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Andrea Jones, PhD

@dr-andrea-jones

Postdoctoral Fellow, Segura Lab @ Duke Leading Edge Fellow University of Michigan BME PhD Alum Virginia Tech Hokie Forever endocrinology meets biomaterials women's health & aging

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06.03.2025
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Latest posts by Andrea Jones, PhD @dr-andrea-jones

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Transcriptomic and proteomic dynamics of ovarian follicle group culture resemble in vivo folliculogenesis The prohibitively low yield of fertilizable oocytes obtained from cultured ovarian follicles limits clinical translation of in vitro follicle maturation for fertility preservation. This is in part due...

My pre-print from the Shikanov Lab is live! We detail oocyte and somatic transcriptome, and whole follicle proteome signatures driving folliculogenesis in vitro towards improved ART. www.biorxiv.org/content/10.1...

26.09.2025 17:35 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
Miao et al. link early-pregn ancy maternal gut microbiom e to preterm birth, identifying Clostridium innocuum and its estradiol-degra ding gene enriched in women with preterm birth. C. innocuum degrades estradiol and interacts with host genetics to amplify risk. These findings propose estradiol-degrad ing bacteria as predict ive biomarkers and therapeutic targets for preterm birth.

Miao et al. link early-pregn ancy maternal gut microbiom e to preterm birth, identifying Clostridium innocuum and its estradiol-degra ding gene enriched in women with preterm birth. C. innocuum degrades estradiol and interacts with host genetics to amplify risk. These findings propose estradiol-degrad ing bacteria as predict ive biomarkers and therapeutic targets for preterm birth.

Researchers identify bacteria in the maternal gut microbiome linked to a higher risk of preterm birth. www.cell.com/cell-host-mi...

@cp-cellhostmicrobe.bsky.social
#WestLakeUniversity Ju-Sheng Zheng & colleagues

10.09.2025 15:00 πŸ‘ 10 πŸ” 4 πŸ’¬ 2 πŸ“Œ 1
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Engineers transform dental floss into needle-free vaccine New method places inactivated viruses directly into mice’s gums

In an unorthodox study, researchers invented a special kind of floss that can protect against infectious disease. In the process, they had to do something no scientist had done before-- try to floss a mouse.

My newest in @science.org 🐁🦷

www.science.org/content/arti...

23.07.2025 15:08 πŸ‘ 103 πŸ” 26 πŸ’¬ 2 πŸ“Œ 3
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Is sex at birth a biological coin toss? Insights from a longitudinal and GWAS analysis Offspring sex may not be randomβ€”maternal age and genetics influence sex clustering within families.

Sex at birth may not be purely random, according to a new
#ScienceAdvances study.

Instead, each family’s likelihood of having only male or only female children is a β€œweighted coin toss” influenced by maternal age and genetics. scim.ag/3ILwz3O

24.07.2025 16:44 πŸ‘ 58 πŸ” 10 πŸ’¬ 0 πŸ“Œ 1
Illustration of a scientist holding her child's hand while talking to colleagues. Text says: Making myself visible as a grad student parent

Illustration of a scientist holding her child's hand while talking to colleagues. Text says: Making myself visible as a grad student parent

"Despite my discomfort and the potential for backlash, I need to make myself visible as a single parent and to advocate for change."

On #NationalParentsDay, read about how this researcher has advocated for more support for grad student parents. scim.ag/3UpZSLJ

27.07.2025 14:07 πŸ‘ 46 πŸ” 8 πŸ’¬ 0 πŸ“Œ 0
Single-oocyte transcriptional profile of early-stage human oocytes reveals differentially expressed genes in the primordial and transitioning stages The critical initial step in human oocyte maturation - the transition of ovarian follicles from dormancy to activation - remains poorly understood. Here we performed RNA sequencing on single oocytes i...

Check out our pre-print! www.researchsquare.com/article/rs-6...

03.07.2025 09:48 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Dolce vita: a four-step guide to stress-free holidays from academia Three-month summer holidays as a child in northwest Italy helped Stefano Sandrone to hone his relaxation and holiday-planning skills. Here’s his advice for scientists.

Three-month summer holidays as a child in northwest Italy helped Stefano Sandrone to hone his relaxation and holiday-planning skills. Here’s his advice for scientists

https://go.nature.com/4kCp1yt

11.06.2025 10:08 πŸ‘ 17 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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Male mice can grow ovaries if their pregnant mums are iron deficient Nature - The study is the first to show that low iron levels can affect fetal sexual development.

Male mouse fetuses can develop female organs in utero if their mother is iron deficient during pregnancy

https://go.nature.com/3FTDeaZ

09.06.2025 18:28 πŸ‘ 28 πŸ” 8 πŸ’¬ 0 πŸ“Œ 3
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Fellows | leadingedgesymposium Congratulations to the 2025 Leading Edge Fellows!

so grateful to be named one of this year’s fellows!
www.leadingedgesymposium.org/fellows

28.05.2025 10:13 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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You’re only human: a six-step strategy to surviving your PhD Graduate students are not machines. Behaving like one during your programme will leave you frustrated and unfulfilled, says Gauthier Weissbart.

Graduate students are not machines. Behaving like one during your programme will leave you frustrated and unfulfilled

https://go.nature.com/3RSKTss

16.04.2025 09:41 πŸ‘ 46 πŸ” 11 πŸ’¬ 0 πŸ“Œ 3
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β€œFertilization President” Trump Just Gutted Fertility Research An entire research team at the CDC has been dismissed, thanks to Donald Trump’s cuts.

Despite dubbing himself the β€œFather of IVF,” Donald Trump actually WILL NOT be funding federal infertility research.

Trump has fired an entire infertility research team at the CDC.

03.04.2025 00:51 πŸ‘ 1294 πŸ” 660 πŸ’¬ 69 πŸ“Œ 57
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From bench to bread: how science can enhance your hobbies Researchers describe how they are using skills honed in the laboratory in their creative pursuits.

Researchers describe how they are using skills honed in the laboratory in their creative pursuits

https://go.nature.com/4jkH8Ii

03.04.2025 10:08 πŸ‘ 43 πŸ” 10 πŸ’¬ 0 πŸ“Œ 2
PRAMS Shuttered for Good In the first weeks of the administration I wrote a number of...

Everyone who works for PRAMS (the Pregnancy Risk Assessment Monitoring System) at CDC was terminated today. That appears to be the end of a critical program which monitored infant and maternal health nationwide across pregnancy, childbirth & postpartum. talkingpointsmemo.com/edblog/prams...

01.04.2025 22:11 πŸ‘ 4599 πŸ” 2416 πŸ’¬ 330 πŸ“Œ 397
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Single-cell analysis comparing early-stage oocytes from fresh and slow-frozen/thawed human ovarian cortex reveals minimal impact of cryopreservation on the oocyte transcriptome - PubMed This work was funded by National Institutes of Health (NIH) R01HD099402, Career Training in Reproductive Biology (CTRB) Training Grant National Institutes of Health (NIH) T32 to Jordan Machlin, Nation...

Congratulations to the new Dr. Jordan Machlin and the Shikanov Lab the latest publication on single-cell analysis of human oocytes. We spent many, many hours searching for eggs under the microscope πŸ”¬ and found minimal differences in fresh vs. cryopreserved oocytes.
pubmed.ncbi.nlm.nih.gov/39919251/

21.03.2025 18:50 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Michelle Oyen, PhD - Digital Twins for Pregnancy and Engineering The Female Experience MOTHER-podcast with Karina Vazirova Β· Episode

thoroughly enjoyed listening to this fantastic interview with @michelleoyen.bsky.social on the MOTHER podcast! it will be truly amazing to watch the next generation of women in STEM take on amazing engineering challenges to advance women's health ✨
open.spotify.com/episode/4hhs...

21.03.2025 18:45 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0