Author Thursdays take 🏡 points:
vEEG w/ quant EEG analysis is a sensitive, non-invasive way to confirm transient ⬆️ ICP
⬆️ ICP in a patient w/ a history of malignancy should ⬆️ suspicion for carcinomatous meningitis or a structural lesion.
@CodyLNathan
@EEG_MD
👉 Should IV milrinone use be recommended?NOT YET, but the MIVAR study (RCT, NCT04362527) may provide some answers soon.
@kloubkloub
@SigLasocki
Author Thursdays take 🏡 points:
👉 Yes, IV milrinone be used as a short-term therapeutic test!
👉 It's possible IV milrinone be used alone (a ‘vasodilatory-only’ approach), rather than in combination with induced arterial hypertension
Wang et al: Comparative Effectiveness of Different Targeted Temperature Management Modalities for Adult Patients with Traumatic Brain Injury
Link: link.springer.com/ar...
@neurocritical #neurocritcare
Villegas et al: Effect of Desmopressin on Attaining Therapeutic Hypernatremia with Hypertonic Saline Continuous Infusion in Intracranial Hemorrhage
Link: link.springer.com/ar...
@neurocritical #neurocritcare
Mulder et al: Systematic Review of Direct Hospital Costs Associated with Aneurysmal Subarachnoid Hemorrhage Management
Link: link.springer.com/ar...
@neurocritical #neurocritcare
Bhardwaj et al: From fMRI to Family Meeting: Clinician and Family Perspectives on Neurotechnology-Informed Shared Decision-Making in Disorders of Consciousness
Link: link.springer.com/ar...
@neurocritical #neurocritcare
👉 While initial results in a small selective cohort appear encouraging, real-world adoption of non-invasive PSI needs further evaluation and validation.
@Mainalishraddha
@neurocritical
Author Thursdays take 🏡 points:
👉Pulse Shape Index (PSI) from non-invasive 🧠 sensors shows promise as a surrogate for invasive ICP waveform analysis
👉 PSI reflects 🧠 compliance, not just mean ICP, offering insight into 🧠 pressure dynamics beyond transient changes.
Maldonado-Luna et al: Radiomics Versus the Human Eye: Rethinking SEBES for Prognostic Stratification in Aneurysmal Subarachnoid Hemorrhage
Link: link.springer.com/ar...
@neurocritical #neurocritcare
Pernod et al: An Atypical Crossed Cerebellar Diaschisis in Septic Encephalopathy: Lessons from a Diagnostic Detour
Link: link.springer.com/ar...
@neurocritical #neurocritcare
Eagle et al: Trajectories of daily inpatient blood biomarkers of physiological function improve mortality and morbidity prognostic model performance for patients with severe traumatic brain injury
Link: link.springer.com/ar...
@neurocritical #neurocritcare
Rigby et al: Recognizing Intracranial Hypertensive Crisis in Leptomeningeal Disease: Insights from a Case of Dynamic Bone Flap Angulation
Link: link.springer.com/ar...
@neurocritical #neurocritcare
Loggini et al: Early Tracheostomy in Patients with Nontraumatic Intracerebral Hemorrhage is Associated with Lower in-Hospital Complications and Reduced Resource Use Without Increased Mortality
Link: link.springer.com/ar...
@neurocritical #neurocritcare
👉 NP scores further delineate neurologic outcomes in OHCA survivors with bilaterally intact somatosensory evoked potentials
Thuhien N
Author Thursdays take 🏡 points:
👉 "NP score" quantitates severity of hypoxic ischemic 🧠injury on MRIs and correlates w/ neuro outcomes on discharge for OHCA survivors.
👉 Computational modeling of 🧠 MRI-based NP scores identifies predictive probabilities of neuro outcomes
Mazzio et al: Association of EEG Response to Hypertonic Saline and Neurologic Outcomes in Pediatric Acute Brain Injury
Link: link.springer.com/ar...
@neurocritical #neurocritcare
Bitar et al: Medical Decision-Making and Process Measures in a Consultative Hub-and-Spoke Teleneurocritical Care Network
Link: link.springer.com/ar...
@neurocritical #neurocritcare
Madzar et al: Guidelines for Neuroprognostication in Critically Ill Adults with Status Epilepticus
Link: link.springer.com/ar...
@neurocritical #neurocritcare
Du et al: Development and Validation of a Novel Nomogram for Risk Stratification of Posthemorrhagic Chronic Hydrocephalus Following Intraventricular Hemorrhage: A Multicenter Retrospective Cohort Study
Link: link.springer.com/ar...
@neurocritical #neurocritcare
Gritti et al: Visualizing and Interpreting the Carbon Dioxide Reactivity Index in Traumatic Brain Injury
Link: link.springer.com/ar...
@neurocritical #neurocritcare
👉 Our findings support initiating VTE prophylaxis 24-48 hours post-injury; however, high-quality prospective studies focused on the severe TBI population are needed.
@MichaelYangMD
@BrijKarmur
@JennaMannMD
@dr_alexleung
#neurocritcare
Author Thursdays take 🏡 points:
👉 Early cVTEp initiation in sTBI associated with ⬇️ odds of VTE, and ☠️ benefit when initiated ≤48h.
👉 Early initiation 🚫⬆️ 🧠 🩸progression or the need for neurosurgical 🔪.
Feil et al: Ketogenic Diet in Super-Refractory Status Epilepticus: A Retrospective Cohort Study with Severity-Matched Controls in Critically Ill Adults
Link: link.springer.com/ar...
@neurocritical #neurocritcare
Wijdicks: Myokymia and Autonomic Dysreflexia After Brain Death
Link: link.springer.com/ar...
@neurocritical #neurocritcare
Chuck et al: Impact of Circle of Willis Anatomical Variations on Outcomes in Aneurysmal Subarachnoid Hemorrhage
Link: link.springer.com/ar.....
@neurocritical #neurocritcare
Journaux et al: Comparison of the Efficacy of Polyvalent Intravenous Immunoglobulins and Therapeutic Plasma Exchange in Anti-NMDAR Encephalitis in the ICU
Link: link.springer.com/ar...
@neurocritical #neurocritcare
Banker et al: Prophylactic Antiseizure Medication in Patients with Lobar Intracerebral Hemorrhage
Link: link.springer.com/ar...
@neurocritical #neurocritcare
Sameeullah et al: Fifth Toe Abduction in Brain Death/Death by Neurologic Criteria: Description of a New Spinal Reflex
Link: link.springer.com/ar...
@neurocritical #neurocritcare
