Photograph of the outside of the Max Planck Institute (Nijmegen, the Netherlands) and the trees of the forest around it.
Only a few weeks left to apply for our 4-year PhD position, using human brain organoids & multi-omic methods to study genes implicated in speech disorders. Application deadline 5 Jan 2026. Fellowship is embedded in the International Max Planck Research School. More info: www.mpi.nl/imprs-phd-fe...
And!! Better diagrams 🤩
Very comprehensive resource! And very important work as population decline continues…
📣 Paper alert!
I am delighted that our paper exploring the impact of Neanderthal-derived variants on the activity of a disease-associated craniofacial enhancer has been published in Development today!
journals.biologists.com/dev/article/...
Our new manuscript, led by Emily Corrigan, examines inhibitory neuron diversity across approximately 160 million years of evolutionary divergence, as part of BRAIN Initiative Cell Atlas Network (BICAN) developing brain atlas package: www.nature.com/articles/s41...
What is the cell type closest to neurons in the differentiation tree? The answer will surprise you! (unless you know about development, or were at #MiFoBio2025 listening to Pierre Nassoy's talk)
Photograph of researchers at their benches in the custom-built molecular biology labs of the Max Planck Institute in Nijmegen, with green trees of the forest outside visible through large windows in the background.
Come join us for a 4-year PhD on effects of rare gene disruptions involved in speech disorder, investigated in human neuronal models (via gene-editing, tissue culture, brain organoids, high-res microscopy, transcriptomics, epigenomics).
More info: www.mpi.nl/imprs-phd-fe...
#AcademicJobs #PhDJobs
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🧠 The Lipid #Brain Atlas is out now! If you think #lipids are boring and membranes are all the same, prepare to be surprised. Led by @lucafusarbassini.bsky.social with Giovanni D'Angelo's lab, we mapped membrane lipids in the mouse brain at high resolution.
www.biorxiv.org/cgi/content/...
A big reason it's challenging to work out relationships of early hominins: We know today that the populations of living great apes like gorillas and bonobos have deep ancestry from diverged “ghost” lineages. Our ancestors were surely the same.
www.johnhawks.net/p/genetic-hi...
Yesterday marked the start of my PhD journey with @mps-cognition.bsky.social. We are in Berlin for welcome week, presenting our research interests to each other and attending talks by @mps-cognition.bsky.social fellows. Loved learning about connectomics from @mhlab.bsky.social. Excited for the rest!
Credit: Maayan Harel
Denisovans or their close relatives identified in the fossil record using a gene regulatory phenotyping method. Now out:
www.pnas.org/doi/10.1073/...
It's a wrap for HAAM 2025! Grateful for an intense and inspiring week of exploring #aDNA and #humanpopgen both conceptually and using practical tools. Thank you to all the organisers, instructors and TAs for making this possible!
We are super excited to share our latest pre-print in collaboration with @sonjavernes.bsky.social lab! www.biorxiv.org/content/10.1... : Evolution of the cellular landscape in mammalian striatum 🧠🧬🧵
Very happy to share our new paper on human facial development and evolution out today in JHE 🎉 www.sciencedirect.com/science/arti...
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We're new here—help us spread the word! 🦇 🚀 Please like, follow, and share as we build our presence. We don’t have all the handles yet, so it is difficult tag everyone just yet!! If you are here - let us know 🙌💙
Day 50 cortical organoid stained for KI67 (red), MAP2 (magenta), Hoechst (cyan); image credit: Oliviero Leonardi
DIV 28 iNeuron. Homer1 in green and Synapsin1 in purple showing co-localization of post- and pre-synapses, respectively; image credit: Elly Lewerissa
New preprint 📣! Excited to share the result of several years of work, led by @ellylewerissa.bsky.social & @olivieroleonardi.bsky.social, in collaboration with friends @naelnadifkasri-lab.bsky.social & Giuseppe Testa. On CHD2, a chromatin remodeller, its role in evolution & development [🧵]
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