Zhaoshan Zhong

After 5 years of sample collection and analysis our paper examining the impacts of an industrial #DeepSea mining trial on seafloor #biodiversity is published! Read here: www.nature.com/articles/s41...

A deep-sea hydrothermal vent worm detoxifies arsenic and sulfur by intracellular biomineralization of orpiment (As2S3) The deep-sea worm Paralvinella hessleri thrives in extreme hydrothermal vents, tolerating high arsenic and hydrogen sulfide levels. This study shows that it detoxifies both by forming orpiment (As₂S₃)...

Checkout our latest article about fighting poison with poison found at PLOS: dx.plos.org/10.1371/jour...

Not-so-mutually beneficial coral symbiosis The partnership between corals and their intracellular algal symbionts has long been a textbook example of mutually beneficial association. In this essay, Mikhail Matz argues for an updated view in which the coral acts more as a farmer of algal cells to support its own growth.

I missed this when it came out last September - excellent essay!
Not-so-mutually beneficial coral symbiosis: Current Biology www.cell.com/current-biol...

Mystery of billions of sea-star deaths solved at last Experiments identify a bacterium as the cause of sea-star wasting disease, which has devastated populations along the western coast of North America.

Scientists have finally pinpointed the cause of a marine die-off of unprecedented scale

go.nature.com/4mvYGmd

Flourishing chemosynthetic life at the greatest depths of hadal trenches - Nature The discovery of chemosynthesis-based benthic communities at depths of 5,800 m to 9,533 m in the Kuril–Kamchatka and western Aleutian trenches challenges traditional perspectives on the energy sources sustaining hadal fauna.

Nature research paper: Flourishing chemosynthetic life at the greatest depths of hadal trenches

go.nature.com/3H1Dg1f

Whole-genome sequencing of 490,640 UK Biobank participants - Nature A study reports whole-genome sequences for 490,640 participants from the UK Biobank and combines these data with phenotypic data to provide new insights into the relationship between human variation and sequence variation.

Nature research paper: Whole-genome sequencing of 490,640 UK Biobank participants

go.nature.com/46EtTyW

Lithium deficiency and the onset of Alzheimer’s disease - Nature Lithium has an essential role in the brain and is deficient early in Alzheimer’s disease, which can be recapitulated in mice and treated with a novel lithium salt that restores the physiological level.

Nature research paper: Lithium deficiency and the onset of Alzheimer’s disease

go.nature.com/4ftdsb2

The role of holobiont composition and environmental history in thermotolerance of Tropical Eastern Pacific corals #coral #holobiont #symbionts www.sciencedirect.com/science/arti...

Programmable control of spatial transcriptome in live cells and neurons - Nature CRISPR-TO, a system for programmable control of spatial localization of cellular RNAs, is presented and enables functional investigation of endogenous RNA localization in diverse living cells.

Nature research paper: Programmable control of spatial transcriptome in live cells and neurons

https://go.nature.com/4mtCWbq

Multiple-omics analyses of the Alviniconcha holobiont reveal multi-faceted adaptations to deep-sea hydrothermal vents Deep-sea hydrothermal vents are ‘extreme’ environments with constantly fluctuating physicochemical conditions – but dense animal aggregations thrive primarily through symbiosis with chemoautotrophic b...

Multiple-omics analyses of the Alviniconcha #holobiont reveal multi-faceted adaptations to deep-sea hydrothermal vents

www.biorxiv.org/content/10.1...

These are the most-cited research papers of all time Some studies have received hundreds of thousands of citations, Nature’s updated analysis shows.

What are the most-cited research papers of all time?

https://go.nature.com/3Y4OMOD

Spatial multi-omics reveals cell-type-specific nuclear compartments - Nature A genomic barcoding scheme called two-layer DNA seqFISH+ enables the simultaneous mapping of more than 100,000 loci and has been used to identify cell-type-specific subnuclear compartments in the mouse brain.

Nature research paper: Spatial multi-omics reveals cell-type-specific nuclear compartments

https://go.nature.com/4jngJJB

火星取样返回任务（天问三号） 国际合作机遇公告 火星取样返回任务（天问三号）国际合作机遇公告.pdf

China has announced international cooperation for Mars Sample Return Mission (Tianwen-3). Launch planned ~2028 (!) Samples return to Earth ~2030. Objectives: Life detection, Mars geology, atmosphere studies. www.cnsa.gov.cn/n6758823/n67...

So beautiful work for HGT in insect symbioses

Genomic divergence across the tree of life | PNAS Nucleotide sequence data are being harnessed to identify species, even in cases in which organisms themselves are neither in hand nor witnessed. Bu...

Genomic divergence across the tree of life | PNAS www.pnas.org/doi/full/10....

Sequencing-based analysis of microbiomes - Nature Reviews Genetics In this Review, Pinto and Bhatt provide an overview of DNA-sequencing and RNA-sequencing approaches that can be used to study the composition, structure, and function of microbiomes and discuss the bi...

1/ Our review on sequencing-based #microbiome analysis is in the Dec 24 issue of Nature Reviews Genetics. We explore DNA/RNA-sequencing approaches for studying microbiome structure and function, highlighting the biological insights sequencing-based microbiome research offers.
go.nature.com/3XFqonu

Amazing

Here is the mollusc tree. (We fixed it, you're welcome.) 😇 @sgn.one @oceanspecies.bsky.social @kmkocot.bsky.social
@squamiferum.bsky.social www.science.org/doi/10.1126/...

Revealing how fungi build planet-altering ‘road’ networks Nature - Imaging study reveals how fungal networks are constructed.

Fungi made Earth’s land liveable by building networks that released nutrients locked in primordial rock and supplied those nutrients to plant roots

https://go.nature.com/3QLda3z

Check out the latest issue of The Innovation Geoscience!!!
Volume 3, Issue 1 is now online!
www.the-innovation.org/geoscience/a...
#Geoscience #research #ClimateCrisis #pollution #carbon #emissions #remotesensing #Satelite #paleoclimate #monsoon #drought

So wild

Beautiful! Where are the deep-sea mussels from and what is the species living in the mussel bed?

A deep ocean cold seep community with mussels, tube worms, shrimp, purple, sea cucumber, squat lobster, and white sea anemone.

Cold seep community painting- I was thinking this would make a nice back cover for the book. My fav is the anemone because it’s so dramatic and was fun to paint. 16x20 acrylic on canvas
#SciArt #deepsea #deepseacreatures #coldseep #acrylicpainting

EasyMetagenome: A user‐friendly and flexible pipeline for shotgun metagenomic analysis in microbiome research EasyMetagenome is a user-friendly shotgun metagenomics pipeline designed for comprehensive microbiome analysis, supporting quality control, host removal, read-based, assembly-based, binning, genome a....

onlinelibrary.wiley.com/doi/full/10....

Protein codes promote selective subcellular compartmentalization Cells have evolved mechanisms to distribute ~10 billion protein molecules to subcellular compartments where diverse proteins involved in shared functions must assemble. Here, we demonstrate that prote...

Protein codes promote selective subcellular compartmentalization | Science www.science.org/doi/10.1126/...

Genetic and geographical origins of Eurasia’s influential Yamna culture Ancient genomes from Ukraine and Russia reveal Yamna origins.

Ancient genomes from modern Ukraine and Russia reveal the origins of the Yamna people, pastoralists who migrated from the Eurasian steppe to Europe 5,000 years ago, spreading their ancestry, culture and, probably, language

https://go.nature.com/3Q9klm2

Climate change in the polar regions of our warming world is threatening to transform many of its features, such as this icy tableau in the Fish Islands off the coast of the Antarctic Peninsula. There is still much to learn about these places before we know better what those changes may be.

A new special issue of Science highlights research on Earth’s frozen places—from the Arctic to the Antarctic—and how it’s changing due to climate change and the geopolitical challenges this important work faces.

Learn more: https://scim.ag/4jPYRID

Wild frontiers of model organisms

Wild frontiers of model organisms www.embl.org/about/info/c...

Excited about this brand new EMBO | EMBL Symposium on understanding the biology, ecology and evolution of non-model organisms, ranging from microbes to plants and animals

📅 8 – 11 April 2025
📜 Submit your abstract by 14 January!

Interesting to note that many of these adaptations come with the loss of the arbuscular mycorrhizal symbiosis. In a way these lineages have rediced their ability to deal with the surrounding iotic environment (or evolved alternative ways to do so).

Simulating 500 million years of evolution with a language model More than three billion years of evolution have produced an image of biology encoded into the space of natural proteins. Here we show that language models trained at scale on evolutionary data can gen...

Whoa! When a large language of life model generates a protein equivalent to ~500 million years of evolution.
@science.org
science.org/doi/10.1126/...