4. The inherited memory correlates with increased vitellogenin transcription.
5. Mutants lacking the primary vitellogenin receptor are defective in transgenerational inheritance.
Together, the multigenerational effect of diet-derived vitamin B12 highlights the significance of vitellogenin provisioning in transgenerational responses.
Our work reveals 5 major findings:
1. Bacteria-derived vitamin B12 is both necessary and sufficient for transgenerational memory.
2. Specific B12 concentrations are required to trigger this effect.
3. B12 mediates its effects through methionine synthase.
Our second preprint is out!
My first PhD paper is finally out!
For the first time, I uncovered the involvement of microRNAs in epigenetic memory! Watch out for at least three more follow-up stories revolving around microRNA targets, bacterial inducing agent, and the adaptive aspects of transgenerational epigenetic inheritance.
