Takehiro A. Ozawa's Avatar

Takehiro A. Ozawa

@tkozawa

PhD graduate at CINVESTAV Unidad Irapuato ๐Ÿ‡ฒ๐Ÿ‡ฝ. Interested in microalgae (e.g. Botryococcus braunii), algal biotechnology and plant energy management (i.e. #PlantTOR and #SnRK1 signaling pathways ๐ŸŒฑโšก๏ธ).

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08.11.2024
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Latest posts by Takehiro A. Ozawa @tkozawa

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โžก๏ธPlants donโ€™t manage nutrients one at a time.
Sulfur metabolism is tightly wired to nitrogen, phosphorus, and iron networks. Our new review explores the regulatory hubs (SLIM1, PHR1, NLP7, FIT) shaping this nutrient cross-talk in Arabidopsis. academic.oup.com/jxb/article/...

07.03.2026 12:49 ๐Ÿ‘ 10 ๐Ÿ” 1 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Fig. 1 (shortened, full legend in paper): Regulation of TOR function by chloroplast-derived metabolites. (A) Photosynthetically derived sugars exported from the chloroplast activate TOR (via phosphorylation, P) in distal plant tissues. Sugar regulation of TOR can occur via SnRK1, or potentially via other routes (dashed arrow). Notably, TOR activation by sugar in roots requires mitochondrial function. (B) DHAP, a triose phosphate product of photosynthesis, positively regulates TOR in the green alga Chlamydomonas. (C) Active TOR directly phosphorylates the ABA receptor PYL, thereby inhibiting it. ABA, whose precursors are made in the chloroplast, binds PYL. ABA-bound PYL binds and inhibits the PP2C phosphatase, activating SNRK2. Active SNRK2 directly phosphorylates the RAPTOR subunit of TOR, inhibiting TOR activity.

Fig. 1 (shortened, full legend in paper): Regulation of TOR function by chloroplast-derived metabolites. (A) Photosynthetically derived sugars exported from the chloroplast activate TOR (via phosphorylation, P) in distal plant tissues. Sugar regulation of TOR can occur via SnRK1, or potentially via other routes (dashed arrow). Notably, TOR activation by sugar in roots requires mitochondrial function. (B) DHAP, a triose phosphate product of photosynthesis, positively regulates TOR in the green alga Chlamydomonas. (C) Active TOR directly phosphorylates the ABA receptor PYL, thereby inhibiting it. ABA, whose precursors are made in the chloroplast, binds PYL. ABA-bound PYL binds and inhibits the PP2C phosphatase, activating SNRK2. Active SNRK2 directly phosphorylates the RAPTOR subunit of TOR, inhibiting TOR activity.

๐ŸŒฟ๐Ÿ” SPECIAL ISSUE REVIEW ๐Ÿ”๐ŸŒฟ

Crespo et al. examine the central role of the TOR kinase in linking nutrient availability to chloroplast function, detailing emerging evidence of reciprocal regulation between TOR signalling and photosynthesis in plants and algae ๐Ÿงช

๐Ÿ”— doi.org/10.1093/jxb/...

07.03.2026 12:00 ๐Ÿ‘ 23 ๐Ÿ” 7 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0
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Paging senior graduate students! Apply to present your research during the Salk Discover symposium and network with potential collaborators or faculty advisors. Application deadline extended to March 16.

More info: www.salk.edu/about/our-co...

06.03.2026 21:13 ๐Ÿ‘ 3 ๐Ÿ” 7 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

Congrats @ottlab.bsky.social and @pengbo10.bsky.social for leading this work!

06.03.2026 11:39 ๐Ÿ‘ 25 ๐Ÿ” 11 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 1
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An unconventional Rubisco small subunit underpins the CO2-concentrating organelle in land plants In many algae, photosynthesis is boosted by biophysical CO2-concentrating mechanisms, which pack the CO2-fixing enzyme Rubisco into liquid-like organelles called pyrenoids. Engineering C3 crops with a...

Our work on #hornwort #pyrenoids is finally out in @science.org! ๐ŸŽ‰ We uncovered how hornworts pack their Rubisco into pyrenoids and successfully recreated them in Arabidopsis. A key step toward engineering more efficient photosynthesis in crops @btiscience.bsky.social www.science.org/doi/10.1126/...

05.03.2026 20:03 ๐Ÿ‘ 124 ๐Ÿ” 63 ๐Ÿ’ฌ 6 ๐Ÿ“Œ 7

Excited to share our latest preprint. Arabidopsis thaliana has been the leading model for plant genetics - but most of what we know comes from growth chambers.
Can this model also help us understand how climate shapes plants in the wild and reveal gene functions under real environmental variability?

04.03.2026 20:17 ๐Ÿ‘ 39 ๐Ÿ” 21 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0
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Job opportunity!

Research Assistant / Research Associate

An opportunity to join our team working on the generation of a completely engineered chloroplast genome (= synplastome).

Apply by Thursday 02 April 2026: www.jobs.cam.ac.uk/job/54695/

04.03.2026 09:13 ๐Ÿ‘ 7 ๐Ÿ” 7 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 1
Spatial distribution of isoprenoid enzymes and MpABCG1 transporter influences sesquiterpene accumulation in Marchantia polymorpha oil bodies - Communications Biology A study maps terpene biosynthesis in Marchantia polymorpha oil bodies and identifies the ABC transporter MpABCG1 as a key factor for endogenous sesquiterpene accumulation in oil bodies, informing futu...

New paper from the lab. Important insights into the compartmentalisation of terpene biosynthesis in Marchantia oil body cells. #PlantScience #SynBio www.nature.com/articles/s42...

04.03.2026 11:46 ๐Ÿ‘ 19 ๐Ÿ” 13 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

1/ โœจ New preprint alert โœจ

It is my pleasure to share:
"Stepwise evolution of the developmental and symbiotic functions of DELLA in land plants"

Here we investigated the role of the single GRAS transcription factor DELLA in #MyMarchantia

doi.org/10.64898/202...

#PlantScience
A thread...

04.03.2026 05:20 ๐Ÿ‘ 48 ๐Ÿ” 36 ๐Ÿ’ฌ 5 ๐Ÿ“Œ 2
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Postdoctoral Researcher - Evolutionary Genomics and Population Genetics Position Title: Postdoctoral Researcher - Evolutionary Genomics and Population Genetics Appointment Type: Post Doc/Trainee Job Description: Summary of Duties and Responsibilities: We are seeking a Pos...

Corrinne Grover and I are hiring a postdoc to work on population and comparative genomics in multiple crop species. Applications will be accepted through March 17th and details can be found here: isu.wd1.myworkdayjobs.com/IowaStateJob...

03.03.2026 17:54 ๐Ÿ‘ 3 ๐Ÿ” 5 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
The cover of Vol 77 | Issue 5 | 2026 of the Journal of Experimental Botany, Special Issue: Energy Management: Molecular Mechanisms and Signaling. Yellow coloured banners border the top and bottom of the page and in the centre the image depicts a whiteboard illustration of the original concept behind the workshop โ€˜Plant Energy Management: Molecular Mechanisms and Signalling,โ€™ held at UPSC, Sweden, in August 2024. The aim was to expand upon the original TOR meeting by focusing on the inputs and outputs of the core energy management machinery in a species-agnostic manner. (Credit: Benoรฎt Menand, Johannes Hanson, and Vanessa Wahl.)

The cover of Vol 77 | Issue 5 | 2026 of the Journal of Experimental Botany, Special Issue: Energy Management: Molecular Mechanisms and Signaling. Yellow coloured banners border the top and bottom of the page and in the centre the image depicts a whiteboard illustration of the original concept behind the workshop โ€˜Plant Energy Management: Molecular Mechanisms and Signalling,โ€™ held at UPSC, Sweden, in August 2024. The aim was to expand upon the original TOR meeting by focusing on the inputs and outputs of the core energy management machinery in a species-agnostic manner. (Credit: Benoรฎt Menand, Johannes Hanson, and Vanessa Wahl.)

๐Ÿ“ฃ Check out JXB's newest Special Issue ๐Ÿ“ฃ
๐Ÿ“˜ Issue 5 of 2026 ๐Ÿ“˜

โšก๐ŸŒฟ Energy Management: Molecular Mechanisms and Signalling ๐ŸŒฟโšก

๐Ÿ“˜ Guest edited by Benoรฎt Menand, Johannes Hanson & Vanessa Wahl

๐Ÿ”— academic.oup.com/jxb...

#JXBspecialissues #PlantScience ๐Ÿงช SEBiology

03.03.2026 13:35 ๐Ÿ‘ 16 ๐Ÿ” 5 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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High-frequency biparental inheritance of plant mitochondria upon chilling stress and loss of a genome-degrading nuclease - Nature Plants Maternal inheritance of mitochondria breaks down in the cold when a mitochondrial DNA degrading nuclease is defective, resulting in biparental inheritance that can rescue mitochondrial mutations and g...

๐ŸŒฟ๐ŸงฌOur new story is out in @natplants.nature.com! Tobacco plants usually pass down their mitochondria maternally, but we show we can trigger paternal transmission of mitochondria at high levels & restore plant health in the offspring of mothers harboring defective mtDNA www.nature.com/articles/s41...

03.03.2026 11:24 ๐Ÿ‘ 17 ๐Ÿ” 10 ๐Ÿ’ฌ 3 ๐Ÿ“Œ 1

We are very excited to share a new resource from our team: spatial subcellular proteome maps in plants! We developed an MS-based method that registers localizations of about 8000 proteins in Arabidopsis roots in a single experiment.

(1/9)
www.biorxiv.org/cgi/content/...

03.03.2026 06:53 ๐Ÿ‘ 111 ๐Ÿ” 68 ๐Ÿ’ฌ 2 ๐Ÿ“Œ 1
Fig. 1. The core energy management machinery, comprising SnRKs, TORC, and the T6P pathway, and its interactions with multiple signals through complex feedback regulation to regulate growth and resilience trade-offs.

Fig. 1. The core energy management machinery, comprising SnRKs, TORC, and the T6P pathway, and its interactions with multiple signals through complex feedback regulation to regulate growth and resilience trade-offs.

The cover depicts a whiteboard illustration of the original concept behind the workshop โ€˜Plant Energy Management: Molecular Mechanisms and Signalling,โ€™ held at UPSC, Sweden, in August 2024. The aim was to expand upon the original TOR meeting by focusing on the inputs and outputs of the core energy management machinery in a species-agnostic manner. (Credit: Benoรฎt Menand, Johannes Hanson, and Vanessa Wahl.)

Link: https://academic.oup.com/jxb/issue/77/5

The cover depicts a whiteboard illustration of the original concept behind the workshop โ€˜Plant Energy Management: Molecular Mechanisms and Signalling,โ€™ held at UPSC, Sweden, in August 2024. The aim was to expand upon the original TOR meeting by focusing on the inputs and outputs of the core energy management machinery in a species-agnostic manner. (Credit: Benoรฎt Menand, Johannes Hanson, and Vanessa Wahl.) Link: https://academic.oup.com/jxb/issue/77/5

Summary of the special issue on #PlantTOR, #SnRK1 and #T6P that was edited by Wahl, Hanson and Menand (2026). ๐ŸŒฑโšก
"The plant energy management machinery: an essential hub for stress resilience and developmental dynamics with great potential for crop improvement"
๐Ÿ”— academic.oup.com/jxb/article/...

02.03.2026 19:11 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Photorespiration is linked to DNA methylation by formate as a one-carbon source - Nature Plants This study reveals that Arabidopsis reassimilates formate produced during photorespiration via the cytosolic folate cycle to fuel DNA methylation, forming a metabolicโ€“epigenetic bridge that links elev...

Delighted to share our paper, out today in @natplants.nature.com

Not all โ€œwastedโ€ carbon is lost: formate released during photorespiration can be reused to support DNA methylation. Our work reveals a metabolic link between COโ‚‚ levels and epigenetic regulation in Arabidopsis.
doi.org/10.1038/s414...

25.02.2026 11:38 ๐Ÿ‘ 26 ๐Ÿ” 7 ๐Ÿ’ฌ 2 ๐Ÿ“Œ 3
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Faculty position in Plant Molecular Biology (Associate Professor or Tenure-Track Assistant Professor) at Aarhus University, Denmark
mbg.au.dk/aktuelt/ledi...

25.02.2026 09:35 ๐Ÿ‘ 35 ๐Ÿ” 52 ๐Ÿ’ฌ 2 ๐Ÿ“Œ 1
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Postdoctoral Researcher - VIB We are looking for a highly motivated and talented postdoctoral researcher to join our team at the VIB-UGent Center for Plant Systems Biology. The selected candidate will join the Nelissen lab to deve...

The group of @hildenelissen.bsky.social is looking for a postdoctoral researcher to develop multiplex genome editing systems in sorghum, tropical maize and rice, leading to the identification of gene combinations strengthening seedling vigor. Please spread the news!
jobs.vib.be/j/129009/pos...

27.02.2026 09:53 ๐Ÿ‘ 4 ๐Ÿ” 8 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Immune activation suppresses reproductive growth in Arabidopsis through cytokinin signaling Johnston et al. report that defense hormones suppress cytokinin signaling, causing yield penalties. Restoring cytokinin in autoimmune plants relieves reproductive defects, confers broad pathogen resis...

Our beautiful work is out in Current Biology! @currentbiology.bsky.social

Immune activation suppresses reproductive growth in Arabidopsis through cytokinin signaling: Current Biology www.cell.com/current-biol...

27.02.2026 16:48 ๐Ÿ‘ 29 ๐Ÿ” 11 ๐Ÿ’ฌ 3 ๐Ÿ“Œ 0
CO2-concentrating mechanism model of inorganic carbon fluxes in Fragilariopsis cylindrus with or without external carbonic anhydrase at pHโ€‰8.1. T

CO2-concentrating mechanism model of inorganic carbon fluxes in Fragilariopsis cylindrus with or without external carbonic anhydrase at pHโ€‰8.1. T

Role of extracellular carbonic anhydrase in the polar diatom Fragilariopsis cylindrus

Li and Young

nph.onlinelibrary.wiley.com/doi/10.1111/...

27.02.2026 10:27 ๐Ÿ‘ 1 ๐Ÿ” 1 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Rewiring an E3 ligase enhances cold resilience and phosphate use in maize - Nature The E3 ubiquitin ligase NLA postively regulates cold tolerance and negatively regulates phosphate uptake in maize, and a genetically engineered variant of this enzyme leads to improved cold ...

@Nature: an E3 ligase, acting via the jasmonate pathway, is a common regulator of both cold stress & phosphate uptake. Guided by AI, the authors use genome editing to show the relevance of this finding for improving maize yield in multi-site field trials.
shorturl.at/KrKBo
& NV
shorturl.at/rwldu

25.02.2026 20:15 ๐Ÿ‘ 4 ๐Ÿ” 3 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Really happy to see this one out: www.sciencedirect.com/science/arti... Alibek's drive & great coll w/ friends @gekaragoz.bsky.social & E. Hallacli resulted in a cool story that starts with our beloved #Marchantia and ends with iPSC-derived neurons ๐Ÿคฉ๐Ÿคช A short ๐Ÿงต

23.02.2026 17:05 ๐Ÿ‘ 119 ๐Ÿ” 53 ๐Ÿ’ฌ 6 ๐Ÿ“Œ 7
Response to heat stress is mediated by reactive oxygen species accumulation that is enhanced in PtMCA-III triple KO mutants.

Response to heat stress is mediated by reactive oxygen species accumulation that is enhanced in PtMCA-III triple KO mutants.

Metacaspases contribute to the cellular response to heat stress in a marine diatom

Sadeh et al. @vardilab.bsky.social

nph.onlinelibrary.wiley.com/doi/10.1111/...

23.02.2026 15:35 ๐Ÿ‘ 2 ๐Ÿ” 4 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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I have a PhD student and a post-doc position available in my lab to work on plant photobiology. Please use the links below to postulate.
Please RT, many thanks
career5.successfactors.eu/career?caree...

career5.successfactors.eu/career?caree...

23.02.2026 13:18 ๐Ÿ‘ 33 ๐Ÿ” 61 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 3
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Together with many members of the broader community working on the fascinating Cyanidiophyceae (polyextremophilic ancient red algae), I'm happy to share our Tansley Review in @newphyt.bsky.social

nph.onlinelibrary.wiley.com/doi/10.1111/...

23.02.2026 06:25 ๐Ÿ‘ 7 ๐Ÿ” 5 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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The $100 whole human genome sequence finally reached!
www.sandiegouniontribune.com/2026/02/19/s...

20.02.2026 20:29 ๐Ÿ‘ 258 ๐Ÿ” 77 ๐Ÿ’ฌ 12 ๐Ÿ“Œ 11
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New Letter: "High-efficiency, transgene-free plant genome editing by viral delivery of an engineered TnpB" rdcu.be/e4XHZ

Viral vectors to deliver engineered smaller RNA-guided endonucleases eTnpBc, achieving high levels of somatic and heritable editing in plants.

20.02.2026 22:00 ๐Ÿ‘ 21 ๐Ÿ” 4 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0
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Delighted to share our new preprint: "Evolution of moss leaf-like organs through variations in deeply conserved developmental principles."
Led by Ph.D. student Wenye Lin from my lab @irbv.bsky.social ,
in collab. with Yoan Coudert (ENS Lyon) and Richard Smith (JIC).
www.biorxiv.org/content/10.6...

20.02.2026 12:40 ๐Ÿ‘ 66 ๐Ÿ” 35 ๐Ÿ’ฌ 3 ๐Ÿ“Œ 3
Life cycle of Cyanidiophyceae.

Life cycle of Cyanidiophyceae.

Fascinating single-cell red algae: models for evolution and adaptation

#TansleyReview by Berger et al.

nph.onlinelibrary.wiley.com/doi/10.1111/...

#plantscience

20.02.2026 02:45 ๐Ÿ‘ 14 ๐Ÿ” 7 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 1
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Harnessing microalgae for the biosynthesis of molecular crystals - Nature Biotechnology Crystalline materials for optical applications are synthesized in living dinoflagellates.

Harnessing microalgae for the biosynthesis of molecular crystals - @bengurionuniv.bsky.social go.nature.com/3MxVqui

19.02.2026 16:58 ๐Ÿ‘ 5 ๐Ÿ” 3 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0
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Ancient co-option of LTR retrotransposons as yeast centromeres - Nature Evolutionarily related โ€˜proto-pointโ€™ centromeres providing resolution to the evolutionary origins of point centromeres are identified in yeast, and comparison shows they evolved in an ancestor with re...

Our paper is now out in Nature:

โ€œAncient co-option of LTR retrotransposons as yeast centromeresโ€

www.nature.com/articles/s41...

A short thread on how retrotransposons helped give rise to yeast point centromeres.

1/14

18.02.2026 16:03 ๐Ÿ‘ 227 ๐Ÿ” 115 ๐Ÿ’ฌ 8 ๐Ÿ“Œ 10