Basil Greber's Avatar

Basil Greber

@bjgreber

Structural biologist. High-resolution imaging of macromolecular assemblies (and landscapes). MRC career development fellow/group leader at the Institute of Cancer Research, London. Views my own.

2,532
Followers
513
Following
1,128
Posts
26.10.2023
Joined
Posts Following

Latest posts by Basil Greber @bjgreber

πŸ‘€

07.03.2026 17:32 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Happy to share our new preprint on the mechanism of human tRNA 3' CCA maturation! This project was spearheaded by Bernhard Kuhle in my group, with contributions from many others and a great collaboration with the group of Peter Rehling (UMG). See highlights below!

www.biorxiv.org/content/10.6...

05.03.2026 21:43 πŸ‘ 20 πŸ” 13 πŸ’¬ 1 πŸ“Œ 0

When they say that they are now β€œunshackled” from β€œstupid rules of engagement” while using AI to provide targeting information, this is the outcome. Terrible.

06.03.2026 07:44 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Text from the article outlining a simplistic model of measles vaccine escape risk.

Text from the article outlining a simplistic model of measles vaccine escape risk.

Monoclonal antibody therapies are being developed to treat #measles in response to its recent resurgence. David A Kennedy argues that such therapies risk driving measles virus evolution in ways that might undermine the protection offered by #vaccination. πŸ§ͺ
plos.io/3OJx6q4

05.03.2026 09:10 πŸ‘ 6 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0
Post image

FT comments section this morning - saying what everyone else is thinking, right?

05.03.2026 07:15 πŸ‘ 17116 πŸ” 5972 πŸ’¬ 513 πŸ“Œ 493

Super Early Bird deadline Sunday 8 Mar! Save €100
Register for Machines on Genes 2026 βš™οΈπŸ§¬
Biochemical Society Harden Conference
πŸ“ Heraklion, Crete | 8–11 June 2026 πŸŒŠβ˜€οΈ

www.eventsforce.net/biochemsoc/f...

Scientific organisers: Lori Passmore, Dana Branzei & Alessandro Costa

03.03.2026 18:36 πŸ‘ 5 πŸ” 5 πŸ’¬ 0 πŸ“Œ 0

They killed 180 children and their teachers in a double-tap strike on a school. The girls were 7 to 12 years old.

05.03.2026 04:33 πŸ‘ 4380 πŸ” 1808 πŸ’¬ 101 πŸ“Œ 30

Out now! In collaboration with Leifu Chang, we uncover the molecular and structural underpinnings of CRISPR-Cas12f-like RNA-guided transcription systems!

Links to the published articles:
tinyurl.com/55kpavet
tinyurl.com/sk6djwx3

Previous thread for the preprint:
bsky.app/profile/did:...

04.03.2026 20:28 πŸ‘ 68 πŸ” 26 πŸ’¬ 0 πŸ“Œ 2

I know they were ordered some time ago, but I believe the delivery of the E/Fs has been postponed and they have not entered service there.

04.03.2026 16:37 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

AFAIK Kuwait does not have Super Hornets (yet). Looks like it was a legacy F/A-18C with AIM-9 Sidewinders at short range. Yikes.

04.03.2026 16:06 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
04.03.2026 03:36 πŸ‘ 696 πŸ” 198 πŸ’¬ 5 πŸ“Œ 6

Isnβ€˜t this more like the β€œok, maybe no WMDs but Saddam was a bad person and deserved to be removed” part?

04.03.2026 09:02 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Post image

When Hegseth says "no stupid rules of engagement," this is what he means.

03.03.2026 04:40 πŸ‘ 241 πŸ” 107 πŸ’¬ 8 πŸ“Œ 5

Number two, media. Your job is not to pass along what the military and the regime want you to communicate, dressed up as independent β€œreporting”. Your JOB is to tell us what they do NOT want us to hear about.

02.03.2026 17:41 πŸ‘ 9 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
FIFA will "monitor developments" in Iran following the outbreak of military action by the United States -- the co-hosts of this summer's men's World Cup -- against the Middle Eastern nation, which has qualified for the tournament and is due to play its group games in the U.S.

President Donald Trump, who was given the FIFA Peace Prize by FIFA president Gianni Infantino in December, announced the commencement of missile strikes on Iran on Saturday, calling the mission a "major combat operation."

FIFA will "monitor developments" in Iran following the outbreak of military action by the United States -- the co-hosts of this summer's men's World Cup -- against the Middle Eastern nation, which has qualified for the tournament and is due to play its group games in the U.S. President Donald Trump, who was given the FIFA Peace Prize by FIFA president Gianni Infantino in December, announced the commencement of missile strikes on Iran on Saturday, calling the mission a "major combat operation."

FIFA closing monitoring the situation.
The situation: Their peace prize winner just bombed one of the countries he will host at the World Cup this summer

01.03.2026 18:29 πŸ‘ 300 πŸ” 73 πŸ’¬ 8 πŸ“Œ 6
Preview
Labour must stop channelling Reform and unite with progressives. That’s the lesson from Gorton and Denton | Sadiq Khan The threat to the party in some parts of our country is now existential. But we can progress, as we have in London, by being bold and strong in our core beliefs, says London mayor Sadiq Khan

"Trying to compete with Reform not only feels inauthentic... but a betrayal of what Labour is supposed to represent. We must address the concerns and fears of voters, not play on them."

Damning stuff from Sadiq Khan

www.theguardian.com/commentisfre...

01.03.2026 07:20 πŸ‘ 2522 πŸ” 683 πŸ’¬ 98 πŸ“Œ 53

I am a big fan of pedantry, but we have to acknowledge that the F-22, while designed as an air superiority fighter, can employ JDAMs and other air-to-ground munitions and flew several hundred strike sorties in Syria.

28.02.2026 10:02 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Post image

fell for it again award

28.02.2026 07:09 πŸ‘ 8889 πŸ” 1681 πŸ’¬ 71 πŸ“Œ 54
Post image

"The forgotten majority" being the 71% who didn't vote for you.

27.02.2026 05:31 πŸ‘ 618 πŸ” 125 πŸ’¬ 18 πŸ“Œ 15

πŸ‘€

27.02.2026 06:23 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Post image

This week's cover @thelancet.com

26.02.2026 23:48 πŸ‘ 3116 πŸ” 1458 πŸ’¬ 44 πŸ“Œ 80

It is time we stop this madness. Just because you can, doesn't mean you should. We have to stop these billionaires ruining our planet.

26.02.2026 09:12 πŸ‘ 101 πŸ” 49 πŸ’¬ 3 πŸ“Œ 0

I am so grateful to the Blavatnik Family Foundation and the New York Academy of Sciences for this honor. Can’t wait to be back to the lab and celebrate with lab members on this special recognition of their hard work.

25.02.2026 19:58 πŸ‘ 81 πŸ” 11 πŸ’¬ 5 πŸ“Œ 2

Reminder: the entire NSF budget is 9B and NIH like 47B. And they have 500B that they don’t know how to spend.

21.02.2026 16:37 πŸ‘ 93 πŸ” 56 πŸ’¬ 2 πŸ“Œ 1

I and my USG colleagues would go to external meetings where lunch would be served and to follow the rules we had to pay for our sandwiches.

22.02.2026 19:00 πŸ‘ 1603 πŸ” 302 πŸ’¬ 37 πŸ“Œ 3
Post image

And one last shot, taken a few hours before our flight back home. πŸ‘‹

21.02.2026 22:50 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Incredible opinion. It holds that the common ICE tactic of jumping out of an unidentified rental vehicle and seizing suspected noncitizens while masked violates the Fourth Amendment because the *manner* of the seizure is incompatible with a free society governed by the rule of law.

21.02.2026 00:51 πŸ‘ 11815 πŸ” 3925 πŸ’¬ 107 πŸ“Œ 128
Video thumbnail

🚨New preprint! We built a cell-free genomics platform (GATO-seq) to probe transcriptional regulation and discovered a β€œsuper pause” sequence that triggers a new Pol II active-site conformation. Huge shout-out to @robertovn.bsky.social for pulling off this monster of a project. tinyurl.com/superpause

19.02.2026 14:24 πŸ‘ 49 πŸ” 12 πŸ’¬ 0 πŸ“Œ 1
A collage of 12 photos showing scenes captured in Vietnam, including cityscapes during/after sunset, bridges, market places, and lantern boats.

A collage of 12 photos showing scenes captured in Vietnam, including cityscapes during/after sunset, bridges, market places, and lantern boats.

It's (almost) a wrap. After a bit more than two weeks in highly photogenic Vietnam, it is time to head home and face the world again. #travelphotography #nikon

19.02.2026 16:13 πŸ‘ 34 πŸ” 0 πŸ’¬ 2 πŸ“Œ 0

South Korea joins Brazil in knowing what to do with coup plotters and insurrectionists.

19.02.2026 14:56 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0