🦋✂️🧬 🧪 New preprint! Led by @donyaniyaz.bsky.social CRISPR‑Cas9 knockouts of ABCG transporters across butterflies & moths reveal how pigment pathways shape color during development. #CRISPR #Lepidoptera #pigmentation
Feedback welcome 👩🔬
www.biorxiv.org/content/10.6...
Minos transgenesis enables robust, stable germline integration of transgenes in Lepidoptera; providing a reliable alternative to piggyBac, whose native transposases can cause transgene remobilization or instability in moths and butterflies:
Check out our deep dive into the molecular genetics of male-specific cell type : the gorgeous UV-iridescent scales of Sulphur Butterflies
by lab wizards 🦋🔬 🖥️ 🧬
Ling Sheng Loh
@hanliconius.bsky.social
and a big team
1/n
Preprint! Minos-mediated transgenesis in the pantry moth
www.biorxiv.org/content/10.1...
By @donyaniyaz.bsky.social
The Lepidoptera Genomics meeting July6-12 in Crete is going to be amazing and they extended the abstract deadline.
I wish I could go (most of the team is going)
events.gwdg.de/event/880/
Awesome new paper by @lucalivraghi.bsky.social et al.
doi.org/10.1016/j.cu...
in @currentbiology.bsky.social
on the evo-devo of a butterfly color variation
enjoy the show!
Scientific research is a driving force behind human progress. It fuels medical breakthroughs, spurs technological innovations and drives economic growth. Federal funding of research by the National Institutes of Health (NIH) and the National Science Foundation (NSF) is absolutely critical for ensuring that the U.S. maintains its global leadership in science and technology. The unprecedented freeze on the review and issuance of federal research grants is already negatively impacting research and could have significant ripple effects. Ongoing studies may lose momentum if grant renewals or supplement requests are delayed, slowing scientific progress on research the NIH has already invested in. Researchers affiliated with the Society for Developmental Biology carry out critical research on birth defects, which kill twice as many children as cancer does. Slowed progress will delay the development of new therapies and diagnostics, and thus have real public health implications. In 2019, the total estimated cost of birth defect–associated hospitalizations was $22.2 billion. Scientific research is also critical to the U.S. economy more broadly. In 2023 alone NIH funded research not only directly supported 412 thousand jobs, but its overall economic impact rippled out to all sectors of the economy driving more than $92.89 billion in economic activity across all 50 U.S. states and the District of Columbia. It is estimated that every dollar of NIH funding generates $2.46 dollars of economic activity. Finally, federal research funding not only drives impactful research discoveries but also supports the training of the scientists, engineers, and innovators of the future. University laboratories, funded by federal grants, serve as essential training grounds for the next generation of researchers even as they push the boundaries of knowledge. This training prepares young scientists for leadership roles in both academia and industry, helping to ensure that the scientific workforce r…
The Society for Developmental Biology has released a statement on the Unprecedented Disruptions to Biomedical Research in the United States.
