Dr. Hernán López-Schier

From Tolstoy to the Mathematics of Happiness The opening line of Leo Tolstoy’s Anna Karénina is so good that it has the sharpness of a mathematical theorem.

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I do not have a lot of material possessions, and this one is one of my most cherished. It is a hard-copy reprint of a Prof. Peter A. Lawrence FRS 1966 publication. Signed and dedicated (in Spanish), after a long discussion that he and I (still a PhD student) had about planar polarity many years ago

Approaching Multiple Sclerosis with Better Diagnostics and Digital Twins Multiple Sclerosis is often called the disease of a thousand faces, which explains why its current diagnosis lags behind those for other conditions.

lopezschier365.substack.com/p/approachin...

Are You Trying to Win a Debate, or Solve a Problem? The "Art of Thoughtful Disagreement" is a concept most prominently associated with Ray Dalio. When done well, it is one of the most powerful tools that we have to make better decisions about problems.

Are You Trying to Win a Debate, or Solve a Problem?

The "Art of Thoughtful Disagreement" is a concept most prominently associated with Ray Dalio. When done well, it is one of the most powerful tools that we have to make better decisions about problems.

lopezschier365.substack.com/p/the-art-of...

How Artificial Intelligence Works (in “very, very” short) Modern AI can feel like a magic trick. It generates stunning art, writes human-like text, writes code and devises novel strategies for complex games. But the truth is that its most powerful secret is

lopezschier365.substack.com/p/how-artifi...

Very well-conducted work in zebrafish by my colleagues at the @adrianjacobo.bsky.social laboratory www.biorxiv.org/content/10.6...

Which also confirms and expands the earlier discovery by Mike Deans and collaborators in mice elifesciences.org/articles/84910

Tomorrow Will Not Be Different Dysthymia is a form of low-grade depression that never quite leaves. Let’s discuss why it seeps throughout every aspect of life and is so notoriously hard to treat.

lopezschier365.substack.com/p/tomorrow-w...

Hernan Lopez-Schier (@yyou365) Bad sleep hits the collective purse. A Epidemiology and Economic Burden of Sleep Disorders in Europe study (https://onlinelibrary.wiley.com/doi/10.1111/ene.70463) that was published just five days ag...

substack.com/@yyou365/not...

Self-driving microscopes YouTube video by Cephla

How self-driving cars motivated us to build a universal diagnostics platform for malaria/Tb. The arc of technology is unpredictable at best.

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The Upgrade of a Mother’s Brain The brain of pregnant women undergoes profound plastic changes that will impact herself as well as her newborn. Here is a deep dive into this important, fascinating, and often misunderstood process.

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Yerba Mate vs. Matcha. The Lowdown Matcha is powdered green tea coming from Asia. Yerba mate is a tea-like infusion from South America. At first glance, matcha and yerba mate seem to occupy the same niche, but they are very different.

lopezschier365.substack.com/p/yerba-mate...

The Mystery of Multiple Sclerosis Multiple sclerosis (MS) is an unpredictable disease that remains one of neurology's most perplexing puzzles. Understanding MS means grappling with a condition that can look entirely different from one

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Local control of cellular proliferation underlies neuromast regeneration in zebrafish - PubMed Biological systems are never in equilibrium, yet they maintain stability in the face of continuous external disturbances. A prime example of this is organ regeneration, during which organs are reliably rebuilt through controlled cellular proliferation. In this study, we employ a cell-based computati …

New publication from the lab! Very excited for a the new work in collaboration with Osvaldo Chara.

pubmed.ncbi.nlm.nih.gov/41617078/

How do living systems remain stable ? We found a local feedback that acts like a quorum-sensing system, ensuring organs regrow to the right size.

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😱

Phil Collins - Sussudio (Official Music Video) [HD Upgrade] YouTube video by Phil Collins

I know, but let me light up your day www.youtube.com/watch?v=r0qB...

Weak Ties with Strong Pull
The American sociologist Mark Granovetter argues that loose connections linking different networks facilitate the spread of ideas and open new professional opportunities. But why?

lopezschier365.substack.com/p/weak-ties-...

Flora in Ras Al Khaimah. Makes you wonder how much more life thrives in the "harsh" desert

Charlie Munger’s Lollapalooza Effect

Big events are rarely monocausal. Cause-Effects non-linearity happens when multiple forces align in the same direction and are not simply additive. Why understanding how forces compound is a new survival skill.

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Scientists at the State Key Laboratory of the Chinese Academy of Sciences in Beijing, China, have just developed a revolutionary soft biodegradable implant for wireless long-distance sensing.

lopezschier365.substack.com/p/why-your-b...

Artificial Intelligence and the Black Swan Can AI predict Black Swan events better than humans do? Not really, but it can make us less blind to them.

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How AI will find the next MVP Artificial intelligence is poised to redefine sports talent scouting by measuring innate ability anywhere in the world.

lopezschier365.substack.com/p/how-ai-wil...

And The Trophy Goes To The Digital Athlete.

How a synergistic convergence of new technologies is rewriting the playbook for elite performance. The result will be significant gains with a lot less pain.

lopezschier365.substack.com/p/and-the-tr...

Culture and Customs Eat Artificial Intelligence for Breakfast.

If AI is not presented correctly, it could be mauled by cultural norms.

lopezschier365.substack.com/p/culture-an...