Rhett Rautsaw

How does HiFi capture epigenetics in one run?

When a base is modified, its incorporation rate shifts. HiFi measures these kinetic signatures to detect 5mC and 6mA automatically with no extra library prep.

Watch our newest explainer video to see how: bit.ly/3YSPBdo

#TheresHiFiForThat #PacBio

Decoding cancer requires resolving transcript diversity within intact tissue.

Join our webinar to see how long-read sequencing and near-single-cell spatial transcriptomics reveal isoform diversity and map immune receptor clonotypes in tumors.

Register: bit.ly/4bsBanl

#PacBio #CancerResearch

One molecule. Multiple layers of biology.

HiFi sequencing = multiomic insights.

It reveals the genome, structural variants, full-length isoforms, and base-level methylation. All in one run. All from the same molecule.

Get the full picture: bit.ly/3YSPBdo

#PacBio #HiFisequencing #Multiomics

What happens when a condition shifts from rare to widespread?

In Episode 3 of Beyond the Bench, Dr. Birgitt Scheule explains what it means to shift from studying isolated cases to addressing disease at population scale.

Watch now: bit.ly/4oLrOXu

#BeyondTheBench #PacBio #HiFisequencing

Color the future of genomics at PRISM 2026.

Join us to see how HiFi sequencing evolves in real time. Meet our experts in person and hear research already influencing study design and results for large-scale studies.

Secure your place: bit.ly/4slZxZs

#PacBioPRISM #PacBio

Click the link and watch a short video to learn how HiFi sequencing works — brought to you by PacBio field support team

We've seen a big increase in the number of long-read #metagenomics publications, especially those using #PacBio HiFi data. Also very encouraging to all the new tools for long-read metagenome assembly & taxonomic profiling.

Complete list of publications: github.com/PacificBiosc...

HiFi sequencing can reveal rare and complex variants, but interpretation requires diverse background datasets.

PacBio and DNAstack are supporting the first global federated dataset of HiFi whole genomes through the HiFi Solves Global Consortium.

Details: bit.ly/4kQ0bMk

#WeCareForRare

💖 Feeling Solo this year?

Back by popular demand, Alex Dainis’ dating profile video shows how finding the right sequencing tech can feel like dating, with lots of mismatches before the perfect match.

See why HiFi on Vega is the perfect match + ask about out our new promos: bit.ly/3M6VmBi

Hi Molly! Reach out to Arima or Dovetail if you haven't already!

Thanks to everyone who joined our PacBio workshop today! 🌱🐄

We loved sharing how HiFi sequencing and SPRQ-Nx chemistry are advancing multiomic discoveries across genomes and populations. Stop by Booth #219 to continue the conversation!

#PAG33 #PacBio #PAG2026

The PacBio PAG 2026 party has begun! 🎉🌱🐄 We’re excited for a night of great conversation, connections, and celebrating the collaborations that make plant and animal genomics so inspiring.

#PAG33 #PacBio #PAG2026

Jeremy Schmutz at HudsonAlpha is the last talk of the @pacbio.bsky.social workshop at #PAG33 to talk about the cornucopia of genomics PacBio provides including beta testing results from SPRQ-Nx reusable SMRT Cells.

Christine Queitsch is up at @pacbio.bsky.social workshop at #PAG33 to talk about Fiber-Seq in Maize to look at chromatin accessibility, protein occupancy, and nucleosome positioning from a single HiFi experiment along with your long read sequencing data. @epicypher.bsky.social

Christine Queitsch walks us through Fiber-Seq in maize which is greatly increasing our understanding of the regulatory landscape of maize.

Brooke Peterson-Burch up next at @pacbio.bsky.social Workshop at #PAG33 to talk about gene prediction in crops using Kinnex Iso-Seq.

Shenia Sim at the USDA walks us through a single fruit fly’s journey to receiving a holistic genome using multiple applications on CiFi from a single SMRT cell.

#PacBio #PAG33 #PAG2026

Sheina Sim is up now @pacbio.bsky.social workshop at #PAG33 to talk about CiFi and multiomic holistic genomes in fruit flies.

See how Kendall Lee at HAIB and Veil Genomics is advancing Polyploid Genomics in blueberries using HiFi sequencing. A single Revio cell produces enough data for a high-quality assembly of a single blueberry, or low pass data on 12 individuals for population scale studies.

#PacBio #PAG33 #Revio

Kendall Lee from Veil Genomics is here! Time to learn about Long Read Low Pass sequencing along with some CiFi of Blueberries! 🫐 #PAG33 @pacbio.bsky.social

The room is filling up! If you’re not here you’re missing out on exciting updates on Kinnex Iso-Seq, Fiber-Seq chromatin accessibility, CiFi for HiFi based HiC scaffolding, and Low-Pass population sequencing. @pacbio.bsky.social @epicypher.bsky.social #PAG33

Jake is starting us off to tell us about the latest updates from @pacbio.bsky.social including SPRQ-Nx to drop costs with reusable SMRT Cells. #PAG33

PacBio workshop happening now at #PAG33. @pacbio.bsky.social. Come to learn more about multiomics and everything you can do with HiFi sequencing. #TheresHiFiForThat

Come join us!

Team Animal seems to be winning this round 🐱🌱!

Swing by Booth 219 at PAG 2026 to cast your vote in the ultimate Plant vs. Animal showdown, see live demonstrations of our Vega sequencing system, and meet the PacBio experts behind the science.

#PacBio #PAG33 #Vega #AnimalGenomics #PlantGenomics

Also don’t forget to register for the customer appreciation party!!

events.pacb.com/pag-2026-party

I’ll at #PAG33 with @pacbio.bsky.social. Don’t forget to stop by the booth or setup a meeting with us to talk about how PacBio HiFi sequencing can enhance your research!

bit.ly/4aLRhg4

Excited to share our final accepted version of the CiFi method out today: www.nature.com/articles/s41...

Countdown starts now.
The genomics series we’ve all been waiting for – a #PacBio original series.

Trailer’s out.
Premiere’s coming.

Add it to your watchlist 👇
🔗 bit.ly/4oLrOXu

Mabel and the Vega

Mabel and the Revio

Mabel and the Sequel

Annual Mabel with a Lego PacBio Sequencer. This time the Vega, but we also have the Revio and Sequel Lego edition.

World first: Radboudumc pioneers new genetic test in clinical practice - New test is faster, more efficient, and provides more diagnoses for rare diseases 17 November 2025

Long-read genome sequencing is new first-tier generic test in diagnostics of rare diseases

So satisfying to see a long journey end in best-possible diagnostic test for patients with rare diseases @radboudumc.bsky.social.

www.radboudumc.nl/en/news-item...

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