At Immunoschool, @gitlinlabmsk.bsky.social will show how VEXAS syndrome is reshaping our understanding of immune aging, late-onset inflammatory disease & new routes to immunotherapy. A powerful 🔗 between clonal hematopoiesis & systemic inflammation.
Register FREE: www.eventbrite.com/e/internatio...
When immune cells go senescent, the whole body may follow. But next generation immunotherapies like CAR-T cells and vaccines targeting senoantigens could help us fight back. Don't be a 🧟♀️ and 😴 on this opportunity to hear how we can target senescence:
FREE sign-up: www.eventbrite.com/e/internatio...
New @cp-cancercell.bsky.social review by @brownlab1.bsky.social & @miriammerad.bsky.social highlights tools to re-engineer the myeloid system—from CAR-Ts to targeted, TME reprogramming LNPs—and turn immunosuppressive tumor macrophages into potent tumor killers 🧐 www.sciencedirect.com/science/arti...
What if aging begins in the youngest immune cells? Emmanuelle Passegué reveals how changes in hematopoietic stem cells drive declining immunity, inflammaging & disease risk, and how restoring them could rebuild resilience.
Program: immunoschool.org
Register FREE: www.eventbrite.com/e/internatio...
Guido Kroemer joins the 2026 Immunoschool to highlight the hallmarks of immune aging and how they drive decline. Aging hallmarks—from genomic instability to inflammaging—are interconnected & potentially targetable.
See what's on immunoschool.org
FREE to register www.eventbrite.com/e/internatio...
The immune system profoundly shapes aging as it interacts with every organ. New single-cell & spatial tools now map where this relationship breaks down and where interventions support healthy longevity. More @ Immunoschool
Program: immunoschool.org
Register (free): www.eventbrite.com/e/internatio...
3 days. Global faculty and learners of all career stages. Aging, immunity and translation at the cutting edge.
Save your spot: www.eventbrite.com/e/internatio...
Explore the program: immunoschool.org
The second speaker will be Vishwa Deep Dixit of the Yale Univertsity Center for Research on Aging
📣 Immunoschool 2026 is open for registration 📣
Explore how immunotherapy can promote healthy longevity, from targeting senescent cells to rejuvenating exhausted immunity and reducing inflammaging.
FREE, online March 23–25.
Program: immunoschool.org
Register: www.eventbrite.com/e/internatio...
In IL-12.aFOLR2.CAR–treated tumors, cancer cells are closely juxtaposed with GZMB⁺ CD8⁺ T cells, consistent with antigen-dependent cytotoxic engagement. But that's not the only way the cancer cells die! To find out more, see the paper for full data, figures and the amazing co-authors!
This resulted in tumor control in models of disseminated ovarian and lung cancer, even though the CAR T cells were not targeting cancer cells.
At low dose and without prior lymphodepletion, this therapy triggered a profound resetting and reprogramming of the TME, with significant infiltration of endogenous CD8 T cells reactive to tumor cells and immunostimulatory CXCL9+ macrophages.
We describe IL-12–armored CAR T cells that target tumor-associated macrophages rather than cancer cells, by recognizing the tumor macrophage markers FOLR2 or TREM2. We show these CAR T cells both kill immunosuppressive tumor macrophages and localize IL-12 activity within the tumor microenvironment.
I am thrilled to announce that our latest paper is out now in @cp-cancercell.bsky.social! 1/n www.sciencedirect.com/science/arti...
New **RESOURCE** in @natcancer.nature.com - a landmark single-cell Immune Atlas of multiple myeloma—1.3M+ bone marrow cells from 337 patients. Led by the Immune Atlas Consortium with major contributions from Sacha Gnjatic, @edgargk.bsky.social & HIMC profiling teams 🧐 www.nature.com/articles/s43...
📣 VIRTUAL TOWNHALL 📣
This Friday. Organized by NY-CURES & postdoc unions ✍️ >>> docs.google.com/forms/d/e/1F...
Find out how the proposed Empire Biomedical Research Institute can help solve issues NY State is grappling with: affordability, workforce stability and long-term health & economic growth.
A whimsical, vintage-style Christmas illustration shows Santa Claus flying in a sleigh over Albany, New York. Santa wears a vibrant blue-green suit with white fur trim and holds a scroll titled "This Year’s Nice List," featuring items like "New tools for prevention, diagnostics, and therapeutics" and "Supported postdocs and early-career scientists." His sleigh, shaded in coordinating tones of teal and blue-green, is overflowing with scientific lab equipment such as test tubes, microscopes, and conical tubes. Cheerful reindeer, each dressed in tiny white lab coats, pull the sleigh through a snowy, star-filled sky. Below, Albany’s Capitol buildings glow warmly amid a snowy landscape, completing the festive and science-themed scene.
New York’s research ecosystem delivered plenty of “nice list” rewards this year. Now we need Albany to deliver EBRI so we can keep that impact growing. Research is the gift that keeps on giving, so for a healthier and wealthier New Year for all New Yorkers, sign our letter to 🎅 >>> c.org/hwy54dWJDb
Need more info before signing petition for state-backed research institute? Get the full behind-the-scenes 🎞️ of how the Empire Biomedical Research Institute proposal came to be, what’s needed to move it forward, and how other states can follow suit: keypoint.keystonesymposia.org/home/shruti-...
🗞️ in @gothamist.com from @clewisreports.bsky.social.
Our 2 cents: EBRI doesn’t compete with other urgent needs — it equips NYS to meet them. Not funding it now worsens pressures; funding it grows the economy to help fix them.
State-backed research is a win-win-win-win. gothamist.com/news/ny-medi...
🚨 REVIEW 🚨
Amir Horowitz & Peter Heeger in @natrevneph.nature.com highlight how diverse NK cells in the kidney support immune surveillance but also drive injury in many diseases and contribute to transplant damage, with high-resolution profiling revealing new therapeutic targets. 🧐 rdcu.be/eUgor
Petition for a NY Biomedical Institute. This is a no-brainer to support science in NY, similar to programs in CA/TX.
www.change.org/p/support-a-...
Wondering why you should ✍ our petition? c.org/nDnRNSsVcq
In @aai.org, founder @drshrutinaik.bsky.social reveals why the coalition was formed, why NY needs a state-backed research institute, and how scientists should organize for systemic support — here and nationwide.
news.aai.org/2025/11/20/n...
Run a lab? Work in a lab? Wondering where your future research funding will come from?
New York has an unprecedented opportunity on the table — a bold proposal to supercharge biomedical research and innovation across the state.
👉 Sign the petition & share to help make it happen.: c.org/TDMy2H9JTW
We’re in a proud, confident and ambitious Empire State of mind! If you believe in building a better and brighter tomorrow, hustle on over to sign and share the petition for an Empire Biomedical Research Institute to fuel the future and the people like you who power discovery. c.org/hwy54dWJDb
📢 SIGN & SHARE THE PETITION! 📢
New York needs an Empire Biomedical Research Institute to create new statewide funding opportunities for scientists & physician-scientists so that patients and their families get the life-saving and life-changing new therapeutics they're hoping for ✏️ c.org/TDMy2H9JTW
With co-authors Bram Teunissen & @yizhoudonglab.bsky.social, we dive into emerging ways to make LNPs more precise—from tuning their chemistry to reprogramming RNA expression and even controlling protein stability & localization >>> a road🗺️ for more intelligent delivery & broader applications ahead.
A major hurdle for next-gen LNPs? We still don’t have great tools to see where they go or what they do in vivo.
Tracking the nanoparticle, RNA cargo, and protein output in real time is key to designing smarter, more targeted systems.
Our new review in @natbiomedeng.nature.com is out!
RNA-loaded lipid nanoparticles (LNPs) have huge potential—but their strong liver and immune cell uptake has mostly confined them to vaccines and liver therapies. We explore how to move beyond those limits.
free to read 🔗 rdcu.be/eLxGs
E11 Bio is excited to unveil PRISM technology for mapping brain wiring with simple light microscopes. Today, brain mapping in humans and other mammals is bottlenecked by accurate neuron tracing. PRISM uses molecular ID codes and AI to help neurons trace themselves.
Read more: e11.bio/blog/prism
Add your name ✍ at www.nycures.org so Albany sees 10,000 scientists calling for the future of biomedical research to be built right here in New York.
Our first email to members goes out soon—introducing the statewide biomedical institute we’re proposing and how you can help power it forward.
Wondering what *exactly* we’re up to?
Our first coalition email is about to go out—introducing the statewide biomedical institute we’re proposing and how you can help power it forward THIS WEEK!
Sign up now so you don’t miss it: www.nycures.org/
