If you love RNA and RNA machineries as much as we do at @uniregensburg.bsky.social we encourage young scientists who want to start their own lab to apply.
If you love RNA and RNA machineries as much as we do at @uniregensburg.bsky.social we encourage young scientists who want to start their own lab to apply.
π§΅ 1/10 New paper out in @natmicrobiol.nature.com from my postdoc at @mib-wur.bsky.social! π
How eukaryote-like was the archaeal ancestor of eukaryotes? Sequence searches alone can't tell us β so we used protein structure prediction to look deeper. π§¬
www.nature.com/articles/s41...
#OnThisDay in 1938, American evolutionary biologist Lynn Margulis was born. Margulis is most known for developing and popularising the endosymbiotic theory, which explains how eukaryotic cells evolved organelles from simpler prokaryotic organisms that resided within another and became incorporated.
Out Now! Prediction of eukaryotic cellular complexity in Asgard archaea using structural modelling #MicroSky
Pls re-post: My department @oxfordbiochemistry.bsky.social are recruiting for several new faculty positions (links below). Broad search in molecular biology/biochemistry, across prokaryotes and eukaryotes. Interested in understanding life at the molecular level, this job might be for you!
1/n
This is a fantastic paper with a very creative computational approach, that should inspire many "AlphaFlod-predicted shapes" screens.
Great friday read ππ
π¦ Beyond classic probiotics: @schmitzstreitslab.bsky.social lab reveals diverse #Bacteroidota gut strains that block #biofilms of major pathogens. Many also disrupt quorum sensing & show bile salt hydrolase activityβexpanding the #microbiome toolbox against infection.
π buff.ly/sjPk8ZD
Like bacteria, phages use sRNAs to regulate gene expression! Out today in @cp-trendsmicrobiol.bsky.social, @mvelascogomariz.bsky.social and I highlight a recent RIL-seq study from the @saharmelamed.bsky.social lab that looked into posttranscriptional regulation of lambda!
tinyurl.com/lambda-RIL-seq
Join us as Assistant/Associate/Full Professor Computational Biology at Institute of Biology Leiden (IBL) / @leidenscience.bsky.social / @unileiden.bsky.social
Application deadline on 15 March 2026
π
careers.universiteitleiden.nl/job/Assistan...
Rapid modular evolution of antiviral repertoires in P2 phages and their P4 satellites: shuttling, swapping and mixing https://www.biorxiv.org/content/10.64898/2026.02.27.708500v1
Two group leader positions available in the broader areas of RNA science, RNA technologies, and RNA medicine. Attractive packages and a great environment. Come and join us at Helmholtz RNA WΓΌrzburg, Bavaria.
π’ Save the date! The women's talk marathon is back. On Friday 6 March 2026, women from Kiel University β students, staff and professors β will discuss their work and experiences in academia. π©π¬
#WomenInScience #ConnectingHorizons
If you are looking for βmoreβ, apply for this outstanding PhD program which offers you ample opportunities to develop as a scientist and leader connecting to peers, leaders in the RNA field in Germany, Europe and around the world. Learn the science but also about translation into applications.
Congratulations to Sonomi Yamaguchi for her paper at @nature.com. Sonomi discovered Clover defense and explained how nucleotide signals control each step of viral sensing, immune regulation, and viral restriction β named for her beautiful "four-leaf" structures π
www.nature.com/articles/s41...
Our latest preprint: Together with the team of Jan LΓΆwe, @danieltamarit.bsky.social and many others we discovered and characterized several Asgard tubulin genes and propose that microtubule architecture and dynamics evolved in Asgard archaea prior to eukaryogenesis
www.biorxiv.org/content/10.6...
We are happy to share our newest preprint on a novel strain of Ca. Lokiarchaeum ossiferum, that contains an active provirus, capable of excision and independent replication! We propose a novel virus family: Fylgjaviridae.
www.biorxiv.org/content/10.6...
my.corehr.com/pls/uoxrecru...
Two Postdoctoral Research Associates in the Molecular Analysis of Bacterial Outer Membrane Protein Biogenesis
BEN BERKS lab π€©
Long in the making, but happy to present the Chlamydomonas chlororibosome!
Cryo-ETπ¬reveals a large new domain on the small subunit, built from multiple extensions in conserved ribosomal proteins.
bioRxiv π: shorturl.at/q44tG
This suggests greater chlororibosome diversity than expected!
1/n π§΅
Molecular basis for anti-jumbo phage #immunity by AVAST type 5.
Avs5 detects an early jumboβphage activator and halts infection by rapidly hydrolyzing NAD+.
www.sciencedirect.com/science/arti... #phage #bacteriophage #MicroSky
Aarhus University is seeking a Tenure-Track Assistant/Associate Professor in Bioinformatics/Co⦠https://nat.au.dk/en/about-the-faculty/vacant-positions-and-career/job/tenure-track-assistant-professor-associate-professor-in-bioinformatics-and-or-computational-biology-at-aarhus-university-denmark #job
Archaea , archaea everywhere βΊοΈ!
Amazing findings in geometry-based immune activation! Two bacterial defence systems detect phage-encoded ring oligomers, assemble high-order molecular complexes, and trigger abortive infection.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Aude Bernheim @audeber.bsky.social and Eugene Koonin discuss one of most interesting questions in the field connecting bacterial and animal immunity!
www.nature.com/articles/s41...
Fantastic team effort of several groups in the SPP2002 @dfg.de and a brilliant PhD - Eva Herdering in the Kiel team @schmitzstreitslab.bsky.social
𧬠Dive into the small proteome of Methanosarcina mazei (across 5 conditions)! A key resource by @schmitzstreitslab.bsky.social @uni-kiel.de for uncovering #smallproteins functions, motifs and proteoforms in #archaea.
π buff.ly/HJOi3E0
Institut Pasteur (@pasteur.fr) is recruiting new young PIs to open new groups in the Institute. Deadline is February 9th! Don't miss the opportunity!
www.wur.nl/en/vacancy/f...
Become our new colleague (and next door neighbor) and lead a chair/group/department of Biophysics at Wageningen University. Reach out to me for info and please spread!!!
We found a new mode by which bacteria deplete NAD+ to protect from phages. And then we found how phages overcome this defense
Discovered by talented biochemist Dr Ilya Osterman, read the preprint: tinyurl.com/Narp-ap
A thread π§΅
Letβs get this started and on an RNA high π
A new paper from the lab on virus-like particles called eCISs www.nature.com/articles/s41...
How bacteria evolved thousands of precision nanoinjectors?
Some bacteria donβt secrete toxins β they inject them using phage-derived machines called extracellular contractile injection systems (eCISs).