A/Prof Sam Stehbens PhD (She/Her)'s Avatar

A/Prof Sam Stehbens PhD (She/Her)

@samstehbens

Everything microtubules, movement, and microscopy. Melanoma research focus. ARC Future Fellow, lab head University of Queensland #CatsOfAcademia advoCATe. UCSF Wittmann lab alumni.

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Latest posts by A/Prof Sam Stehbens PhD (She/Her) @samstehbens

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All the feels tonight for the Australian biomedical research sector #nhmrc

05.03.2026 10:48 πŸ‘ 6 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0
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β€˜Complete joke’: Efforts to reduce funding wait times ends with longer blowout A long campaign to improve Australia’s sclerotic research bureaucracy has culminated in an extraordinary blowout to grant approval times, leaving scientists despondent.

β€œA complete joke”

After the starting gun fires, Australian researchers have to wait 2–3 years before even starting the race.

Really clear article explaining the impossibly long new time-frames for Australian Research Council grants.

By @liammannix.bsky.social

04.03.2026 00:32 πŸ‘ 58 πŸ” 30 πŸ’¬ 3 πŸ“Œ 1

Sounds like a gummy bear company…

05.03.2026 07:42 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Does anyone know of an anti mStayGold antibody that works for immunoblots / IP? Anyone tried the one from HUABIO (not even sure that’s a real company)? Thanks!

04.03.2026 01:38 πŸ‘ 1 πŸ” 10 πŸ’¬ 2 πŸ“Œ 0
A man standing up in a crowded room of people sitting. He is dressed in workman's clothes and has his head raised as if speaking up when not necessarily belonging there.

A man standing up in a crowded room of people sitting. He is dressed in workman's clothes and has his head raised as if speaking up when not necessarily belonging there.

We are a rich enough country to be funding 37% of all basic research proposals, not just considering "the best" 37% and then maybe only funding 12% in the end.

26.02.2026 01:44 πŸ‘ 1017 πŸ” 167 πŸ’¬ 33 πŸ“Œ 1
Screenshot of LinkedIn post from ARC saying that DP27 EOI outcomes will be released on RMS on the 26th Feb 2026.

Screenshot of LinkedIn post from ARC saying that DP27 EOI outcomes will be released on RMS on the 26th Feb 2026.

The ARC have said (on LinkedIn) they will release outcomes for Discovery Projects Expressions of Interest (2027) tomorrowπŸ‘‡

25.02.2026 03:57 πŸ‘ 36 πŸ” 21 πŸ’¬ 1 πŸ“Œ 4
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Grant delays feared as ARC ramps up β€˜due diligence’ Researchers brace for renewed funding uncertainty as security checks prove β€˜more time-consuming than imagined’

The massive delays ARC announced for all grant schemes – with longer processing times & 3-month announcement windows – were examined in Senate Estimates recently.

Here’s John Ross reporting on it, & the confusing Estimates hearing, for Times Higher EdπŸ‘‡

www.timeshighereducation.com/news/grant-d...

23.02.2026 00:03 πŸ‘ 17 πŸ” 6 πŸ’¬ 1 πŸ“Œ 0

It was a really great meeting- I learnt a lot. Brought together scientists from vastly different areas in such a complementary way. I look forward to seeing it continue.

22.02.2026 10:40 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Blood vessel development and lumenization in a zebrafish embryo. Credit to Dr. Kazuhide Shaun Okuda @latrobeuni.bsky.social. #ZebrafishZunday πŸ§ͺ

22.02.2026 09:45 πŸ‘ 69 πŸ” 19 πŸ’¬ 2 πŸ“Œ 0

Airports have no time zones. Therefore you are correct- never β€˜too early’ πŸ˜†

22.02.2026 06:18 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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a blue dog and an orange dog are standing next to each other and waving ALT: a blue dog and an orange dog are standing next to each other and waving

Michael Krieg, Verena Ruprecht, @felixmendu.bsky.social & Giovanna Petrillo. You have set the bar very high for any Australian conference I help organise πŸ˜† you were wonderful hosts.

22.02.2026 02:30 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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Home from a great #EMBO workshop in Barcelona. Intracellular mechanics & organelle Mechanobiology was such a fun topic! @christanny.bsky.social made sure I didn’t get lost. It was great to catch up with @katemiro.bsky.social 1st time in almost 10yrs!!. Thank you to the hosts.. (continued) 1/2

22.02.2026 02:30 πŸ‘ 17 πŸ” 3 πŸ’¬ 1 πŸ“Œ 0

Do you want to pursue your ideas in computational biology independently, running your group in @embl.orgβ€˜s uniquely collaborative environment, beside world’s most comprehensive biomolecular data resources @ebi.embl.org in Genome Campus next to @sangerinstitute.bsky.social?
Apply to join us & share πŸ™

16.02.2026 07:38 πŸ‘ 15 πŸ” 15 πŸ’¬ 1 πŸ“Œ 0
The ever-changing communication of scientific discovery Nature Biomedical Engineering - We take a look at how scientific articles have evolved over time and envision possible changes to how research findings are communicated in the age of digital media...

"authors also express frustration at the amount of work expected for a single publishable unit, a concern we
share (while humbly noting that it may not be
held by the same authors when they serve as
reviewers of other work)" <-THAT www.nature.com/articles/s41... ht @ritastrack.bsky.social

03.02.2026 21:55 πŸ‘ 28 πŸ” 10 πŸ’¬ 1 πŸ“Œ 0
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I’m likely shouting into the echo chamber here but πŸ‘‰ #DiscoveryScience is so important.

30.01.2026 23:24 πŸ‘ 4 πŸ” 2 πŸ’¬ 0 πŸ“Œ 2
Septins buffer actomyosin forces to protect the nucleus from genotoxic mechanical stress Invasively migrating cells thread their nucleus through confined interstitial spaces. How cells protect the nucleus from intracellular forces is poorly understood. Here, we show that the septin cytoskeleton buffers the actomyosin forces that power nuclear movement. Septin filaments comprising SEPT9, a septin amplified in breast cancer, align with perinuclear actomyosin cables which exhibit higher tensile stress during 3D confined migration through narrower pores. SEPT9 depletion amplifies actin stress during confined migration and after myosin II hyper-activation in non-migrating cells causing actin and nuclear envelope ruptures. Following confined migration, DNA breaks, nuclear blebs, micronuclei and cell death increase in SEPT9-depleted cells, phenotypes rescued by the oncogenic SEPT9 isoform 1. Clinicogenomic data reveal that SEPT9 amplification associates with lower genomic alteration in aggressive breast tumors and higher patient mortality. We propose that septins are a mechanoprotective element of the cytoskeleton, and SEPT9 amplification enhances tumor cell survival by preventing nuclear damage. ### Competing Interest Statement The authors have no competing interests. National Institute of General Medical Sciences, https://ror.org/04q48ey07, 2 R35GM136337-07 National Institute on Aging, https://ror.org/049v75w11, 4 R01AG068908-03

Septins buffer actomyosin forces to protect the nucleus from genotoxic mechanical stress www.biorxiv.org/content/10.6...

23.01.2026 16:07 πŸ‘ 10 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0

#NARF is on bluesky! πŸ‘‰ if you’ve held a fellowship in the last 10 years, you should join.

25.01.2026 01:52 πŸ‘ 1 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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I came here looking πŸ‘€ for a cat. I heard there might be a cat in this tutorial? πŸ˜†

24.01.2026 00:50 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

So excited to share the preprint with the bulk of my PhD work in the Beach @myosincity.bsky.social and Oakes @pwoakes.bsky.social Labs at Loyola University Chicago! We investigate the structure, recruitment, and function of septin networks around the nucleus. A thread:
doi.org/10.64898/202...

23.01.2026 17:45 πŸ‘ 28 πŸ” 15 πŸ’¬ 2 πŸ“Œ 2
Figure 1. Spectraplakins, including MACF1, are large cytoskeletal scaffold proteins that crosslink actin filaments and microtubules to coordinate cellular architecture, polarity, and intracellular organization. This group of proteins has a modular architecture consisting of an N-terminal actin-binding domain, central spectrin-repeat rod regions, and C-terminal microtubule-binding motifs (left). These complex proteins have various functions in neurons, including regulation of neurite outgrowth, axon guidance, synapse organization, and intracellular trafficking (right). Figures from Cusseddu et al. (2021) under a Creative Commons CC BY license.

Figure 1. Spectraplakins, including MACF1, are large cytoskeletal scaffold proteins that crosslink actin filaments and microtubules to coordinate cellular architecture, polarity, and intracellular organization. This group of proteins has a modular architecture consisting of an N-terminal actin-binding domain, central spectrin-repeat rod regions, and C-terminal microtubule-binding motifs (left). These complex proteins have various functions in neurons, including regulation of neurite outgrowth, axon guidance, synapse organization, and intracellular trafficking (right). Figures from Cusseddu et al. (2021) under a Creative Commons CC BY license.

The MACF1 puzzle: when a cytoskeletal giant causes multiple brain disorders | Beyond the Ion Channel

...we just published our new post on why interpreting MACF1 variants is so difficult, highlighting how this massive spectraplakin gene can produce distinct neurodevelopmental phenotypes.

22.01.2026 02:21 πŸ‘ 1 πŸ” 2 πŸ’¬ 0 πŸ“Œ 1

πŸ”¬ Postdoc position – Infection Biology & Cryo-ET (Zurich) πŸ‡¨πŸ‡­
We are looking for a motivated Postdoc to join our interdisciplinary team.
πŸ“© Interested? Check out the job advert:
www.imm.uzh.ch/dam/jcr:cb17...

πŸ‘‰ More info on the lab: www.weiss-laboratory.com
Please share with interested colleagues!

19.01.2026 13:15 πŸ‘ 29 πŸ” 23 πŸ’¬ 0 πŸ“Œ 3
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Interested in cell-cell communication and microscopy? We are searching for a motivated postdoctoral researcher to join MΓΌnster! Please Apply! @uni-muenster.de

19.01.2026 16:54 πŸ‘ 22 πŸ” 24 πŸ’¬ 1 πŸ“Œ 0

New from the lab: we report the development of our glutamine biosensor, iGlo, and use iGlo to study spatial and temporal dynamics of glutamine metabolism. Plasmids are being deposited with Addgene!

19.01.2026 20:48 πŸ‘ 7 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0

I purchased a kindle for my daughter- she asked for one after watching me read mine. I too worry we’ll lose reading as a hobby. 😞 too much quick fix dopamine in reels & tiktoks

13.01.2026 10:59 πŸ‘ 2 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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Not my cat but very much my cat’s vibe. #CatsOfAcademia

08.01.2026 00:39 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

I have an Australian spotted gum cutting board 70x50cm. Problem is- it’s too beautiful to cut on!

30.12.2025 00:58 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

I’m considering baking a second ham…because 6kg apparently wasn’t enough to last a week

27.12.2025 08:04 πŸ‘ 1 πŸ” 0 πŸ’¬ 2 πŸ“Œ 0

I'm on the Board of @biologists.bsky.social. Many know them as publishers of @dev-journal.bsky.social, @jcellsci.bsky.social, @jexpbiol.bsky.social , DMM, and @biologyopen.bsky.social --but they also are a major funder of small grants that empower young biologists and enable scientific meetings πŸ§ͺ

22.12.2025 12:26 πŸ‘ 64 πŸ” 21 πŸ’¬ 0 πŸ“Œ 0

Having seen a NFC at a show. You’d know. THEYR’E HUGE. πŸ˜†

21.12.2025 22:29 πŸ‘ 4 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Ha- I mean 2025. Clearly- I’m in next year mode already

17.12.2025 04:39 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0