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Reiner

@erlangen

p53, relationship between gut microbiome ⇄ health, nutrition science, ⚕medicine, PLOS blogs, PubMed HEALTH ⇄ RT≠Endorsement!

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30.09.2023
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Latest posts by Reiner @erlangen

People REVERSED their Cancer by eliminating Glycine and Serine - Brilliant Study!
People REVERSED their Cancer by eliminating Glycine and Serine - Brilliant Study! YouTube video by Physionic

Serine and glycine metabolism in cancer:
A serine-free diet in enhances antitumor immunity and promoting evasion via PD-L1 lactylation
www.cell.com/cell-metabol...
Serine starvation induces stress and p53-dependent metabolic remodelling in cancer cells
www.youtube.com/watch?v=0nP8...

09.03.2026 14:13 👍 0 🔁 0 💬 0 📌 0
Iron deficiency induces maturation-dependent loss of pancreatic β-cells - Nature Communications This study reports a maturation-dependent requirement for transferrin receptor -mediated iron uptake in pancreatic β-cells, whereby iron deficiency disrupts metabolic integrity and survival in develop...

Iron deficiency induces maturation-dependent loss of pancreatic β-cells
www.nature.com/articles/s41...
The findings suggest that iron deficiency can prevent the proper development of beta cells, contributing to reduced insulin secretion capacity
medicalxpress.com/news/2026-03...

09.03.2026 02:23 👍 4 🔁 1 💬 0 📌 0
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Insufficient Sleep Among US Adolescents Across Behavioral Risk Groups This study examines national trends in insufficient sleep from 2007-2023 and whether trends differed by demographic or behavioral risk subgroups.

nsufficient Sleep Among US Adolescents Across Behavioral Risk Groups
jamanetwork.com/journals/jam...
Teenagers are getting far less sleep now than they did in late 2000s, finds study
medicalxpress.com/news/2026-03...
There was a sharp rise in those getting five or fewer hours of sleep per night

09.03.2026 02:11 👍 1 🔁 1 💬 0 📌 0
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Coffee consumption is associated with intestinal Lawsonibacter asaccharolyticus abundance and prevalence across multiple cohorts - Nature Microbiology Coffee consumption is associated with the presence and abundance of a specific member of the human gut microbiome, Lawsonibacter asaccharolyticus, and changes to the plasma metabolome.

Coffee consumption is associated with intestinal Lawsonibacter asaccharolyticus abundance and prevalence
Published 18 Nov 2024
www.nature.com/articles/s41...
Lawsonibacter is known as a producer of butyrate that plays an important role in intestinal health
www.youtube.com/watch?v=NoWH...

08.03.2026 01:43 👍 7 🔁 3 💬 0 📌 1

The side effects of statins should not be underestimated
www.telegraph.co.uk/health-fitne...
Studies show that statin use is associated with lower testosterone levels. A meta-analysis found that statins can lower testosterone levels by approximately 3 to 4%

07.03.2026 03:05 👍 1 🔁 0 💬 0 📌 0
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DOP097 Emulsifier restriction is an effective therapy for active Crohn’s disease: the ADDapt trial - a multi-centre, randomised, double-blind, placebo-controlled, re-supplementation trial in 154 patie... AbstractBackground. Food additive emulsifiers result in bacterial dysbiosis, reduced intestinal mucus thickness, microbiota encroachment and increased perm

A low emulsifier diet (LED) is an effective treatment in mild/moderately active Crohn’s disease (CD)
academic.oup.com/ecco-jcc/art...
Emulsifiers are additives in processed foods: health risks for skin, gut and microbiome
www.ndr.de/ratgeber/ges...
Emulsifiers are not essential for nutrition

07.03.2026 02:45 👍 5 🔁 1 💬 0 📌 1
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Long-term thrombus-free left atrial appendage occlusion via magnetofluids - Nature In the presence of a sufficient magnetic field, magnetofluids can resist high-speed blood flow, offering a personalized and complete strategy for left atrial appendage occlusion.

Long-term thrombus-free left atrial appendage occlusion via magnetofluids
www.nature.com/articles/s41...
A safer, more effective atrial fibrillation treatment method using magnetic gel may be on the way
medicalxpress.com/news/2026-03...

06.03.2026 03:37 👍 0 🔁 0 💬 0 📌 0
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Surgeon: There is one thing ALL people who live past 90 have in common A surgeon has named the one habit that could be key to living well into your nineties - and it has nothing to do with diets or workouts.

Many people over 90 years old have one thing in common: They love a "post-meal walk" and take a 10-minute walk within about 30 minutes of eating dinner. This gentle exercise helps the body regulate blood sugar levels while also stimulating circulation
www.dailymail.co.uk/lifestyle/fi...

05.03.2026 17:47 👍 0 🔁 0 💬 0 📌 0
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Anticholinergic drug burden and incident cardiovascular events: a population-based study - BMC Medicine Background Drugs with anticholinergic properties are commonly used in older adults for various medical conditions, but the long-term cardiovascular consequences of cumulative exposure have not been we...

Common anticholinergic medicines may raise cardiovascular risk
link.springer.com/article/10.1...
People who use drugs with anticholinergic effects, drugs for urinary incontinence and common antihistamines, are at higher risk of developing cardiovascular disease
medicalxpress.com/news/2026-03...

04.03.2026 22:48 👍 3 🔁 3 💬 0 📌 0
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Zinc: A metallic shield against cardiac inflammation Abstract. Zinc (Zn) is a trace element essential for the function of over 10% of the human proteome, yet the average adult body contains only about two gra

Zinc
A metallic shield against cardiac inflammation
academic.oup.com/metallomics/...
Zinc plays a crucial role in300 enzymes, supports the immune system, protein & DNA production, regulates cell division
www.dailymail.co.uk/health/artic...
Anti-inflammatory properties and protects heart muscle cells

04.03.2026 14:55 👍 1 🔁 0 💬 0 📌 0
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The Dutch method: could this improve your sleep – and social life? Some may balk at Netherlanders’ ‘nothing to hide’ approach, but there is evidence their curtain customs could come with health benefits

The Dutch method: could this improve your sleep – and social life?
www.theguardian.com/lifeandstyle...

04.03.2026 03:12 👍 0 🔁 0 💬 0 📌 0
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Upregulation of reward mesolimbic activity and immune response to vaccination: a randomized controlled trial - Nature Medicine Upregulation of the ventral tegmental area via neurofeedback is associated with a stronger immune response to hepatitis B virus vaccination, and VTA upregulation is achieved through conscious positive...

Upregulation of reward mesolimbic activity and immune response to vaccination
www.nature.com/articles/s41...
Positive thinking could boost immune response to vaccines
www.theguardian.com/society/2026...
The result could indicate a potential connection with the placebo effect

04.03.2026 03:04 👍 0 🔁 0 💬 0 📌 0
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Plasma Proteome Profiling of Centenarian Across Switzerland Reveals Key Youth‐Associated Proteins Centenarians exhibit remarkable longevity and compression of morbidity making them an ideal population for uncovering proteins associated with successful aging. Using proteomics, we characterized the immune and cardiometabolic profiles of ...

Plasma Proteome Profiling of Centenarian Across 🇨🇭 Reveals Key Youth-Associated Proteins
pmc.ncbi.nlm.nih.gov/articles/PMC...
Swiss study has identified 37 proteins in centenarians' blood whose profile appears linked to slower ageing
www.unige.ch/medias/en/20...
☘️
www.t-online.de/gesundheit/a...

04.03.2026 00:35 👍 0 🔁 0 💬 0 📌 0
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Carcinogenic effects of long-term exposure from prenatal life to glyphosate and glyphosate-based herbicides in Sprague-Dawley rats - PubMed Glyphosate and GBHs at exposure levels corresponding to the EU ADI and the EU NOAEL caused dose-related increases in incidence of multiple benign and malignant tumors in SD rats of both sexes. Early-life onset and mortality were observed for multiple tumors. These results provide robust evidence sup …

Carcinogenic effects of long-term exposure from prenatal life to glyphosate and glyphosate-based herbicides
pubmed.ncbi.nlm.nih.gov/40490737/
Director Mandrioli was unexpectedly dismissed as head of the Cesare Maltoni Cancer Research Center (Ramazzini Institute)
taz.de/Nach-Glyphos...

03.03.2026 16:34 👍 2 🔁 0 💬 0 📌 0
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Arzt empfiehlt schon ab 30 Jahren 3 Maßnahmen gegen Demenz Veränderungen im Gehirn, die zu Demenz führen, beginnen oft Jahrzehnte bevor sich die Krankheit zeigt. Umso wichtiger ist es, früh vorzubeugen. Die richtigen Lebensgewohnheiten können das Demenzrisiko...

6 hours of sleep to cleanse the brain. During sleep, the brain is cleansed of metabolic waste products such as amyloid-β through the circulation of cerebrospinal fluid. Chronic sleep deprivation can impair this process and increase the risk of AD
www.focus.de/gesundheit/e...

03.03.2026 02:57 👍 1 🔁 0 💬 0 📌 0
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Amyloid Alpha: The Neglected Cousin of Amyloid Beta - PubMed For decades, amyloid β (Aβ) has been the principal therapeutic target for therapies of Alzheimer's disease (AD). An alternative processing product, known as P3, may form if the amyloid precursor protein is cleaved by α-secretase instead of β-secretase. This shorter peptide has received little attent …

Amyloid Alpha: The Neglected Cousin of Amyloid Beta
pubmed.ncbi.nlm.nih.gov/41758970/
The discovery that P3 is bioactive and potentially neurotoxic significantly expands our understanding of Alzheimer's pathology. Simply avoiding Aβ is insufficient
medicalxpress.com/news/2026-03...

03.03.2026 02:51 👍 2 🔁 1 💬 0 📌 0
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Real-time BioContact assurance and status monitoring using human body communication Reliable electrode-skin contact is essential for accurate biomedical signal acquisition, as poor contact leads to signal degradation and measurement e…

Real-time BioContact assurance and status monitoring using body communication
www.sciencedirect.com/science/arti...
Smart biomedical devices are transforming modern health care, using skin-mounted sensors to capture in-depth health information directly from the body
medicalxpress.com/news/2026-03...

03.03.2026 02:34 👍 0 🔁 0 💬 0 📌 0
Wissenschaft zeigt: Nichts lässt uns schneller altern als Muskelverfall (SO stoppst du ihn)
Wissenschaft zeigt: Nichts lässt uns schneller altern als Muskelverfall (SO stoppst du ihn) YouTube video by Alexander Seitz

Muskulatur als Langlebigkeitsorgan‼️
Science shows: Nothing ages us faster than muscle loss
www.youtube.com/watch?v=St7o...
In 2025, I will have completed my millionth push-up. There are very few days in my adult life when I haven't done push-ups

02.03.2026 14:50 👍 1 🔁 0 💬 0 📌 0
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Survivorship of modern total hip replacement to 30 years: systematic review, meta-analysis, and extrapolation of global joint registry data The estimated 92% 30-year survivorship of contemporary total hip replacement suggests that advances in bearing surface technology have greatly improved the long-term durability of total hip replacemen...

Survivorship of modern total hip replacement to 30 years: systematic review, meta-analysis, and extrapolation of global joint registry data
www.thelancet.com/journals/lan...
New hip replacements are likely to last at least 25 years, study suggests
medicalxpress.com/news/2026-02...

02.03.2026 02:18 👍 2 🔁 1 💬 0 📌 0
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Impact of flavan-3-ols on blood pressure and endothelial function in diverse populations: a systematic review and meta-analysis of randomized controlled trials AbstractAims. Flavan-3-ols, found in cocoa, tea, and certain fruits, show promise in improving blood pressure (BP) and vascular function, but are currently

Impact of flavan-3-ols on blood pressure and endothelial function in diverse populations: a systematic review and meta-analysis of randomized controlled trials
academic.oup.com/eurjpc/artic...
How dark chocolate can protect your heart, gut and brain
www.bhf.org.uk/informations...

02.03.2026 01:54 👍 3 🔁 1 💬 0 📌 1
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Skin androgens regulate Staphylococcus aureus pathogenicity via quorum sensing - Nature Microbiology Testosterone produced by skin cells enhances Staphylococcus aureus pathogenicity by activating quorum sensing, and a stereoisomer of testosterone that blocks this interaction inhibits bacterial cytoto...

Testosterone increases severity of bacterial skin infections, researchers discover
www.nature.com/articles/s41...
Men are more susceptible than women to skin infections caused by Staphylococcus aureus bacteria MRSA
medicalxpress.com/news/2026-02...

01.03.2026 02:21 👍 0 🔁 0 💬 0 📌 0
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Warum Proteine im Alter wichtig sind Mit zunehmendem Alter verändert sich der Körper – und damit auch der Nährstoffbedarf. Besonders wichtig ist es deshalb, ausreichend Proteine zu sich zu nehmen. Denn Eiweiß ist nicht nur Baustein unser...

he recommended daily intake of protein for people over 60 should increase from the current 0.8 g to 1.2 g per kg of body weight. This is due to age-related muscle los low protein diet
www.swr.de/leben/wohlbe...
The recommendations of the German Nutrition Society are highly outdated

01.03.2026 02:13 👍 0 🔁 0 💬 0 📌 0
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Discovery of an evolutionarily distinct evasin with dual CC and CXC chemokine inhibitory activity Previously identified tick evasins selectively inhibit either CC or CXC chemokines. Kunwar and Devkota et al. describe the first evasin that targets both families. AlphaFold modeling, molecular dynami...

Discovery of an evolutionarily distinct evasin with dual CC and CXC chemokine inhibitory activity www.cell.com/structure/fu...
How a tick could help prevent diseases like MS and cancer
medicalxpress.com/news/2026-02...
Chemokines can also overstimulate the immune system, resulting in MS

28.02.2026 03:40 👍 2 🔁 3 💬 0 📌 0
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Bifidobacterium longum and prebiotic interventions restore early-life high-fat/high-sugar diet-induced alterations in feeding behavior in adult mice - Nature Communications Here, the authors show that early-life high-fat/high-sugar diet induces sex-specific alterations in adult feeding behavior, hypothalamic transcriptome and blood metabolome, with Bifidobacterium longum...

Bifidobacterium longum APC1472 and prebiotic interventions restore early-life high-fat/high-sugar diet-induced alterations in feeding behavior in mice
www.nature.com/articles/s41...
Prebiotics and gut bacteria repair the brain after an unhealthy childhood diet
www.mdr.de/wissen/mediz...

26.02.2026 02:11 👍 3 🔁 1 💬 0 📌 0
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Indole-3 Acetate Limits Dysbiosis-Driven Diastolic Failure via Hcrt Neurons | Circulation Research BACKGROUND: The nervous, gastrointestinal, renal, and cardiovascular systems orchestrate ion-fluid homeostasis and impose reciprocal adaptations to hypertensive challenges. Mechanistic insight into th...

Indole-3 Acetate Limits Dysbiosis-Driven Diastolic Failure via Hcrt Neurons
www.ahajournals.org/doi/10.1161/...
Gut microbes control our heart via the brain
A metabolic product of bacteria in our gut controls heart function via brain cells
idw-online.de/de/news866439
Unknown gut-brain-heart axis

25.02.2026 01:27 👍 1 🔁 0 💬 0 📌 0
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Bryan Johnson - Wikipedia

The billionaire health guru Bryan Johnson (born 1977), who has nearly three million followers online, claims he intends to live for ever by making a series of extreme lifestyle changes. These include a regime of ~100 vitamins a day
en.wikipedia.org/wiki/Bryan_J...
www.dailymail.co.uk/health/artic...

23.02.2026 02:43 👍 2 🔁 1 💬 0 📌 0
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Mucosal vaccination in mice provides protection from diverse respiratory threats Traditional vaccines target specific pathogens, limiting their scope against diverse respiratory threats. We describe an intranasal liposomal formulation combining toll-like receptor (TLR) 4 and 7/8 l...

Mucosal vaccination in mice provides protection from diverse respiratory threats
www.science.org/doi/10.1126/...
Single vaccine could protect against all coughs, colds and flus
www.bbc.com/news/article...
The vaccine also protects against Staphylococcus aureus and Acinetobacter baumannii

21.02.2026 03:27 👍 12 🔁 3 💬 0 📌 0
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Stability of epigenetic transgenerational inheritance of adult-onset disease and parturition abnormalities | PNAS Previous research on the generational stability of epigenetic transgenerational inheritance was conducted through a ten-generation study of all tra...

A single exposure to a toxic fungicide during pregnancy can increase the risk of disease for 20 subsequent generations
www.pnas.org/doi/10.1073/...
Toxic exposure creates disease risk over 20 generations, epigenetic inheritance study suggests
medicalxpress.com/news/2026-02...

20.02.2026 19:30 👍 0 🔁 0 💬 0 📌 0
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New evidence reveals streptococcus anginosus drives gastric cancer development - ecancer A recent study published in the medical journal Gut has revealed a novel cancer-promoting mechanism of Streptococcus anginosus (Sa). The research s

New evidence reveals streptococcus anginosus drives gastric cancer development
ecancer.org/en/news/2757...
Bacteria in the mouth: Study reveals previously unknown cancer trigger
www.fr.de/panorama/bak...
Streptococcus anginosus-derived methionine promotes gastric cancer progression

19.02.2026 15:31 👍 5 🔁 1 💬 0 📌 0
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Innate immune priming by n-dodecyl-β-D-maltoside in murine models of bacterial and viral infection DDM is a first-in-class, non-PAMP immune primer that rapidly and safely induces neutrophil-driven protection against AMR bacterial sepsis and viral infection, offering a host-directed strategy for cro...

Innate immune priming by n-dodecyl-β-D-maltoside (DDM) in murine models of bacterial and viral infection
www.thelancet.com/journals/ebi...
Blocking both drug-resistant bacteria and influenza with a broad-spectrum infection prevention approach
medicalxpress.com/news/2026-02...

17.02.2026 03:04 👍 4 🔁 3 💬 0 📌 0