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Alain Kohl

@alainkohlvirology

Chair in Virology and Emerging Infectious Diseases, Liverpool School of Tropical Medicine. Arboviruses, emerging viruses, viruses of parasites!

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Latest posts by Alain Kohl @alainkohlvirology

We threw the kitchen sink and more at these viruses! ๐Ÿ”ฌ

Go check out the whole manuscript and discover some cool microscopy techniques applied on single viral particles!

07.03.2026 12:45 ๐Ÿ‘ 5 ๐Ÿ” 1 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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St. Lucia reports 1st chikungunya case in 5 years The Ministry of Health, Wellness and Nutrition informs the public of a confirmed case of Chikungunya virus (CHIKV) in Saint Lucia.

#StLucia reports 1st #chikungunya case in 5 years #Caribbean open.substack.com/pub/outbreak...

05.03.2026 22:45 ๐Ÿ‘ 1 ๐Ÿ” 1 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Bhattacharya urges measles vaccination as US activity increases

After remaining silent for almost a year about the U.S. measles outbreak, NIH/CDC poseur Jay Bhattacharya is now recommending measles vaccines.

And this is where he gets to see the impact of the destruction of trust in public health and vaccines, for which he is partially responsible.

04.03.2026 13:40 ๐Ÿ‘ 564 ๐Ÿ” 224 ๐Ÿ’ฌ 23 ๐Ÿ“Œ 15
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This man needed therapy, not a job running the US Military.

04.03.2026 13:24 ๐Ÿ‘ 692 ๐Ÿ” 155 ๐Ÿ’ฌ 99 ๐Ÿ“Œ 18
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โ€˜Truly spectacularโ€™ drug for sleeping sickness simplifies treatment, raising hopes for eradication European regulators greenlight new one-dose compound that could help African countries get rid of an ancient burden

European regulators have greenlit a new one-dose compound that could help African countries get rid of sleeping sickness. https://scim.ag/3MSxrG8

04.03.2026 14:30 ๐Ÿ‘ 52 ๐Ÿ” 18 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 1
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With Eugene Koonin, we propose a concept of โ€œthe selfish ribosomeโ€, under which evolution of life is viewed as a ribosomal takeover, where the ribosome evolved to consume most of the cellโ€™s resources, while other cellular componentry ensures the propagation of the ribosome. arxiv.org/abs/2602.23268

03.03.2026 08:58 ๐Ÿ‘ 223 ๐Ÿ” 96 ๐Ÿ’ฌ 5 ๐Ÿ“Œ 13

I have to agree. Slayers Reign in Blood equals it but Master of Puppets appealed to more people Iโ€™d think.

04.03.2026 14:29 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0

Why does it still take hours to submit a paper? Supposedly AI can replace us, maybe some journals can come up with something useful using AI where you just submit the front page and additional info and the info is extracted. Rather typing in author contributionsโ€ฆtotal waste of time.

27.02.2026 17:30 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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IMAV: International meeting on arboviruses and their vectors

Registration and abstract submission for the international Meeting on Arboviruses and their Vectors (a UK Microbiology Society event), Liverpool 1-2 September 2026, are now open!

Link:

microbiologysociety.org/event/full-e...

24.02.2026 13:00 ๐Ÿ‘ 4 ๐Ÿ” 6 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

The FIFA World Cup used to be the zenith of world football as an occasion. But the debased, corrupt & embarrassing rule of Gianni Infantino as head of FIFA has massively tarnished & diminished the World Cup.

22.02.2026 22:09 ๐Ÿ‘ 7 ๐Ÿ” 2 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 1
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Ancient co-option of LTR retrotransposons as yeast centromeres - Nature Evolutionarily related โ€˜proto-pointโ€™ centromeres providing resolution to the evolutionary origins of point centromeres are identified in yeast, and comparison shows they evolved in an ancestor with re...

Our paper is now out in Nature:

โ€œAncient co-option of LTR retrotransposons as yeast centromeresโ€

www.nature.com/articles/s41...

A short thread on how retrotransposons helped give rise to yeast point centromeres.

1/14

18.02.2026 16:03 ๐Ÿ‘ 227 ๐Ÿ” 115 ๐Ÿ’ฌ 8 ๐Ÿ“Œ 10
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New modelling suggests chikungunya transmission in Europe may be possible at lower temperatures than previously thoughtโ€”expanding the seasonal and geographic risk as the Asian tiger mosquito spreads north with warming climate.
: royalsocietypublishing.org/rsif/article...

18.02.2026 06:26 ๐Ÿ‘ 13 ๐Ÿ” 7 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0
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Could targeting viruses be a new hope against neurodegenerative diseases? Current therapies for neurodegenerative diseases largely manage symptoms and only modestly slow progression. This Perspective highlights emerging evidence that vaccines and antivirals may lowerโ€ฆ

Despite decades of intensive research, current approaches to treating #NeurodegenerativeDiseases only slow down the seemingly inevitable. Could recent data associating #vaccines with reduced risk of #dementia offer an unexpected beacon of hope?๐Ÿงช @sparrerlab.bsky.social

16.02.2026 14:05 ๐Ÿ‘ 12 ๐Ÿ” 7 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 1

It's important to put this in context of one of the first things Taubenberger did when he took over as the director of NIAID - he canceled the premier pandemic preparedness network ("CREID" - which we were part of) because it was deemed "unsafe for Americans".

Cc. @maxkozlov.bsky.social.

13.02.2026 21:36 ๐Ÿ‘ 49 ๐Ÿ” 22 ๐Ÿ’ฌ 5 ๐Ÿ“Œ 2
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A small polymerase ribozyme that can synthesize itself and its complementary strand The emergence of a chemical system capable of self-replication and evolution is a critical event in the origin of life. RNA polymerase ribozymes can replicate RNA, but their large size and structural ...

How could a simple self-replicating system emerge at the origins of life? RNA polymerase ribozymes can replicate RNA, but existing ones are so large that their self-replication seems impossible. Could they be smaller?

Excited to share our latest work in @science.org on a new small polymerase.
1/n

13.02.2026 11:42 ๐Ÿ‘ 497 ๐Ÿ” 209 ๐Ÿ’ฌ 10 ๐Ÿ“Œ 28

Seeing that Man U owner Ratcliffe claims the UK is being โ€œcolonisedโ€- how many Englishmen in their starting line up against West Ham? Shaw and Maguire?

12.02.2026 08:44 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

It shouldnโ€™t be a matter of talking about it. We all know this. And have for decades. Itโ€™s about restructuring careers.

11.02.2026 23:04 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

This is racist bating, anti-immigrant stuff from Jim Ratcliffe: a tax avoiding Monaco resident who gutted Manchester United FC (not to the extent of the Glazers) & presided over years of under-investment at Grangemouth oil refinery. Have we not had enough of being lectured by such folk?

11.02.2026 19:04 ๐Ÿ‘ 13 ๐Ÿ” 4 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

One of the maddest elements of Brexit - and there are *many* - is the rewards that continue to be lavished on the blithering idiots who sold it & continue to be proved wrong about everything every dayโ€ฆ

11.02.2026 08:34 ๐Ÿ‘ 2806 ๐Ÿ” 748 ๐Ÿ’ฌ 230 ๐Ÿ“Œ 25

Here we goโ€ฆ

06.02.2026 11:32 ๐Ÿ‘ 602 ๐Ÿ” 202 ๐Ÿ’ฌ 76 ๐Ÿ“Œ 10
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You may recall that in January of 2025, artist Ann Telnaes announced that she had quit The Washington Post after editors killed a cartoon that depicted owner Jeff Bezos, among others, genuflecting to Trump.

This cartoon feels even more relevant this week.

07.02.2026 00:01 ๐Ÿ‘ 6385 ๐Ÿ” 2044 ๐Ÿ’ฌ 71 ๐Ÿ“Œ 48

Didnโ€™t some of your news channels cut this out? Maybe Vance should sue them ๐Ÿ˜

07.02.2026 09:00 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

Well said. Staff continuity, careers, future? Insert โ€œlatest buzzwordโ€= strategy. At this time it still takes scientist time just to weed through wrongly interpreted stuff in various AI applications. Alphafold works well when based on many years of work actually produced by others.

06.02.2026 17:47 ๐Ÿ‘ 4 ๐Ÿ” 2 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0

Harsh. Itโ€™s a lot of work. Celebrate twice!

06.02.2026 17:10 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Top of the photo in white text reads: "BREAKING OVER 680 NATIONAL ACADEMY OF SCIENCES MEMBERS, INCLUDING 10 NOBEL PRIZE LAUREATES, ENDORSE IMPEACHING RFK JR." Below that in black text is a statement reading: "We, the undersigned Members of the National Academy of Medicine, the National Academy of Sciences, and the National Academy of Engineering, writing in our private capacities, endorse the Articles of Impeachment introduced in the House of Representatives on Dec 10, 2025 by Representative Haley Stevens." Below that is the red "STAND UP FOR SCIENCE " logo. Below that is a link in white text reading: "standupforscience.net/impeach-rfkjr".

Top of the photo in white text reads: "BREAKING OVER 680 NATIONAL ACADEMY OF SCIENCES MEMBERS, INCLUDING 10 NOBEL PRIZE LAUREATES, ENDORSE IMPEACHING RFK JR." Below that in black text is a statement reading: "We, the undersigned Members of the National Academy of Medicine, the National Academy of Sciences, and the National Academy of Engineering, writing in our private capacities, endorse the Articles of Impeachment introduced in the House of Representatives on Dec 10, 2025 by Representative Haley Stevens." Below that is the red "STAND UP FOR SCIENCE " logo. Below that is a link in white text reading: "standupforscience.net/impeach-rfkjr".

BREAKING: Over 680 members of the National Academy of Sciences, Medicine, and Engineering have endorsed articles of impeachment against RFK Jr.
(1/2 ๐Ÿงต)

05.02.2026 21:08 ๐Ÿ‘ 6527 ๐Ÿ” 2167 ๐Ÿ’ฌ 69 ๐Ÿ“Œ 94
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Scientists from LSTM and the Centre for Research in Infectious Diseases (CRID) have discovered a new genetic mutation in malaria mosquitoes that causes insecticide resistance in Africa.

Read more: lstm.ac/4qjRWcu.

05.02.2026 11:00 ๐Ÿ‘ 3 ๐Ÿ” 1 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0
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Endogenous retroviruses synthesize heterologous chimeric RNAs to reinforce human early embryo development Zygotic genome activation (ZGA) failure leads to developmental arrest and poses a clinical challenge to womenโ€™s fertility. We observed that human embryos arresting at the eight-cell ZGA stage exhibite...

Endogenous retroviruses synthesize heterologous chimeric RNAs to reinforce human early embryo development
www.science.org/doi/10.1126/...

05.02.2026 11:39 ๐Ÿ‘ 15 ๐Ÿ” 5 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0

Unpopular opinion, including in my own family, but every European nation should boycott this tournament.

05.02.2026 09:48 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Un gรจne antiviral dรฉcouvert chez les moustiques favorise la transmission de la dengue Pourquoi certains moustiques sont-ils plus susceptibles de transmettre la dengue que dโ€™autres ?

๐ŸฆŸ ๐Ÿฆ  Notre รฉquipe du laboratoire "Gรฉnomique ร‰volutive, Modรฉlisation et Santรฉ" (GEMS) @cnrsecologie.bsky.social @pasteur.fr a identifiรฉ un gรจne clรฉ impliquรฉ dans la sensibilitรฉ du #moustique Aedes aegypti au #virus de la #dengue www.inee.cnrs.fr/fr/cnrsinfo/...

05.02.2026 09:00 ๐Ÿ‘ 6 ๐Ÿ” 3 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

Good stuff. And well done Spain, and hopefully other countries will follow. Upsetting all the right people. Whose companies we should of course also avoid.

04.02.2026 10:13 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0