Keri Martinowich

Coal trains passing under the Manchester Bridge

for #fluorescencefriday we have the dance of blood vessels by @mind-western.bsky.social @shahrzadbahrampour.bsky.social @nadiahaghbinphd.bsky.social and Vladislav Novikov

microscope image showing green and red dots

Orai1 (Green) colocalizing with STIM1 (Red) in HEK cells using STED microscopy #fluorescencefriday

Confocal micrograph of a mouse embryonic fibroblast with membrane labeled in blue, nuclei in yellow and cellular cytoplasm in red.

Happy #FluorescenceFriday! Here is a mouse fibroblast with multiple thin membrane extensions reaching out toward its neighbors. The long (>10 um) extensions are a type of signaling filopodia called #cytonemes that transport signals like SHH, WNT, Notch, and GFs! 🔬 by Senior Scientist Hong Lin. 🧪 👩‍🔬

An image of frog photoreceptors but in a top down view, so it looks like a fuzzy shag carpet.

Happy #FluorescenceFriday Here is a whole mount frog retina. Every once in a while (also in sagittal sections) I see some very thin rods groups together (in this image I pseudocolored them green). I haven't verified it, but frogs have red and green rods, and I'm wondering if that's what they are.

Cells use proteins like morphogens to talk to each other in order to build and maintain 3D tissue structures. But how do these morphogens reach distant cells when they are all packed together? We think long #cytonemes play a big role in shaping how cells talk to one another for growth.

These brain cells clear proteins that contribute to Alzheimer’s When specialized cells called tanycytes stop working, disease-causing tau proteins build up in the brain.

When specialized cells called tanycytes stop working, disease-causing tau proteins build up in the brain.

go.nature.com/4ldhrez

In imaging-based spatial transcriptomics (Xenium CosMx), 40% RNAs are Not assigned to segmented cells

This amazing preprint @fabiantheis.bsky.social studies the origin, heterogeneity & biological inference (Modeling cell protrusion/contacts😎) of unassigned RNAs

www.biorxiv.org/content/10.6...

With this science piece, there's considerable unrest today about what NSF will fund. My understanding is that NSF on-the-ground is that what falls under the umbrellas of AI and quantum is broad. If you are submitting, consider helping them.

www.science.org/content/arti...

Finally I can join #FluorescenceFriday as a theorist 😊.

This is a DNA-PAINT recording of E-Cadherin and F-actin in Drosophila embryonic epidermis. You can see E-cadherin clusters and their counterparts across junctions. Cover in @biophysj.bsky.social . doi.org/10.1016/j.bp... #devbio #cellbio

Two neurobiologists win 2026 Brain Prize for discovering mechanics of touch Research by Patrik Ernfors and David Ginty has delineated the diverse cell types of the somatosensory system and revealed how they detect and discriminate among different types of tactile information.

Two neurobiologists who helped decipher how the somatosensory system detects touch and pain have won this year’s Brain Prize, the largest award in neuroscience.

By @helenak.bsky.social

#neuroskyence

www.thetransmitter.org/somatosensat...

Cell types: encoding the brain's BIOS Inferring the structure of primary rewards from connectomics

What are cell types good for, computationally? Encoding innate behavior! In this 2-parter, I break down the relationship between cell types—which I had, in years prior, dismissed as mere implementation detail—and computation. I changed my mind!

www.neuroai.science/p/cell-types...

Warm congratulations to The Brain Prize winners 2026, Professor David Ginty and Professor Patrik Ernfors, for their pioneering work on how the nervous system detects and processes touch and pain.

Karolinska Institutet
HHMI

#Neuroscience #BrainPrize2026

UC Irvine Center for Addiction Neuroscience (ICAN) Symposium - Charlie Dunlop School of Biological Sciences Bridging the Lab and the Clinic to Address Addiction and Comorbid Affective and Psychosis Disorders Please register below for the UC Irvine Center for Addiction Neuroscience (ICAN) Symposium on Wednes...

Interested in addiction and cormorbid disorders?
Join us for our ICAN symposium on Mar. 18 in @ucirvine.bsky.social, featuring Josh Gordon, @neurovoice.bsky.social, Tony George, @nanopharmnc.bsky.social, Khaled Moussawi, Meg Fox, Firoza Mamdani, & more! All welcome!
www.bio.uci.edu/event/ican-s...

NIH Office of Extramural Research announcements of feedback sessions for NIH-wide strategic plan for March 16 and April 8.

IMPORTANT---IMPORTANT---IMPORTANT

NIH is seeking input for the NIH-wide Strategic Plan. Open to everyone but Registration is Required!

Your chance to listen and get your 2 or more cents in.

grants.nih.gov/news-events/...

A dorsal hippocampus-prodynorphinergic dorsolateral septum-to-lateral hypothalamus circuit mediates contextual gating of feeding Goode et al. show that prodynorphin (Pdyn)-expressing neurons of the dorsolateral septum (DLS) receive substantial dorsal hippocampal (DHPC) input and inhibit lateral hypothalamic (LHA) GABAergic neur...

Restaurants, billboards, commercials… what brain circuits link context to appetite? 🧠🌎🍽️

Very happy to finally share a major update in our work exploring the hippocampus and lateral septum in calibrating food consumption! 🍩

Major thanks to our lab and collaborators! ⭐️⭐️

www.cell.com/neuron/fullt...

Got stunning fluorescence microscopy images? 🌈🔬 SDB wants to feature YOUR work for #FluorescenceFriday! We highlight images from SDB members with a short description and the image creators 📸. Fill out the form to be featured: docs.google.com/forms/d/e/1F...

Congrats Josh! Really exciting to see this - we have been thinking about a molecular connectomics experiment in human brain profiling both the LC and amygdala - I'm excited to chat more with you about this idea to hear your perspective in light of these data!

A neuromodulatory circuit-to-molecular pathway for reformatting aversive memories during recall Tan et al. identify a neuromodulatory circuit-to-molecular pathway in rats that updates aversive memories when they are recalled. Noradrenaline from the locus coeruleus triggers synapse-to-nuclear tra...

Excited to share our new paper:
We uncover a locus coeruleus→amygdala circuit linking β-adrenergic signaling to transcription regulation in defined amygdala cells during memory reconsolidation—+ stress or elevated noradrenergic signaling at recall can strengthen memory.
www.cell.com/neuron/abstr...

UAB is recruiting neuroscience faculty at two different levels - come join our vibrant neuroscience community!

Semi-close-up of a cluster of penstemon seedheads with snow on top of them

These goth beardtongue seedheads looked great in the snow today. They’re eaither penstemon digitalis or penstemon hirsutus; I have a mix of both.

This photo is part of my ongoing quest to appreciate the beauty in the non-blossom parts of the garden.

#maryland #nativeplants

Lack of reviewers threatens robustness of neuroscience literature Simple math suggests that small groups of scientists can significantly bias peer review.

Broad peer review is crucial for a healthy scientific literature, but neuroscientists turn down review requests too often. Simple math suggests that small groups of scientists can significantly bias the literature, writes @jvoigts.bsky.social.

#neuroskyence

www.thetransmitter.org/publishing/l...

See public.csr.nih.gov/EvaluationIn...

This is figure 2, which shows global diversification dynamics of six diverse butterfly families.

Butterflies and moths are key indicators of functioning and healthy ecosystems. A Review in Nature Reviews Biodiversity describes the evolutionary history of the order Lepidoptera and tracks shifts in researchers’ understanding of the clade in the genomic era. go.nature.com/4r0kbgS 🌍 🧪

Has anyone heard what happens with chartered members whose terms aren’t finished yet? Have they been notified?

They are going from 10 to 15 study sections (surprising) - public.csr.nih.gov/EvaluationIn...

NAL is dead

NMB is dead

ARM is dead

Some shit is about to go down with NIH study sections, friends. Keep your eyes peeled for change that may affect your grant submissions.

Family friend who runs this - South Point Oyster Farm, which is located at the intersection of the Sinepuxent and Newport sections of Chincoteague Bay!

Meet the neuroscientist running for Congress Sam Wang, a neuroscientist running for the U.S. House of Representatives, has been interested in “fixing bugs in democracy” for decades.

Neuroscientist @samwang.bsky.social, whose research implicated the cerebellum in autism, now hopes to “fix bugs in democracy”—by running for Congress.

By Lauren Schenkman

#neuroskyence

www.thetransmitter.org/policy/is-th...