The movie shows an AlphaFold model of QT45 in complex with eight magnesium ions (the number of authors on the paper ☺). The model beyond a couple of G-C base pairs (zoomed in in the movie) remains questionable.
Congratulations to my colleagues Edoardo Gianni @edogia.bsky.social, Sam Kwok, Kevin Goeij, Bryce Clifton @bryceclifton.bsky.social, and group leader Phil Holliger @philholliger.bsky.social, as well as everyone involved in this elegant discovery!
Self-replicating molecules such as RNA are considered a plausible foundation for the origin of life on Earth. A remarkably small RNA molecule of only 45 nucleotides (QT45) that can synthesize itself and its complementary strand is now published in Science: www.science.org/doi/10.1126/...
That’s beautiful work. Congratulations!
Jeremy is an excellent scientist and leader. Highly recommended!
Wow!!
Congratulations! The channel lattices are very intriguing, and the figures are beautiful as always!
Tomas Malinauskas presented his research at the University of Helsinki, Finland, on 25 August 2025.
Tomas Malinauskas after completing the Björn Borg Helsinki Marathon in 2025.
Thanks to everyone who donated to @cancerresearchuk.org via my giving page (fundraise.cancerresearchuk.org/page/tomass-...) and supported me in completing the marathon in Helsinki! Many thanks to Dr. Johanna Syrjänen for organising my talk on BMP signalling at @helsinki.fi, and to all who attended!
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All donations go directly to Cancer Research UK.
Thank you! 🙏
— Tomas
@cancerresearchuk.org
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I’m deeply grateful to my family, friends & colleagues for their generosity 💙
Please consider supporting Cancer Research UK through my Giving Page:
🔗 fundraise.cancerresearchuk.org/page/tomass-...
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Today, Finland is at the frontier of the democratic world, helping to protect our way of life in Europe & beyond.
I’m proud to show support for our Nordic friends during my visit.
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Why Helsinki? 🇫🇮
Not just for the ideal 2–13 °C running weather!
I spent a semester at the University of Helsinki via Erasmus, where I first experienced world-class research.
That inspired me to apply for my Cancer Research UK studentship at Oxford.
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Most of our research is published in peer-reviewed journals (see PubMed or Google Scholar).
Running this marathon is my way to thank Cancer Research UK — and to share how scientists contribute to the fight against cancer.
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Over the years, my colleagues & I have revealed how cells “talk” to each other by mapping proteins in 3D at atomic resolution.
These mechanisms often fail in cancer.
Understanding them could lead to new treatments 💡🔬
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I’m a structural biologist, studying how molecules in our cells work.
This helps us understand what goes wrong in cancer — and how we might fix it.
Cancer Research UK funded my PhD at Oxford & continues to support my research today 🙏
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Why Cancer Research UK?
1 in 6 deaths worldwide is caused by cancer.
Mortality rates have fallen since the 1990s thanks to better science & treatments — but progress depends on continued research into the biology behind cancer.
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Hi everyone 👋
I’m running the Helsinki Marathon 2025 to support Cancer Research UK 🏃♂️💙
Please consider donating through my Giving Page:
🔗 fundraise.cancerresearchuk.org/page/tomass-...
Prof. Christopher Garcia (Stanford) speaking at Oxford University on June 10, 2025.
Prof. Christopher Garcia (Stanford) speaking at Oxford University on June 10, 2025.
One great thing about Oxford: lectures by the smartest minds. This week’s highlight: Prof. Christopher Garcia (Stanford) on TCRs — from 90s crystal structures to deorphanization & immuno-oncology. Thanks to Dr Ricardo Fernandes for organizing!
