Noelle L’Etoile's Avatar

Noelle L’Etoile

@girlsinscience

worms, brains, science for all, 🏳️‍🌈🏳️‍⚧️ally, DEMILITARIZE UCPD. STEM needs immigrants UCSF Prof posts- my own. letoilelab.net

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Latest posts by Noelle L’Etoile @girlsinscience

The U.S. economy lost 92,000 jobs in February.

A record number of Americans are withdrawing from their 401ks to cover expenses.

Americans owe $18.5 trillion in debt — an historic high.

Meanwhile, the wealth of America's 935 billionaires soared by $1.5 trillion in 2025.

“Golden Age” for whom?

08.03.2026 20:01 👍 3852 🔁 1341 💬 148 📌 66
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Americans aren't facing a democratic collapse. We’re living in its aftermath | Eric Reinhart The US was an oligarchy well before Trump’s first term. Recognizing this reality is essential to building a true democracy

“Democracy … begins when people decide they will not abandon one another.”

We are under the illusion that we have ever had a true democracy. Trump is the logical next step in the evolution of a system that was never democratic.

We need a grassroots movement.
www.theguardian.com/global/comme...

08.03.2026 17:13 👍 4 🔁 0 💬 0 📌 0
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At Largest ICE Detention Camp, Staff Bet on Detainee Suicides, AP Reports Camp East Montana has received several 911 calls in the span of five months about immigrants trying to harm themselves.

Staff at the nation’s largest Immigration and Customs Enforcement detention facility have placed bets on which detainee will be the next to die by suicide, according to new reporting from the Associated Press based on 911 calls and detainee accounts.

07.03.2026 21:00 👍 9251 🔁 6033 💬 604 📌 1533
An image of Bernal hill from Van Ness Avenue with a red arrow point to a nearly invisible sign that says “Stand Up for Science SF”

An image of Bernal hill from Van Ness Avenue with a red arrow point to a nearly invisible sign that says “Stand Up for Science SF”

Today is National #StandUpforScience day. Here is my failed contribution. You have to zoom way the $&@#% in.

07.03.2026 19:42 👍 6 🔁 2 💬 1 📌 0
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RIP to Jesse Jackson. His funeral is today. I wanted to share this clip from his appearance on Sesame Street in 1971. His important words ring just as true today as they did back then.

06.03.2026 19:01 👍 8372 🔁 2253 💬 139 📌 127
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ICE arrests US Spanish-language news outlet reporter without warrant Estefany Rodriguez Florez of Nashville Noticias, who had produced reports that were unflattering to ICE, was arrested during traffic stop

www.theguardian.com/us-news/2026...

07.03.2026 00:55 👍 0 🔁 0 💬 0 📌 0
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ICE arrested an Oregon shop owner who had her green card in her pocket: ‘They didn’t care’ Juanita Avila later helped expose ICE’s ‘arrest first, justify later’ tactics in a lawsuit that won a major victory for immigrants’ rights

www.theguardian.com/us-news/2026...

07.03.2026 00:36 👍 1 🔁 1 💬 1 📌 0
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Charge Epstein's Co-Conspirators! Recent documents released by the DOJ reveal eight people listed as co-conspirators: Les Wexner, billionaire and former CEO of Victoria’s Secret; Lesley Groff, Epstein’s longtime secretary; the late mo...

This cause is close to my heart - please sign: sign.moveon.org/petitions/ch...

07.03.2026 00:07 👍 0 🔁 0 💬 0 📌 0
Page 2 of letter by Daniel Swain. It begins: constructive suggestions regarding how the already remarkable institutional efficiency and societal impact of NCAR could be further enhanced through increased (not decreased) federal support in the years to come.
Please note: To ensure the highest level of technical rigor, this response focuses exclusively on the core atmospheric and natural hazard science topics within the author’s primary domain of expertise; for this reason, I have omitted a response to Topic 4 (Space Weather)."


NCAR weather modeling and atmospheric observing capabilities
a) Management and operations of weather-related observational platforms, modeling and science as a stand-alone activity.
The proposed management of weather-related research as a stand-alone activity is a scientifically regressive path that ignores the fundamental physical reality of the Earth system. Modern atmospheric science has demonstrated (largely, it is worth noting, due to groundbreaking researc

Page 2 of letter by Daniel Swain. It begins: constructive suggestions regarding how the already remarkable institutional efficiency and societal impact of NCAR could be further enhanced through increased (not decreased) federal support in the years to come. Please note: To ensure the highest level of technical rigor, this response focuses exclusively on the core atmospheric and natural hazard science topics within the author’s primary domain of expertise; for this reason, I have omitted a response to Topic 4 (Space Weather)." NCAR weather modeling and atmospheric observing capabilities a) Management and operations of weather-related observational platforms, modeling and science as a stand-alone activity. The proposed management of weather-related research as a stand-alone activity is a scientifically regressive path that ignores the fundamental physical reality of the Earth system. Modern atmospheric science has demonstrated (largely, it is worth noting, due to groundbreaking researc

Page 3 of letter by Daniel Swain. It begins: b) Management and operations of weather-related observational platforms, modeling and science as combined with other NSF investments/facilities.
The highly specialized nature of the NCAR-Wyoming Supercomputing Center (NWSC) infrastructure represents an extraordinary value proposition that cannot be replicated by combining it with more generalized NSF programs. The NWSC is not a generic high-performance computing (HPC) facility; it is a laboratory uniquely optimized for atmospheric science workflows, with a hardware and storage architecture specifically designed to handle the massive, high-bandwidth data demands of Earth system modeling. Furthermore, its model of providing an excellent, free-at-point-of-use technical support team ensures that the focus remains on the science rather than the overhead of systems administration. This centralized expertise allows individual researchers, smaller labs, and even entire universities—who would otherwi

Page 3 of letter by Daniel Swain. It begins: b) Management and operations of weather-related observational platforms, modeling and science as combined with other NSF investments/facilities. The highly specialized nature of the NCAR-Wyoming Supercomputing Center (NWSC) infrastructure represents an extraordinary value proposition that cannot be replicated by combining it with more generalized NSF programs. The NWSC is not a generic high-performance computing (HPC) facility; it is a laboratory uniquely optimized for atmospheric science workflows, with a hardware and storage architecture specifically designed to handle the massive, high-bandwidth data demands of Earth system modeling. Furthermore, its model of providing an excellent, free-at-point-of-use technical support team ensures that the focus remains on the science rather than the overhead of systems administration. This centralized expertise allows individual researchers, smaller labs, and even entire universities—who would otherwi

Page 4 of letter by Daniel Swain. It begins: NCAR Mesa Lab (located in Boulder, Colorado)
a/b) Ownership of the NSF NCAR Mesa Lab building for public and private use.
Far more than just an office building, NSF NCAR Mesa Lab is an iconic and purpose-built facility designed specifically for the study of atmospheric science. Its position at the physical interface of the Rocky Mountain foothills and the Great Plains is a deliberate reflection of its mission, serving as a visible symbol—in an iconically American setting—of the federal government's enduring commitment to science in service of society. For many in the field, including myself, the Mesa Lab holds singular importance as a focal gathering point for the global atmospheric science community. My own early career exposure to weather and Earth system modeling, in fact, occurred within these walls, and I have long felt that the facility’s architecture and location inspire a necessary sense of awe regarding the atmosphere’s complexity a

Page 4 of letter by Daniel Swain. It begins: NCAR Mesa Lab (located in Boulder, Colorado) a/b) Ownership of the NSF NCAR Mesa Lab building for public and private use. Far more than just an office building, NSF NCAR Mesa Lab is an iconic and purpose-built facility designed specifically for the study of atmospheric science. Its position at the physical interface of the Rocky Mountain foothills and the Great Plains is a deliberate reflection of its mission, serving as a visible symbol—in an iconically American setting—of the federal government's enduring commitment to science in service of society. For many in the field, including myself, the Mesa Lab holds singular importance as a focal gathering point for the global atmospheric science community. My own early career exposure to weather and Earth system modeling, in fact, occurred within these walls, and I have long felt that the facility’s architecture and location inspire a necessary sense of awe regarding the atmosphere’s complexity a

Page 1 of letter by Daniel Swain. It begins: Dear Acting Director Stone and the NSF NCAR restructuring team:

I am writing to provide a formal response to the Request for Information (RFI) regarding the proposed restructuring of the NSF National Center for Atmospheric Research (NCAR) and its critical weather science infrastructure contained within the January 23, 2026 Dear Colleague Letter (DCL) entitled “NSF Intent to Restructure Critical Weather Infrastructure.” I submit these comments in my professional capacity as an atmospheric research scientist within the University of California, where my research focuses on the physics and dynamics of atmospheric processes related to extreme weather events and their role in shifting natural hazard and disaster risk.

My perspective is informed by a public-sector career dedicated to bridging the gap between fundamental atmospheric research and real-world application in an academic context, with a particular focus on understanding and mitigating

Page 1 of letter by Daniel Swain. It begins: Dear Acting Director Stone and the NSF NCAR restructuring team: I am writing to provide a formal response to the Request for Information (RFI) regarding the proposed restructuring of the NSF National Center for Atmospheric Research (NCAR) and its critical weather science infrastructure contained within the January 23, 2026 Dear Colleague Letter (DCL) entitled “NSF Intent to Restructure Critical Weather Infrastructure.” I submit these comments in my professional capacity as an atmospheric research scientist within the University of California, where my research focuses on the physics and dynamics of atmospheric processes related to extreme weather events and their role in shifting natural hazard and disaster risk. My perspective is informed by a public-sector career dedicated to bridging the gap between fundamental atmospheric research and real-world application in an academic context, with a particular focus on understanding and mitigating

I just submitted my letter to NSF responding to its proposal to dismantle the National Center for Atmospheric Research (NCAR). I argue that doing so would be an astonishing and avoidable misstep, and that federal support for the institution should in fact be *increased.* [1/4]

06.03.2026 04:25 👍 521 🔁 165 💬 4 📌 3

Now threading these... [from a couple weeks ago] Second paper acceptance of the year to #wundergrad Amelie L'Etoile-Goga! Her lovely quantification of #Mesodinium grazing preferences is coming out soon in The Journal of Phycology.

03.03.2026 20:49 👍 1 🔁 1 💬 1 📌 0
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Feds asked New Mexico to halt Jeffrey Epstein Zorro Ranch sex trafficking probe, records show Former AG says feds halted New Mexico’s Epstein inquiry without sharing promised evidence as state reopens Zorro Ranch i

New reporting finds that Trump's DOJ took over and quashed a state investigation into Epstein's New Mexico ranch in 2019.

As the walls close in on Trump, he'll do anything — including launch full-scale wars — to distract the public.

02.03.2026 23:31 👍 3545 🔁 1655 💬 133 📌 97
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🍿 MTG still making sense. This past year really has felt like we’re living in the upside down.

03.03.2026 02:00 👍 8769 🔁 1647 💬 438 📌 117
Top: Example confocal micrograph showing astrocyte expression of S100β (green), Cre-RFP (magenta), and H1R mRNA (cyan). Left: summed z-projection of all three confocal channels. Middle: RNAscope detected H1R mRNA with white and yellow arrows indicating example WT (S100β+/RFP−/H1R+) and cKO (RFP+/H1R−) soma regions of interest (ROIs), respectively. Right: Cre-RFP expression (top, magenta) and S100β expression (bottom, green). Scale bars = 10 μm. Bottom: Example confocal micrograph showing astrocytic Cre-RFP (magenta), neuronal NeuN (green), and nuclear marker DAPI (blue). Left: summed z-projection of all three confocal channels. Middle: astrocytic Cre-RFP signal with astrocyte soma ROIs overlaid. Right: NeuN signal with astrocyte soma ROIs overlaid. Scale bars = 50 μm.

Top: Example confocal micrograph showing astrocyte expression of S100β (green), Cre-RFP (magenta), and H1R mRNA (cyan). Left: summed z-projection of all three confocal channels. Middle: RNAscope detected H1R mRNA with white and yellow arrows indicating example WT (S100β+/RFP−/H1R+) and cKO (RFP+/H1R−) soma regions of interest (ROIs), respectively. Right: Cre-RFP expression (top, magenta) and S100β expression (bottom, green). Scale bars = 10 μm. Bottom: Example confocal micrograph showing astrocytic Cre-RFP (magenta), neuronal NeuN (green), and nuclear marker DAPI (blue). Left: summed z-projection of all three confocal channels. Middle: astrocytic Cre-RFP signal with astrocyte soma ROIs overlaid. Right: NeuN signal with astrocyte soma ROIs overlaid. Scale bars = 50 μm.

What's the function of #histamine -1-receptors (H1Rs) on cortical astrocytes? @kiraposkanzer.bsky.social & co show that astrocytic H1R signaling modulates Ca2+ activity, extracellular adenosine & REM #sleep, revealing a key #astrocyte role in sleep-wake regulation @plosbiology.org 🧪 plos.io/4gRj9Ap

03.10.2025 08:21 👍 10 🔁 5 💬 0 📌 0
Today should be your 38th birthday..
When you lose your son you lose more than a child you lose a piece of your heart and your joy. Life is forever altered, and nothing can ever fill that space. Yet in my soul, he remains, my precious boy, forever loved. His laughter, his smile, and his love are woven into who I am. My love for him will never fade. Yor are my pride and my joy - you've made a change that cannot be broken..

Today should be your 38th birthday.. When you lose your son you lose more than a child you lose a piece of your heart and your joy. Life is forever altered, and nothing can ever fill that space. Yet in my soul, he remains, my precious boy, forever loved. His laughter, his smile, and his love are woven into who I am. My love for him will never fade. Yor are my pride and my joy - you've made a change that cannot be broken..

Alex's mom on his 38th birthday.

02.03.2026 00:24 👍 21314 🔁 5344 💬 471 📌 315

If a trans person were caught jaywalking Republicans would be ranting about it every chance they got, meanwhile a trans person JUMPED INTO LAKE MICHIGAN IN THE WINTER AND RESCUED A STRANGER’S BABY and it’s crickets.

26.02.2026 20:41 👍 1797 🔁 573 💬 20 📌 3

I might hang it upside down - I love the wicked smile

28.02.2026 00:41 👍 2 🔁 0 💬 0 📌 0
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Iranian regime pressures families of slain protesters to bury truth of crackdown | CNN Amirhossein Saedi’s father had urged him to stay home. The protests sweeping Iran were growing more dangerous by the day, and the 19-year-old computer science student was still recovering from illness...

Brutal crackdowns aimed at silencing families of protestors that were killed by state forces are happening in Iran but it doesn’t get a lot of coverage:
www.cnn.com/2026/02/26/m... www.cnn.com/2026/02/26/m...

27.02.2026 16:40 👍 0 🔁 0 💬 0 📌 0
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Help! We're struggling to choose between these two images of #Mesodinium #karmachamaeleon and its cryptophyte prey, one more "documentary" and one more "action shot," as cover image submissions (to a society journal). If you were an editor, which one would more likely catch your eye? #protistsonsky

25.02.2026 23:54 👍 32 🔁 6 💬 13 📌 0
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My vote is for this one - I’ve had it framed in anticipation! It’s my birthday present from one of the authors’ dad.

27.02.2026 16:20 👍 5 🔁 2 💬 1 📌 0
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Home Reporting on San Francisco's most critical issues: police reform, corruption, education, public health, housing and homelessness.

Mission Local SF missionlocal.org

27.02.2026 04:32 👍 0 🔁 0 💬 0 📌 0

And buried within the story is a snippet of an interview with a survivor who was thirteen years old when Epstein brought her to Trump who then pushed her head down onto his exposed penis which she bit.

27.02.2026 04:28 👍 1 🔁 0 💬 0 📌 0
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Epstein Files: NPR Finds 53 Missing ‘Trump’ Pages — the DOJ Has No Explanation NPR finds 53 Epstein file pages missing from the DOJ release, deepening questions about transparency in Trump’s own Justice Department.

AT LEAST 53 PAGES OF FBI INTERVIEW SUMMARIES AND NOTES APPEAR TO EXIST IN THE TRUMP/EPSTEIN FILES BUT ARE NOT IN THE PUBLIC DATABASE

26.02.2026 15:20 👍 2618 🔁 1069 💬 168 📌 57
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Nurul Amin Shah Alam crossed oceans to flee unimaginable violence, only to die here — where he should have been safe.

The cruelty is endless.

26.02.2026 17:45 👍 6202 🔁 2687 💬 342 📌 221

And she didn’t stop the open secret. How were the wives of the men not aware? Epstein invited them along with - possibly using them as cover for the leery parents of 13 yos they planned to rape.
Is Clinton and the duped wives collecting their resources to fund his victims legal and security needs?

26.02.2026 20:09 👍 0 🔁 0 💬 0 📌 0

A Columbia Neuroscience student was kidnapped from her student housing by ICE after misrepresenting themselves as police officers looking for a missing person.
As neuroscientists- we need to protest this in any way we can.

26.02.2026 19:28 👍 3 🔁 2 💬 0 📌 0
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BREAKING: Protests have erupted at Columbia University after the school says DHS agents detained a student after making "misrepresentations to gain entry" to building.

26.02.2026 19:19 👍 5926 🔁 1945 💬 109 📌 129
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Justice Department withheld and removed some Epstein files related to Trump An NPR investigation finds the public database of Epstein files is missing dozens of pages related to sexual abuse accusations against President Trump.

This needs to be amplified as much as possible on all platforms.

Not sure the algorithms on all platforms (X, FB) will allow but it has to happen.

www.npr.org/2026/02/24/n...

25.02.2026 17:19 👍 1 🔁 0 💬 1 📌 0
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25.02.2026 17:13 👍 0 🔁 0 💬 0 📌 0
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Leader of Columbia Brain Institute Quits Over Friendship With Epstein

Power lures people to abuse young girls no matter IQ, gender or nationality.

The Epstein files reveal - scientists are not immune.

Leader of Columbia Brain Institute Quits Over Friendship With Epstein www.nytimes.com/2026/02/25/n...

25.02.2026 16:22 👍 7 🔁 3 💬 1 📌 0

and studies from the Philippines election of Bong Bong Marcos shows repeating a lie ad nauseum is effective. He was elected despite his fathers record breaking kleptocracy - because theFace Book algorithm amplified his lies about his mother being innocent of corruption. He repeated this for years.

24.02.2026 23:24 👍 0 🔁 0 💬 0 📌 0