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Miki Ebisuya

@ebisuyamiki

Synthetic developmental biologist at PoL TU Dresden. Cross-species comparison and manipulation of the ORGANOID ZOO. https://physics-of-life.tu-dresden.de/team/pol-groups/ebisuya

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16.11.2024
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Latest posts by Miki Ebisuya @ebisuyamiki

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We have a new paper out today from superstar Nora Herzog!

A virus that fluidizes the nucleus to enable replication!

Check it out here:

lnkd.in/e-xV8acK

This was an amazing collaboration with Ian Mohr and Angus Wilson

05.03.2026 17:27 πŸ‘ 14 πŸ” 6 πŸ’¬ 1 πŸ“Œ 0

Had an absolutley brilliant time at #KSEmbryology26 a few weeks ago and was really inspired by all the great talks and posters there 🀩 Here's a list of the #preprints I noticed from presenters πŸ‘‡ - check it out and please let me know if I've missed any!

prelights.biologists.com/prelists/key...

05.03.2026 10:32 πŸ‘ 5 πŸ” 3 πŸ’¬ 1 πŸ“Œ 0

Final version @nature.com of our paper describing unconventional multicellular development in a choanoflagellate inhabiting an extreme environment. A ton of new data since the first @biorxivpreprint.bsky.social preprint (which we've kept updating).

A brief 🧡 (carried over from the old place)

28.02.2026 08:12 πŸ‘ 339 πŸ” 137 πŸ’¬ 16 πŸ“Œ 16
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Protocol for quantifying vertebral column morphology for the statistical analysis of scoliosis severity in zebrafish Here, we present a protocol for quantifying zebrafish vertebral column morphology using micro-computed tomography (microCT) datasets for scoliosis researchers. We describe steps for orientation of ske...

Our newest work on quantification and statistical testing of scoliosis severity using microCT and R. www.cell.com/star-protoco... Thanks to @eceatayeter.bsky.social @brittneyvoigt

27.02.2026 19:46 πŸ‘ 12 πŸ” 6 πŸ’¬ 1 πŸ“Œ 1
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AI tools can design genomes. Will they upend how life evolves? Breakthroughs in computing are supercharging a field of science dedicated to building synthetic organisms from scratch.

Nice review from Kate Adamala of Adrian Woolfson's new book On The Future of Species.
www.nature.com/articles/d41...

26.02.2026 21:17 πŸ‘ 8 πŸ” 2 πŸ’¬ 1 πŸ“Œ 0
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The molecular evolution of vertebrate organs Nature Ecology & Evolution - This Review discusses recent advances in the molecular evolution of vertebrate organs, including rates of evolution of organs and cell types, molecular mechanisms...

Our internal organs are evolutionary marvels. New technologies are transforming our understanding of the evolution of vertebrate organs. You can find more by reading here:
rdcu.be/e5EgU
#EvoBio #EvoDevo πŸŸπŸ¦ŽπŸ’πŸ¦‡πŸŠπŸ¦œ

25.02.2026 12:29 πŸ‘ 139 πŸ” 52 πŸ’¬ 2 πŸ“Œ 5
Redirecting

Our most recent work on the β€œfunction and evolution” of #nuclear-speckles is now online at Cell @cp-cell.bsky.social
doi.org/10.1016/j.ce...
Read the threadπŸ‘‡ for the highlights of our findings.

25.02.2026 16:01 πŸ‘ 122 πŸ” 59 πŸ’¬ 9 πŸ“Œ 5
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From our new paper out now in @currentbiology.bsky.social: www.cell.com/current-biol... w/ @neurofishh.bsky.social @gkafetzis.bsky.social @denilsson.bsky.social

Looking across animals, the vertebrate eye is an obvious outlier. Why is it so different that other highly visual animals?

24.02.2026 10:45 πŸ‘ 108 πŸ” 39 πŸ’¬ 1 πŸ“Œ 2
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Tissue phase transitions in development: more than just mechanics Summary: Tissue material phase transitions are classically thought to regulate tissue deformability. This Review emphasises their unexpected roles in directly influencing growth and patterning signall...

Excited to share our new review in @dev-journal.bsky.social on tissue phase transitions during development!

@karengrace12.bsky.social @nicolettapetridou.bsky.social

πŸ”— doi.org/10.1242/dev....

19.02.2026 13:31 πŸ‘ 72 πŸ” 26 πŸ’¬ 2 πŸ“Œ 2

Looking forward to @keystonesymposia.bsky.social, @ebisuyamiki.bsky.social and @jun-wu-lab.bsky.social's #KSEmbryology26 meeting starting this evening? Feel free to come say hi and grab a poster for your lab/office

17.02.2026 19:26 πŸ‘ 6 πŸ” 3 πŸ’¬ 0 πŸ“Œ 1
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The heartbeat and other bodily processes play a surprising role in shaping perception and cognition. (From the archive) www.quantamagazine.org/how-your-hea...

14.02.2026 23:32 πŸ‘ 26 πŸ” 6 πŸ’¬ 0 πŸ“Œ 0
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Here is a robust biochemical & functional difference between young and old mammalian cells:

- The fraction of new amino acids incorporated into proteins.

The difference is consistent, quantitative, cell-type specific, and deeply intriguing.

What aging mechanisms cause it ?

1/

13.02.2026 13:36 πŸ‘ 21 πŸ” 7 πŸ’¬ 1 πŸ“Œ 1
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Feb 11 is International Day of Women and Girls in Science and at RIKEN BDR, we celebrate the achievements of #womeninscience by holding an IDWGIS Symposium. We also recently launched Mirai Alliance, a mentorship network for women researchers in life sciences. www.bdr.riken.jp/en/news/bdr-...

11.02.2026 00:01 πŸ‘ 7 πŸ” 3 πŸ’¬ 2 πŸ“Œ 0
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Oriented cell divisions induce basal progenitors and regulate neural expansion across tissues and species A fundamental role for division orientation in progenitor output driving cortical and retinal growth is revealed.

Happy to announce that our latest paper is now out! Have you ever wondered how neural tissues control their size? In this paper, we show that cell division orientation is critical in both the cortex and retina. www.science.org/doi/10.1126/...

04.02.2026 19:16 πŸ‘ 92 πŸ” 31 πŸ’¬ 5 πŸ“Œ 2
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βš‘πŸ‘©β€πŸ”¬Electrical signals are key for promoting organ regenerative growth, a new study!

Out now in Science Advances, from the Mateus group @ritamateus.bsky.social at PoL and @mpi-cbg.de along with the lab of Frank JΓΌlicher @mpipks.bsky.social

Read the news here: tud.link/7jzptz
Video:©️ Mateus group

05.02.2026 10:02 πŸ‘ 47 πŸ” 15 πŸ’¬ 0 πŸ“Œ 2
an insect, a bird, and an elephant visualized with unit height scaling. insect is landscape shaped and the elephant is portrait shaped

an insect, a bird, and an elephant visualized with unit height scaling. insect is landscape shaped and the elephant is portrait shaped

Why is it that small animals like insects have a landspace body plan when viewed head-on, but larger animals like elephants are taller than wide?

With @m-v.bsky.social, we find out in our new preprint titled 'Size and shape of terrestrial animals' - arxiv.org/html/2602.00...

03.02.2026 18:36 πŸ‘ 27 πŸ” 9 πŸ’¬ 0 πŸ“Œ 1
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Remodeling of XIST regulatory landscape during primate evolution How gene regulation strategies rapidly evolve across short evolutionary timescales is explored.

Our paper on the evolution of XIST regulatory network in primates is now published in Science Advances! Check out the paper www.science.org/doi/10.1126/... or a digest of our findings emmanuelczt.github.io/posts/2026/0... A short 🧡 of our main findings πŸ‘‡

28.01.2026 15:48 πŸ‘ 35 πŸ” 14 πŸ’¬ 1 πŸ“Œ 0
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AlphaGenome is out in @nature.com today along with model weights! 🧬

πŸ“„ Paper: www.nature.com/articles/s41...

πŸ’» Weights: github.com/google-deepm...

Getting here wasn’t a straight path. We discussed the story behind the model, paper & API in the following roundtable: youtu.be/V8lhUqKqzUc

28.01.2026 21:02 πŸ‘ 83 πŸ” 39 πŸ’¬ 4 πŸ“Œ 1
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Really excited to share our new paper in @nature.com! We uncovered how a physical instability of the cytoplasm coupled with the cell cycle drives cytoplasmic partitioning in early embryos #zebrafish #drosophila. Read more in this🧡 www.nature.com/articles/s41... 🀩
@poldresden.bsky.social @mpi-cbg.de

28.01.2026 16:10 πŸ‘ 204 πŸ” 67 πŸ’¬ 4 πŸ“Œ 10
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Resolving forebrain developmental organisation by analysis of differential growth patterns - Nature Communications Experiments on the embryonic chick brain reveal distinct directional growth patterns and a tripartite hypothalamus, challenging the classic segmented prosomere model and offering an updated view of ho...

Excited to finally share the final/final.doc version of our paper. It's been a journey, but very proud of the result. Well done to all involved, especially @elsieplace.bsky.social

@kchinnaiya.bsky.social , @thomasdwkim.bsky.social, @sethblackshaw.bsky.social πŸ‘πŸ‘

www.nature.com/articles/s41...

26.01.2026 10:23 πŸ‘ 15 πŸ” 6 πŸ’¬ 0 πŸ“Œ 0
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Chirality of malaria parasites determines their motion patterns - Nature Physics Malaria parasites move on helical trajectories when infecting their hosts. Now it is shown that they use right-handed chirality to control their motion patterns, and that this chirality is linked to t...

(1/2) Our work with @freddyfrischknecht.bsky.social on the chirality of malaria parasites has found its home in the January issue of @natphys.nature.com:

www.nature.com/articles/s41...

Moreover, we are very happy that it comes with a news and views article πŸ‘β€οΈπŸ˜€

23.01.2026 08:58 πŸ‘ 17 πŸ” 9 πŸ’¬ 1 πŸ“Œ 0
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β€˜Remote controlled’ proteins illuminate living cells The discovery that some fluorescent proteins are sensitive to magnets could lead to the development of switchable drugs and biosensors.

Researchers have engineered magnetically controlled fluorescent proteins that can be remotely dimmed and brightened in cells and living animals

go.nature.com/3NUSY12

21.01.2026 17:46 πŸ‘ 55 πŸ” 22 πŸ’¬ 4 πŸ“Œ 1
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Four camera-type eyes in the earliest vertebrates from the Cambrian Period - Nature Early vertebrates, particularly myllokunmingids, possessed four camera-type eyes (a pair of lateral eyes and pineal and parapineal organs), which indicates that these structures functio...

New paper presenting rather compelling evidence that the stem-vertebrate Haikouichthys had paired lateral and supranumerary medial eyes (!!!), and proposing that the medial eyes may have deep homology with the pineal and parapineal organs.

www.nature.com/articles/s41...

21.01.2026 17:47 πŸ‘ 66 πŸ” 30 πŸ’¬ 2 πŸ“Œ 8

True! The tree was slightly tilted, so probably there was a sun shade

21.01.2026 16:12 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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A loving family of tiny bats in Panama πŸ¦‡πŸ¦‡πŸ¦‡
Likely resting on a tree trunk due to the lack of nearby caves.

Fascinating how they remain upside down even while clinging on.

21.01.2026 14:30 πŸ‘ 9 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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@marineluciano.bsky.social recreates intestinal Villi geometry by growing epithelial cells on wavy rolling substrates. Unexpected intrication of curvature effects is observed. Thanks to all! @caterinatomba.bsky.social @sgabriele.bsky.social @sciencesunige.bsky.social
www.biorxiv.org/content/10.6...

20.01.2026 10:24 πŸ‘ 51 πŸ” 17 πŸ’¬ 1 πŸ“Œ 2
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An ancient genome duplication event drives the development and evolution of spinnerets in spiders A genome duplication event during the Silurian played a crucial role in the evolutionary emergence of spinnerets in spiders.

More than 400 million years ago, during the Silurian Period, an evolutionary event led to the later emergence of spiders’ spinneretsβ€”the abdominal organs that make silkβ€”according to new #ScienceAdvances research. https://scim.ag/4sFX3pJ

16.01.2026 19:15 πŸ‘ 61 πŸ” 14 πŸ’¬ 2 πŸ“Œ 0
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How ground squirrels enhanced their retinas - Scientific editing and writing experts - Life Science Editors Scientific editing and writing experts for manuscripts and grants

Nice summary on our paper on mechanisms controlling development and evolution of the cone-dominant ground squirrel retina, which is now in final form at eLife.
www.lifescienceeditors.com/2026/01/06/h...

08.01.2026 14:02 πŸ‘ 23 πŸ” 7 πŸ’¬ 1 πŸ“Œ 1
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A light-entrained clock mechanism in a hydrozoan jellyfish synchronizes evening gamete release Jellyfish rely on light cues to help coordinate the timing of their gamete release. By characterizing a new species of jellyfish, this study reveals an additional autonomous circadian mechanism that s...

Now out in PLOS Biology- a novel clock mechanism regulating spawining in a newly-identified Clytia species
: dx.plos.org/10.1371/jour...

07.01.2026 19:26 πŸ‘ 25 πŸ” 10 πŸ’¬ 1 πŸ“Œ 0
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Excited to share Alison's @alisonkickuth.bsky.social paper from the lab out in @nature.com this week! We uncovered how a mechanical ratchet mechanism drives cytokinesis in early #zebrafish embryos. Read more in this thread 🧡 and at www.nature.com/articles/s41... 🀩
@poldresden.bsky.social @mpi-cbg.de

07.01.2026 16:02 πŸ‘ 150 πŸ” 60 πŸ’¬ 8 πŸ“Œ 5