Sara Alonso

We close out 2025 with a review by @ananya-p.bsky.social & @tingtingli1.bsky.social in @gutmicrobes.bsky.social discussing the influence of the #microbiota on #gdTcell compartments within the gut, since populations and function differ in the #epithelium and lamina propria. 1/n

It’s a #gdTcell flavored #MucosalMonday! @saraalonsomera.bsky.social & I chat about the magic of our favorite cell type and our recent paper elucidating the role of the microbiota in driving gd IEL regulatory function on this month’s @societymucosalimm.bsky.social podcast.
@sinaiimmuno.bsky.social

@repdangoldman.bsky.social, please draw attention to & speak up against political appointees in place of civil servants for #NIH Institute Directors. This is just the next tactic to prevent us from making advances and curing disease. #standupforscience

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Microbiota promote enhanced CD39 expression in γδ intraepithelial lymphocytes through the activation of TCR and IL-15 signaling in this work from @saraalonsomera.bsky.social @edelblumlab.bsky.social and colleagues: www.mucosalimmunology.org/article/S193...

Microbiota promote enhanced CD39 expression in γδ intraepithelial lymphocytes through the activation of TCR and IL-15 signaling Intraepithelial lymphocytes expressing the γδ T cell receptor (γδ IEL) provide continuous surveillance of the intestinal epithelium. We report that mi…

📚NEW #gdTcell PAPER ALERT! 'Microbiota promote enhanced CD39 expression in γδ intraepithelial lymphocytes through the activation of TCR and IL-15 signaling' is now out in @mucosalimmunol.bsky.social! #gastrosky #GIsky #IBDsky Join us for a Bluetorial 🧵...

Thank you Payal!

So grateful for my time in the Edelblum lab and so excited for what's to come!

Great night out at #NYC @crohnscolitisfdn.bsky.social #TakeStepsWalk with the lab! The Mount Sinai IBD Center raised almost $2,500 for #IBD research. Bonus: I met Blake Lively & Ryan Reynolds (both very nice) on the ferry ride home! @sinaiimmuno.bsky.social

Thank you!

Thank you Seth! It was so good to see you :)

Thank you to the organizers for inviting me to speak and for choosing me for this award! I had a lovely time in Toronto learning so much about my favorite cells ❤️ #gd2025

As expected, #gd2025 is as delightful as ever! Glad I could bring Irving & @saraalonsomera.bsky.social to hang out with our #gdTcell crew including @sarinaravens.bsky.social, @coffeltlab.bsky.social, @immunowolf.bsky.social, and Julie Jameson 🤩 Miss you @lydialynch.bsky.social!

Congrats @ananya-p.bsky.social !!!

Congrats to @ananya-p.bsky.social on her outstanding Master’s defense on #gdTcell migration! 🍾🎉 We’re looking forward to another couple of years with Ananya as she takes on the new role of senior grad student @sinaiimmuno.bsky.social 😁

Thank you @edelblumlab.bsky.social for being an amazing mentor and thank you @nbgolovchenko.bsky.social for being the best colleague and friend I could have asked for 😊. These past 5 years have been incredible and I'm excited for what's to come!

📣 New preprint drop! In #ScienceImmunology, we found that regulatory #CD39 γδ IELs are reduced in #IBD, now @saraalonsomera.bsky.social shows that gut #microbiota promote enhanced CD39 expression in γδ IELs through #TCR and IL-15 activation. #gdTcells #GIresearch #Gastrosky @sinaiimmuno.bsky.social

Microbiota promote enhanced CD39 expression in γδ intraepithelial lymphocytes through the activation of TCR and IL-15 signaling Intraepithelial lymphocytes expressing the γδ T cell receptor (γδ IEL) provide continuous surveillance of the intestinal epithelium. We report that mice harboring a microbiota-specific hyperproliferat...

If you read our #ScienceImmunology paper and want to know how the #microbiota induces #CD39 to promote a #gdTcell #immunoregulatory phenotype, check out our new #preprint!

two men are riding a bicycle with a basket on it . ALT: two men are riding a bicycle with a basket on it .

#Bluetorial: In our latest paper on #gdTcells and #IBD in #ScienceImmunology we found that γδ IEL number and regulatory function are severely compromised BEFORE ileal inflammation occurs, suggesting that γδ IELs may maintain IEL homeostasis in response to a pro-inflammatory microenvironment. 1/n

@sinaiimmuno.bsky.social just gained a rockstar #PhD student with the acceptance of @ananya-p.bsky.social! Come see why we’re so lucky that Ananya will be joining us for a few more years at the APS Summit. She’ll be presenting two flashtalks (#GIL Trainee Symposium & Forte) on #gdTcell #migration 😍

Congratulations to Dr. Sara Alonso on a spectacular defense! 👏 🍾 Sara is a powerhouse of #gdTcell #immunometabolism data in the lab. We can’t wait to share the #preprint of her thesis work on #gdTcells and #microbiota with you later this week. @sinaiimmuno.bsky.social