Kajal Mondal

🎉Proud to present our latest paper, out now in Nature Communications: www.nature.com/articles/s41...

RNA Binding Proteins (RBPs) are often full of intrinsically disordered regions (IDRs), but what these regions do during RNA recognition is often unclear. 1/10
#RNA #IDR #RBP

To kickstart this new Bluesky account: We're hiring!
The Bertolin Lab @dundee.ac.uk is looking for a postdoc to work on DNA-end homeostasis & genome stability, funded by Wellcome Trust Award. Exciting science, fantastic environment, founding role in the lab.
Details in the flyer — get in touch! 👇

Research Fellow (Cell Biology/Biophysics/Bioengineering/Biochemistry) The Institute for Digital Molecular Analytics and Science (IDMxS), officially launched on 1 December 2022, is a Research Centre of Excellence (RCE) supported by a total investment of around S$160 mill...

We’re hiring!
Looking for a highly motivated Postdoc to join my lab at NTU Singapore.
Interested in decoding the crosstalk between membrane-less and membrane-bound compartments? DM me directly with a brief letter stating how your background fits the role! ntu.wd3.myworkdayjobs.com/Careers/job/...

Papers are like buses... You wait for ages, then two come along at once.

Huge congrats to @bornanovak.bsky.social and @jefflotthammer.bsky.social for pushing and driving every aspect of this work, preprinted ~1 year ago to the day (Friday before BPS), now published!

www.nature.com/articles/s41...

Decoding RNA–protein interactions using high-throughput methods RNA-binding proteins (RBPs) constitute a diverse class of proteins essential for every stage of the gene expression process. Many RBPs are also linked to human diseases and pathologies. Understandi...

Happy to share the first review article from our lab!

We discuss the landscape of available high-throughput approaches for profiling RNA–protein interactions in vitro and in vivo.

We hope it will be useful when designing your next experiment.

www.tandfonline.com/doi/full/10....

#RNAsky

Pleased to share the final version of this behemoth of a paper, now finally published. I guess I can retire now?
www.nature.com/articles/s41...

More functional data, many thousands of words removed, and a few other updates from last year's preprint.

How does protein folding change inside biomolecular condensates?

Our new preprint put forwards a framework for predicting this!! 🥳🥳🥳🥳 work by the talented @nathanieldhess.bsky.social

RBPscan: A quantitative in vivo tool for profiling RNA-binding protein interactions Kretov et al. introduce RBPscan, an RNA-editing-based platform that measures how RNA-binding proteins engage their targets in living cells. This approach quantifies the binding strength of protein-RNA...

I am thrilled to share our paper introducing RBPscan, a novel approach to profile RNA–protein interactions in living cells. Free access link at the end ⬇️ 🧵 1/
www.cell.com/molecular-ce...

I am excited to share a new review @cp-molcell.bsky.social written in collaboration with @tanjamittag.bsky.social , Mikayla Eppert, and Ambuja Navalkar where we review the current evidence for and against the role of density transitions in regulating transcription www.cell.com/molecular-ce...

Rethinking RNA-binding proteins: Riboregulation challenges prevailing views RNA-binding proteins (RBPs) are best known as effectors along the entire gene expression pathway and as constituents of RNA-protein machines such as t…

www.sciencedirect.com/science/arti...

Up now at #EMBOFISHingRNAs: Mainak Bose from the Indian Institute of Technology Kharagpur, India, with his keynote lecture on 'RNA/protein phase condensates' 💡

I’d love to be added. Could you please add me?

Congratulations 🎉

Can you please add me in this group. Thanks 😊

Characterizing protein sequence determinants of nuclear condensates by high-throughput pooled imaging with CondenSeq Nature Methods - CondenSeq is an imaging-based, high-throughput platform for characterizing condensate formation within the nuclear environment, uncovering the protein sequence features that...

In the nucleus, many intrinsically disordered proteins (IDPs) form condensates. What IDP sequence features drive this behavior? We developed CondenSeq, a high-throughput approach to measure nuclear condensate formation, and applied it to ~14,000 IDPs to find out!

rdcu.be/eq975

Congratulations 🎉

Omaya Dudin Interview with Omaya Dudin, who uses Ichthyosporea as models to study how and why unicellular organisms evolved multicellularity at the University of Geneva.

90% of you probably don’t need to read this.
But maybe some of you are curious & 10% will feel seen. Or a little less alone. This isn’t about seeking sympathy.
It’s about sharing something hard to say out loud;
partly to heal, partly in case someone needs to hear it too. (1/3)
tinyurl.com/DudinO

Congratulations

Thank you so much. It was inspiring and motivating as well. Keep motivated us through your research and thoughts.

Congratulations Sir

Hello Sir, added me please 🥺