pnas.org/doi/10.1073/...

I’m happy to share a free new resource to explore published single cell transcriptomic datasets from the Sanofi Rare and Neurologic Diseases Therapeutic Area.

talk2data.bioturing.com/sanofibrowser

Defining the molecular identity and morphology of glia limitans superficialis astrocytes in vertebrates Hasel et al. show that molecularly and morphologically specialized astrocytes make up the brain and spinal cord surface, thereby creating the glia limitans superficialis. These astrocytes selectively ...

Our paper on the superficial glia limitans is now published - huge thank you to all co-authors that helped getting this work across the finish line! www.cell.com/cell-reports...

Welcome to the Bluesky account for Stand Up for Science 2025!

Keep an eye on this space for updates, event information, and ways to get involved. We can't wait to see everyone #standupforscience2025 on March 7th, both in DC and locations nationwide!

#scienceforall #sciencenotsilence

Super stoked to announce 📣
The *Mosberger lab* is officially open and hiring! We're looking for Research Associates and Postdocs interested in uncovering how the brain makes us move 🧠👋🏻
Learn more and find out how to apply here: mosbergerlab.com

Biomolecular condensates in immune cell fate - Nature Reviews Immunology Recent studies suggest that biomolecular condensates — membrane-less assemblies of proteins and nucleic acids — are involved in regulating gene expression to ensure proper immune cell development. Thi...

1/ Pleased to share our review, published today
@natrevimmunol.bsky.social, highlighting how biomolecular condensates enhance the precision and flexibility of gene regulatory networks that guide fate decisions during normal and pathological immune cell development. www.nature.com/articles/s41...

Modelling human brain development and disease with organoids Nature Reviews Molecular Cell Biology - This Roadmap article discusses recent advances in the production and use of brain organoids to understand brain development and associated disorders. The...

So excited to share our new @natureportfolio.bsky.social review on modeling human brain development using organoids! 🧠 Loved collaborating with the brilliant @lancasterlab.bsky.social , led by the incredible @marcellabirtele.bsky.social Check it out! 🔬 #Neuroscience #BrainOrganoids rdcu.be/d3llp

Lipids: Emerging Players of Microglial Biology Lipids are crucial in mediating microglial metabolism and function. The microglial lipidome is vast and complex, with over 10,000 lipid species. We discuss key lipid classes and their roles in m...

Happy to share our review on how different lipids shape microglial biology in #GLIA journal. 💫 onlinelibrary.wiley.com/doi/full/10....

👉🏽with Gaurav Chopra, Caitlin Randolph, and @katherinewalker.bsky.social

Great to see our paper online!

Amazing collaboration with Neal over the years, with lots of help from others in the Pasca group.

Spatially restricted immune and microbiota-driven adaptation of the gut - Nature Intestinal regionalization is characterized by robust and resilient structural cell states and the intestine can adapt to environmental stress in a spatially controlled manner through crosstalk betwee...

1/ Keen to share the story of my postdoc research out in @natureportfolio.bsky.social! We built a massive resource characterizing the spatial landscape of the gut—and yes, we dug deep into the biology too. If you’ve got a minute, let me walk you through the story. 🧵👇
www.nature.com/articles/s41...

🙋🏼‍♂️

#TBT to grad school alert! Happy to share our paper "Myeloid and lymphoid expression of C9orf72 regulates IL-17A signaling in mice" science.org/doi/10.1126/... Thanks to the very many amazing scientists involved!

@stanleycenter.bsky.social