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Stem Cell Evidence

@stemcellevidence

Curating the evidence in haematopoietic stem cell transplantation. Free monthly Stem Cell Evidence Alert http://bit.ly/2HMQtb5 @stemcellevidence@fediscience.org #MedSky

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20.11.2024
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Latest posts by Stem Cell Evidence @stemcellevidence

Preview
GVHD prophylaxis after cord blood transplantation in patients with high-risk AML: a nationwide Japanese cohort study Cord blood transplantation (CBT) is a curative option for patients with high-risk acute myeloid leukemia (AML), including therapy-related AML (t-AML). However, the optimal prophylaxis for graft-versus...

#StemCellEvidence link to:

GVHD prophylaxis after cord blood transplantation in patients with high-risk AML: a nationwide Japanese cohort study
by Yamasaki et al.
www.stemcellevidence.com/alerts/artic...
#MedSky

09.03.2026 18:41 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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GVHD prophylaxis after cord blood transplantation in patients with high-risk AML: a nationwide Japanese cohort study 
by Yamasaki et al.

featured in the Stem Cell Evidence Alert - February 2026

Image showing a PICO summary for: GVHD prophylaxis after cord blood transplantation in patients with high-risk AML: a nationwide Japanese cohort study by Yamasaki et al. featured in the Stem Cell Evidence Alert - February 2026

New from the #StemCellEvidence Alert:

GVHD prophylaxis after cord blood transplantation in patients with high-risk AML: a nationwide Japanese cohort study
by Yamasaki et al.
#MedSky

09.03.2026 18:40 πŸ‘ 1 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0
Preview
Efficacy and safety of ruxolitinib for graft-versus-host disease prophylaxis in allogeneic hematopoietic stem cell transplantation: a systematic review and meta-analysis INTRODUCTION: Graft-versus-host disease (GVHD) remains a major complication after allogeneic hematopoietic stem cell transplantation (allo-HSCT). Despite standard prophylaxis, acute and chronic GVHD i...

#StemCellEvidence link to:

Efficacy and safety of ruxolitinib for graft-versus-host disease prophylaxis in allogeneic hematopoietic stem cell transplantation: a #systematicreview and #metaanalysis
by Xie e al.
www.stemcellevidence.com/alerts/artic...
#MedSky

06.03.2026 10:24 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Efficacy and safety of ruxolitinib for graft-versus-host disease prophylaxis in allogeneic hematopoietic stem cell transplantation: a #systematicreview and #metaanalysis 
by Xie e al.
featured in the Stem Cell Evidence Alert - February 2026

Image showing a PICO summary for: Efficacy and safety of ruxolitinib for graft-versus-host disease prophylaxis in allogeneic hematopoietic stem cell transplantation: a #systematicreview and #metaanalysis by Xie e al. featured in the Stem Cell Evidence Alert - February 2026

From the #StemCellEvidence Alert:

Efficacy and safety of ruxolitinib for graft-versus-host disease prophylaxis in allogeneic hematopoietic stem cell transplantation: a #systematicreview and #metaanalysis
by Xie e al.
#MedSky

06.03.2026 10:24 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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Effects of rhEPO-Fc on chronic renal anemia in Chinese patients undergoing maintenance hemodialysis: a multicenter, randomized, open-label, and phase 3 study by Gan et al.
Featured in the Transfusion Evidence Alert – February 2026

Image showing a PICO summary for: Effects of rhEPO-Fc on chronic renal anemia in Chinese patients undergoing maintenance hemodialysis: a multicenter, randomized, open-label, and phase 3 study by Gan et al. Featured in the Transfusion Evidence Alert – February 2026

From the #Transfusion Evidence Alert:

Effects of rhEPO-Fc on chronic renal anemia in Chinese patients undergoing maintenance hemodialysis: a multicenter, randomized, open-label, and phase 3 study
by Gan et al.

Transfusion Evidence Library link in replies
#MedSky

06.03.2026 10:11 πŸ‘ 0 πŸ” 2 πŸ’¬ 1 πŸ“Œ 0
Preview
Real-world outcomes of tisagenlecleucel treatment in patients with relapsed or refractory large B-cell lymphomas: a nationwide registry BACKGROUND: Chimeric antigen receptor (CAR) T-cell therapy has transformed treatment for patients with relapsed or refractory large B-cell lymphoma (LBCL). However, real-world data in Japan remain lim...

#StemCellEvidence link to:

Real-world outcomes of tisagenlecleucel treatment in patients with relapsed or refractory large B-cell lymphomas: a nationwide registry
by Sakurai et al.
www.stemcellevidence.com/alerts/artic...
#MedSky

05.03.2026 12:34 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Image showing a PICO summary for:

Real-world outcomes of tisagenlecleucel treatment in patients with relapsed or refractory large B-cell lymphomas: a nationwide registry 
by Sakurai et al.
featured in the Stem Cell Evidence Alert - February 2026

Image showing a PICO summary for: Real-world outcomes of tisagenlecleucel treatment in patients with relapsed or refractory large B-cell lymphomas: a nationwide registry by Sakurai et al. featured in the Stem Cell Evidence Alert - February 2026

New from the #StemCellEvidence Alert:

Real-world outcomes of tisagenlecleucel treatment in patients with relapsed or refractory large B-cell lymphomas: a nationwide registry
by Sakurai et al.
#MedSky

05.03.2026 12:33 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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Study of Centrifugal Therapeutic Plasma Exchange and Membrane Therapeutic Plasma Exchange; A Comparative Study by Elghoneimy et al.
Featured in the Transfusion Evidence Alert – February 2026

Image showing a PICO summary for: Study of Centrifugal Therapeutic Plasma Exchange and Membrane Therapeutic Plasma Exchange; A Comparative Study by Elghoneimy et al. Featured in the Transfusion Evidence Alert – February 2026

New from the #Transfusion Evidence Alert:

Study of Centrifugal Therapeutic Plasma Exchange and Membrane Therapeutic Plasma Exchange; A Comparative Study
by Elghoneimy et al.

Transfusion Evidence Library link in replies
#MedSky

05.03.2026 11:31 πŸ‘ 0 πŸ” 2 πŸ’¬ 1 πŸ“Œ 0
Image showing a PICO summary for:
Efficacy of Desmopressin for Post-Kidney Biopsy Bleeding Complications Prevention: A Systematic Review With Frequentist and Bayesian Meta-Analysis by Chen et al.
Featured in the Transfusion Evidence Alert – February 2026

Image showing a PICO summary for: Efficacy of Desmopressin for Post-Kidney Biopsy Bleeding Complications Prevention: A Systematic Review With Frequentist and Bayesian Meta-Analysis by Chen et al. Featured in the Transfusion Evidence Alert – February 2026

From the #Transfusion Evidence Alert:

Efficacy of Desmopressin for Post-Kidney Biopsy Bleeding Complications Prevention: A Systematic Review With Frequentist and Bayesian Meta-Analysis
by Chen et al.

Transfusion Evidence Library link in the comments
#MedSky

04.03.2026 09:54 πŸ‘ 0 πŸ” 2 πŸ’¬ 1 πŸ“Œ 0
Preview
Modeling donor age and type trade-offs for personalized selection in allogeneic hematopoietic cell transplantation with post-transplant cyclophosphamide prophylaxis The prevailing fixed-hierarchy approach to donor selection for allogeneic hematopoietic cell transplantation (HCT) fails to capture critical interactions between donor age and type. We addressed this ...

#StemCellEvidence link to:

Modeling donor age and type trade-offs for personalized selection in allogeneic hematopoietic cell transplantation with post-transplant cyclophosphamide prophylaxis
by Mehta et al.
www.stemcellevidence.com/alerts/artic...
#MedSky

04.03.2026 07:51 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Image showing a PICO summary for:

Modeling donor age and type trade-offs for personalized selection in allogeneic hematopoietic cell transplantation with post-transplant cyclophosphamide prophylaxis 
by Mehta et al.
featured in the Stem Cell Evidence Alert - February 2026

Image showing a PICO summary for: Modeling donor age and type trade-offs for personalized selection in allogeneic hematopoietic cell transplantation with post-transplant cyclophosphamide prophylaxis by Mehta et al. featured in the Stem Cell Evidence Alert - February 2026

From the #StemCellEvidence Alert:

Modeling donor age and type trade-offs for personalized selection in allogeneic hematopoietic cell transplantation with post-transplant cyclophosphamide prophylaxis
by Mehta et al.
#MedSky

04.03.2026 07:50 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
Image showing a PICO summary for:

Intravenous iron for non-anaemic iron deficiency in pregnancy: a multicentre, two-arm, randomised controlled trial 
by Wasim et al.
featured in the Transfusion Evidence Alert - February 2026

Image showing a PICO summary for: Intravenous iron for non-anaemic iron deficiency in pregnancy: a multicentre, two-arm, randomised controlled trial by Wasim et al. featured in the Transfusion Evidence Alert - February 2026

New from the #Transfusion Evidence Alert:

Intravenous iron for non-anaemic iron deficiency in pregnancy: a multicentre, two-arm, randomised controlled trial
by Wasim et al.
#MedSky

03.03.2026 13:04 πŸ‘ 2 πŸ” 2 πŸ’¬ 1 πŸ“Œ 0
Preview
Re-Evaluating Donor Selection Priorities for Hematopoietic Cell Transplantation With Post-Transplant Cyclophosphamide PURPOSE: The prognostic significance of traditional donor selection criteria for human leukocyte antigen (HLA)-matched unrelated donor (MUD) hematopoietic cell transplantation (HCT) is uncertain in th...

Stem Cell Evidence link to:
Re-Evaluating Donor Selection Priorities for Hematopoietic Cell Transplantation With Post-Transplant Cyclophosphamide
by Mehta et al.
www.stemcellevidence.com/alerts/artic...

03.03.2026 07:48 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Image showing a PICO summary for:
Re-Evaluating Donor Selection Priorities for Hematopoietic Cell Transplantation With Post-Transplant Cyclophosphamide 
by Mehta et al.
featured in the Stem Cell Evidence Alert - February 2026

Image showing a PICO summary for: Re-Evaluating Donor Selection Priorities for Hematopoietic Cell Transplantation With Post-Transplant Cyclophosphamide by Mehta et al. featured in the Stem Cell Evidence Alert - February 2026

New from the #StemCellEvidence Alert:

Re-Evaluating Donor Selection Priorities for Hematopoietic Cell Transplantation With Post-Transplant Cyclophosphamide
by Mehta et al.

#MedSky

03.03.2026 07:48 πŸ‘ 2 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0
Image showing an extract of the Transfusion Evidence Alert - February 2026

Image showing an extract of the Transfusion Evidence Alert - February 2026

The #Transfusion Evidence Alert is out!

Each month our clinical team picks the ten top references in the #transfusionmedicine field, each with a quick-format PICO summary, so you can rapidly identify what you need to read.
#MedSky

02.03.2026 10:37 πŸ‘ 2 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0
Image showing a PICO summary for:

Donor age and type in allogeneic haematopoietic stem cell transplantation: Strong effect in MDS, limited in AML 
by Kim et al.
featured in the Stem Cell Evidence Alert - February 2026

Image showing a PICO summary for: Donor age and type in allogeneic haematopoietic stem cell transplantation: Strong effect in MDS, limited in AML by Kim et al. featured in the Stem Cell Evidence Alert - February 2026

From the #StemCellEvidence Alert:

Donor age and type in allogeneic haematopoietic stem cell transplantation: Strong effect in MDS, limited in AML
by Kim et al.
www.stemcellevidence.com/alerts/artic...
#MedSky

02.03.2026 10:17 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
Image showing a PICO summary for:

Harnessing HLA Divergence for Improved Donor Selection in Haploidentical Haematopoietic Stem Cell Transplantation 
by Cordeiro et al.
featured in the Stem Cell Evidence Alert - February 2026

Image showing a PICO summary for: Harnessing HLA Divergence for Improved Donor Selection in Haploidentical Haematopoietic Stem Cell Transplantation by Cordeiro et al. featured in the Stem Cell Evidence Alert - February 2026

New from the #StemCellEvidence Alert:

Harnessing HLA Divergence for Improved Donor Selection in Haploidentical Haematopoietic Stem Cell Transplantation
by Cordeiro et al.
www.stemcellevidence.com/alerts/artic...
#MedSky

27.02.2026 08:59 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Image showing a PICO summary for:

How low can we go? Comparison of liberal and restrictive red cell transfusion thresholds in paediatric allogeneic haematopoietic stem cell transplantation: A randomized multicentre feasibility trial 
New et al.
featured in the Transfusion Evidence Round-Up- International Childhood Cancer Day 2026

Image showing a PICO summary for: How low can we go? Comparison of liberal and restrictive red cell transfusion thresholds in paediatric allogeneic haematopoietic stem cell transplantation: A randomized multicentre feasibility trial New et al. featured in the Transfusion Evidence Round-Up- International Childhood Cancer Day 2026

From the #Transfusion Evidence Round-Up- #InternationalChildhoodCancerDay 2026:
How low can we go? Comparison of liberal and restrictive red cell transfusion thresholds in paediatric (...)
New et al.
www.transfusionevidencelibrary.com/articles/402...
#MedSky
@isbt.bsky.social

27.02.2026 08:54 πŸ‘ 2 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
Image showing a PICO summary for:

RBC Alloimmunization Impacts Pediatric Sickle Cell Disease Transplant Outcomes and Transfusion Burden: A STAR Registry Report 
by Inam et al.
featured in the Stem Cell Evidence Alert - February 2026

Image showing a PICO summary for: RBC Alloimmunization Impacts Pediatric Sickle Cell Disease Transplant Outcomes and Transfusion Burden: A STAR Registry Report by Inam et al. featured in the Stem Cell Evidence Alert - February 2026

From the #StemCellEvidence Alert:

RBC Alloimmunization Impacts Pediatric Sickle Cell Disease Transplant Outcomes and Transfusion Burden: A STAR Registry Report
by Inam et al.
www.stemcellevidence.com/alerts/artic...
#MedSky

26.02.2026 14:16 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
Image showing a PICO summary for:

The impact of DNMT3A mutation on survival of AML patients receiving allotransplant in first remission depends on the karyotype and co-occurring mutations 
Abou Dalle et al.
featured in the Stem Cell Evidence Alert - February 2026

Image showing a PICO summary for: The impact of DNMT3A mutation on survival of AML patients receiving allotransplant in first remission depends on the karyotype and co-occurring mutations Abou Dalle et al. featured in the Stem Cell Evidence Alert - February 2026

New from the #StemCellEvidence Alert:

The impact of DNMT3A mutation on survival of AML patients receiving allotransplant in first remission depends on the karyotype and co-occurring mutations
by Abou Dalle et al.
www.stemcellevidence.com/alerts/artic...
#MedSky

25.02.2026 09:46 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Image showing a PICO summary for:

Orca-T versus allogeneic hematopoietic stem cell transplantation (PRECISION-T): a multicenter, randomized phase 3 trial 
by Meyer et al.
featured in the Stem Cell Evidence Alert - February 2026

Image showing a PICO summary for: Orca-T versus allogeneic hematopoietic stem cell transplantation (PRECISION-T): a multicenter, randomized phase 3 trial by Meyer et al. featured in the Stem Cell Evidence Alert - February 2026

From the #StemCellEvidence Alert:

Orca-T versus allogeneic hematopoietic stem cell transplantation (PRECISION-T): a multicenter, randomized phase 3 trial
by Meyer et al.
www.stemcellevidence.com/alerts/artic...

24.02.2026 10:40 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
Image showing a PICO summary for: 

Hematopoietic Stem Cell Transplantation Outcomes for High-Risk AML: A Report From the Children's Oncology Group 
by Huang et al.
featured in the Transfusion Evidence Round-Up: International Childhood Cancer Day 2026

Image showing a PICO summary for: Hematopoietic Stem Cell Transplantation Outcomes for High-Risk AML: A Report From the Children's Oncology Group by Huang et al. featured in the Transfusion Evidence Round-Up: International Childhood Cancer Day 2026

From the #Transfusion Evidence Round-Up- #InternationalChildhoodCancerDay 2026:

Hematopoietic Stem Cell Transplantation Outcomes for High-Risk AML: A Report From the Children's Oncology Group
by Huang et al.
www.stemcellevidence.com/articles/402...
#MedSky
@isbt.bsky.social

24.02.2026 10:24 πŸ‘ 2 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
Image showing an extract of the Stem Cell Evidence Alert - February 2026

Image showing an extract of the Stem Cell Evidence Alert - February 2026

The #StemCellEvidence monthly alert is out!

See the top 10 articles, read the PICO summaries, and subscribe to this alert here:
www.stemcellevidence.com/alerts/latest
#MedSky

23.02.2026 12:54 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
Image showing a PICO summary for:

Impact of donor selection in adverse-risk AML undergoing hematopoietic cell transplantation: A study from the EBMT Acute Leukemia Working Party 
by Villalba et al.
featured in the Stem Cell Evidence Alert - January 2026

Image showing a PICO summary for: Impact of donor selection in adverse-risk AML undergoing hematopoietic cell transplantation: A study from the EBMT Acute Leukemia Working Party by Villalba et al. featured in the Stem Cell Evidence Alert - January 2026

From the #StemCellEvidence Alert:

Impact of donor selection in adverse-risk AML undergoing hematopoietic cell transplantation: A study from the EBMT Acute Leukemia Working Party
by Villalba et al.
www.stemcellevidence.com/alerts/artic...
#MedSky

18.02.2026 07:19 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Image showing a banner about the Talking Transfusion Podcast - International Childhood Cancer Day 2026

Image showing a banner about the Talking Transfusion Podcast - International Childhood Cancer Day 2026

The #Transfusion Evidence Round-Up: #InternationalChildhoodCancerDay 2026 is out!

πŸ“„See the top articles:
www.transfusionevidencelibrary.com/alerts/latest
www.stemcellevidence.com/articles/sea...
πŸŽ™οΈand listen to the podcast here:
open.spotify.com/episode/4T6v...
#MedSky
@isbt.bsky.social

17.02.2026 11:39 πŸ‘ 2 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
Image showing a PICO summary for:

Comparison of Myeloablative Busulfan/Cyclophosphamide and Busulfan/Fludarabine for Allogeneic Hematopoietic Stem Cell Transplantation: A #SystematicReview and #Meta-Analysis 
by Shimada et al.
featured in the Stem Cell Evidence Alert - January 2026

Image showing a PICO summary for: Comparison of Myeloablative Busulfan/Cyclophosphamide and Busulfan/Fludarabine for Allogeneic Hematopoietic Stem Cell Transplantation: A #SystematicReview and #Meta-Analysis by Shimada et al. featured in the Stem Cell Evidence Alert - January 2026

New from the #StemCellEvidence Alert:

Comparison of Myeloablative Busulfan/Cyclophosphamide and Busulfan/Fludarabine for Allogeneic Hematopoietic Stem Cell Transplantation: A #SystematicReview and #Meta-Analysis
by Shimada et al.
www.stemcellevidence.com/alerts/artic...
#MedSky

17.02.2026 10:49 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Image showing a PICO summary for:

Model-based antithymocyte globulin dosing in ex vivo CD34+ selected allogeneic haematopoietic cell transplantation: a single-centre, single-arm, phase 2 study 
by Scordo et al.
featured in the Stem Cell Evidence Alert - January 2026

Image showing a PICO summary for: Model-based antithymocyte globulin dosing in ex vivo CD34+ selected allogeneic haematopoietic cell transplantation: a single-centre, single-arm, phase 2 study by Scordo et al. featured in the Stem Cell Evidence Alert - January 2026

From the #StemCellEvidence Alert:

Model-based antithymocyte globulin dosing in ex vivo CD34+ selected allogeneic haematopoietic cell transplantation: a single-centre, single-arm, phase 2 study
by Scordo et al.
www.stemcellevidence.com/alerts/artic...
#MedSky

16.02.2026 07:28 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Image showing a PICO summary for:

Outcomes following matched sibling donor transplantation for severe combined immunodeficiency: a report from the PIDTC 
by Rayes et al.
featured in the Stem Cell Evidence Alert - January 2026

Image showing a PICO summary for: Outcomes following matched sibling donor transplantation for severe combined immunodeficiency: a report from the PIDTC by Rayes et al. featured in the Stem Cell Evidence Alert - January 2026

New from the #StemCellEvidence Alert:

Outcomes following matched sibling donor transplantation for severe combined immunodeficiency: a report from the PIDTC
by Rayes et al.
www.stemcellevidence.com/alerts/artic...
#MedSky

13.02.2026 07:45 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Image showing a PICO summary for:

Genetic Findings of Potential Donor Origin in Cells Used for Cell and Gene Therapy: Recommendations from the World Marrow Donor Association 
by Pryce et al.
featured in the Stem Cell Evidence Alert - January 2026

Image showing a PICO summary for: Genetic Findings of Potential Donor Origin in Cells Used for Cell and Gene Therapy: Recommendations from the World Marrow Donor Association by Pryce et al. featured in the Stem Cell Evidence Alert - January 2026

From the #StemCellEvidence Alert:

Genetic Findings of Potential Donor Origin in Cells Used for Cell and Gene Therapy: Recommendations from the World Marrow Donor Association
by Pryce et al.
www.stemcellevidence.com/alerts/artic...
#MedSky

12.02.2026 12:47 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
Image showing a PICO summary for:

Non-T-Depleted Haploidentical Transplantation Compared to Allogeneic Transplantation From Matched Siblings or Unrelated Donors in Patients With Secondary AML in First Complete Remission: A Study From the ALWP/EBMT 
by Nagler et al.
featured in the Stem Cell Evidence Alert - January 2026

Image showing a PICO summary for: Non-T-Depleted Haploidentical Transplantation Compared to Allogeneic Transplantation From Matched Siblings or Unrelated Donors in Patients With Secondary AML in First Complete Remission: A Study From the ALWP/EBMT by Nagler et al. featured in the Stem Cell Evidence Alert - January 2026

New from the #StemCellEvidence Alert:

Non-T-Depleted Haploidentical Transplantation Compared to Allogeneic Transplantation From Matched Siblings or Unrelated Donors in Patients With Secondary AML in First Complete Remission (...)
by Nagler et al.
www.stemcellevidence.com/alerts/artic...
#MedSky

11.02.2026 11:47 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0