A cGAS-mediated mechanism in naked mole-rats potentiates DNA repair and delays aging | Science www.science.org/doi/10.1126/...
A cGAS-mediated mechanism in naked mole-rats potentiates DNA repair and delays aging | Science www.science.org/doi/10.1126/...
Excited to be in Kumamoto for #ISEH2025!! π©Έ I get to share my PhD work (so far) at poster #24 tomorrow and poster #3220 on Friday afternoon - please come by to chat about RNA binding proteins, erythropoiesis, and iron metabolism :)
FlyBase needs your help! We ask that European labs continue to contribute to Cambridge, UK FlyBase, whereas US and other non-European labs can contribute to US FlyBase. For more information and how to donate: wiki.flybase.org/wiki/FlyBase...
Iron-loaded Red Blood Cells undergo a lipid peroxidation process akin to ferroptosis during storage in the blood bank. We now show that they also harbor a functional GPX4, and common SNPs, genetic or pharmacological manipulation impact transfusion outcomes www.sciencedirect.com/science/arti...
New in @natbiotech.nature.com: a team led by scientists at MSK and βͺUniversity of Toronto have developed a new platform to facilitate the study of RNA-biding proteins (RBPs) across hundreds of species of plants, insects, and animals.
UHN is grateful and honoured to have called Dr. James Till, one of the fathers of stem cell science, a valued member of TeamUHN.
His many colleagues and students continue their work in his legacy, furthering stem cell science and cancer research, and improving patient outcomes.
!!!
WOOO!! πππ Congrats Steph!!
Thrilled to share the first pre-print from our lab! We tackled a big question: Why are some pediatric leukemias extremely aggressive? We explored the developmental origins of fusion-driven acute myeloid leukemia (AML). Let's dive in! #AML #NUP98 A thread... n/13
What protects individuals from developing blood cancers?
Thrilled to share my work in @bloodgenes.bsky.social lab, describing inherited resilience protecting blood stem cells from clonal hematopoiesis by modifying RNA regulation. π§΅π (1/n)
www.biorxiv.org/content/10.1...
Congratulations to our Senior Scientists Drs. John Dick and Jean Wang, and Jayne Danska from @sickkidsto.bsky.social
on receiving the Inventor of the Year Award @uhntoronto.bsky.social. Their research has advanced a cancer immunotherapy now in global Phase II trials for hematological malignancies.
Well deserved award for Dr. Gordon Keller! Gordon was a member of my thesis committee when I was a PhD student and his helpful suggestions made me a better scientist :)
www.isscr.org/isscr-news/g...
Had the best time in SLC learning lots about iron & heme last week!! So grateful for the fantastic program that the CIHD faculty & staff put together and to have met so many cool people :))
Cristiana OβBrien is our fourth #TeamUHNWomen feature and a doctoral student at @pmresearch-uhn.bsky.social.
Learn about why she is grateful to be in science and what it means to be a woman in her field β‘οΈ www.uhnresearch.ca/news/shining...
So excited to visit Utah and listen to all these cool talks in March!!
Erasmus MC Hematology Lecture speaker lineup never fails to impress! #hemesky π§ͺπ©Έ mcusercontent.com/71bcc0f3bb8a...
Are you from #HamOnt or surrounding area? Have #asthma or wheezing during exercise? Want to take part in research at @mcmasteruniversity.bsky.social to discover new treatments ? Email asthma@mcmaster.ca to learn more! (Please share with yoru networks) #pulmsky www.linkedin.com/posts/macres...
Excited to share a major breakthrough from the lab! D&D-seq is a new technology that bridges a key gap in single-cell multi-omics/genomics : the ability to map DNA:Protein interactions (e.g., TFs or chromatin remodellers). Led by Ivan Raimondi, Wei-Yu Chi and Sang-Ho Yoon
Mitochondria consist of networks of cylindrical tubes, right? Not necessarily! - in our new preprint, @gavsturm.bsky.social investigates how mitochondria transiently adopt a beads-on-a-string morphology
www.biorxiv.org/content/10.1...
Bioart, courtesy of the NIH. All images are in the public domain and available for download as high-quality SVGs.
bioart.niaid.nih.gov
Oh rats! Thanks for letting me know - hopefully I can catch the next one if you visit again! :)
Hello! Would love to attend your talk (if itβs open to the wider UofT community/hasnβt already happened) - could I ask when/where itβs being hosted? :) Thank you!
Seated (online) and ready to listen!! πͺ
Safe travels!! And happy 60th to your dad! π
Iβm thrilled to share a collaborative story from @Mendell_lab and Jan Erzberger labs, led by postdoc extraordinaire Xiaoqiang Zhu. We showed that in addition to their canonical decoding function, tRNAs play a key role in regulating mRNA stability during translation!
www.science.org/doi/10.1126/...
You as well!! π«
π¨ Save the Date!π¨ ISEH is heading to Kumamoto, Japan for #ISEH2025. Check out our confirmed speakers so far and mark your calendars for a great program you won't want to miss β‘οΈ iseh.org/iseh2025
Migrating! Happy to see lots of favourite blood folks already here :)