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Happy to share our new preprint on the mechanism of human tRNA 3' CCA maturation! This project was spearheaded by Bernhard Kuhle in my group, with contributions from many others and a great collaboration with the group of Peter Rehling (UMG). See highlights below!
www.biorxiv.org/content/10.6...
When they say that they are now βunshackledβ from βstupid rules of engagementβ while using AI to provide targeting information, this is the outcome. Terrible.
Text from the article outlining a simplistic model of measles vaccine escape risk.
Monoclonal antibody therapies are being developed to treat #measles in response to its recent resurgence. David A Kennedy argues that such therapies risk driving measles virus evolution in ways that might undermine the protection offered by #vaccination. π§ͺ
plos.io/3OJx6q4
FT comments section this morning - saying what everyone else is thinking, right?
Super Early Bird deadline Sunday 8 Mar! Save β¬100
Register for Machines on Genes 2026 βοΈπ§¬
Biochemical Society Harden Conference
π Heraklion, Crete | 8β11 June 2026 πβοΈ
www.eventsforce.net/biochemsoc/f...
Scientific organisers: Lori Passmore, Dana Branzei & Alessandro Costa
They killed 180 children and their teachers in a double-tap strike on a school. The girls were 7 to 12 years old.
Out now! In collaboration with Leifu Chang, we uncover the molecular and structural underpinnings of CRISPR-Cas12f-like RNA-guided transcription systems!
Links to the published articles:
tinyurl.com/55kpavet
tinyurl.com/sk6djwx3
Previous thread for the preprint:
bsky.app/profile/did:...
I know they were ordered some time ago, but I believe the delivery of the E/Fs has been postponed and they have not entered service there.
AFAIK Kuwait does not have Super Hornets (yet). Looks like it was a legacy F/A-18C with AIM-9 Sidewinders at short range. Yikes.
Isnβt this more like the βok, maybe no WMDs but Saddam was a bad person and deserved to be removedβ part?
When Hegseth says "no stupid rules of engagement," this is what he means.
Number two, media. Your job is not to pass along what the military and the regime want you to communicate, dressed up as independent βreportingβ. Your JOB is to tell us what they do NOT want us to hear about.
FIFA will "monitor developments" in Iran following the outbreak of military action by the United States -- the co-hosts of this summer's men's World Cup -- against the Middle Eastern nation, which has qualified for the tournament and is due to play its group games in the U.S. President Donald Trump, who was given the FIFA Peace Prize by FIFA president Gianni Infantino in December, announced the commencement of missile strikes on Iran on Saturday, calling the mission a "major combat operation."
FIFA closing monitoring the situation.
The situation: Their peace prize winner just bombed one of the countries he will host at the World Cup this summer
"Trying to compete with Reform not only feels inauthentic... but a betrayal of what Labour is supposed to represent. We must address the concerns and fears of voters, not play on them."
Damning stuff from Sadiq Khan
www.theguardian.com/commentisfre...
I am a big fan of pedantry, but we have to acknowledge that the F-22, while designed as an air superiority fighter, can employ JDAMs and other air-to-ground munitions and flew several hundred strike sorties in Syria.
fell for it again award
"The forgotten majority" being the 71% who didn't vote for you.
π
This week's cover @thelancet.com
It is time we stop this madness. Just because you can, doesn't mean you should. We have to stop these billionaires ruining our planet.
I am so grateful to the Blavatnik Family Foundation and the New York Academy of Sciences for this honor. Canβt wait to be back to the lab and celebrate with lab members on this special recognition of their hard work.
Reminder: the entire NSF budget is 9B and NIH like 47B. And they have 500B that they donβt know how to spend.
I and my USG colleagues would go to external meetings where lunch would be served and to follow the rules we had to pay for our sandwiches.
And one last shot, taken a few hours before our flight back home. π
Incredible opinion. It holds that the common ICE tactic of jumping out of an unidentified rental vehicle and seizing suspected noncitizens while masked violates the Fourth Amendment because the *manner* of the seizure is incompatible with a free society governed by the rule of law.
π¨New preprint! We built a cell-free genomics platform (GATO-seq) to probe transcriptional regulation and discovered a βsuper pauseβ sequence that triggers a new Pol II active-site conformation. Huge shout-out to @robertovn.bsky.social for pulling off this monster of a project. tinyurl.com/superpause
A collage of 12 photos showing scenes captured in Vietnam, including cityscapes during/after sunset, bridges, market places, and lantern boats.
It's (almost) a wrap. After a bit more than two weeks in highly photogenic Vietnam, it is time to head home and face the world again. #travelphotography #nikon
South Korea joins Brazil in knowing what to do with coup plotters and insurrectionists.