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Blandine

@blandinep84

French-british Biomedical scientist at the University of Liverpool, working on osteoarthritis research.

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15.11.2024
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Latest posts by Blandine @blandinep84

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Back to work next week after 7 months maternity leave. I'm both excited to return to a job I love and worked hard to get. But dreading it: how am I going to manage a tough academic career and two wonderful babies? How did you academic mamas do it?

05.03.2026 13:22 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

"faster, reproducible science across disciplines through UKRI‑supported national AI testbeds and shared methods"

Forgive me for expressing scepticism that AI will magically fix the reproducibility crisis.

23.02.2026 20:04 πŸ‘ 26 πŸ” 7 πŸ’¬ 4 πŸ“Œ 0

Important too to validate in the tissue/ sample/species you are using! Some sample processing may modify antigens and antibody binding.

24.02.2026 13:32 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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Why Bax detection in >1400 publications might be flawed - Cell Death & Disease Cell Death & Disease - Why Bax detection in >1400 publications might be flawed

"Here, we show that this Ab appears to be unreliable due to providing false-positive signals at the expected molecular weight of Bax in immunoblotting experiments and likewise provides false-positive signals in immunofluorescence-based detection of Bax expression"

www.nature.com/articles/s41...

25.12.2024 19:20 πŸ‘ 47 πŸ” 15 πŸ’¬ 5 πŸ“Œ 3
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Openness means more than access. That's why we encourage submissions of Replication Studies.

Learn about publishing your replication study with us in our author guide: buff.ly/rcI0oAY

22.02.2026 09:21 πŸ‘ 12 πŸ” 5 πŸ’¬ 0 πŸ“Œ 0

Measles is one of those nightmare diseases that, if it hadn't been killing people for hundreds of years, people would ABSOLUTELY be pushing conspiracy theories about right now. It's too nasty in too many different directions to seem natural. But oh, boy, it sure is.

15.02.2026 18:52 πŸ‘ 1260 πŸ” 359 πŸ’¬ 10 πŸ“Œ 39

First-rate analysis.

Strong agree that β€˜someone needs to own disciplinary health’ . At present, a fatal flaw of the UK system, centred in England on the separation of functions between DfE (and OfS) and DSIT, is that no one does.

15.02.2026 13:44 πŸ‘ 15 πŸ” 9 πŸ’¬ 0 πŸ“Œ 0

"Science β€” especially curiosity-driven research β€” is, at its heart, a creative act. It needs space to breathe and the capacity to fail. Often, government-mandated programmes lack that flexibility" .

13.02.2026 16:36 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Science funding needs fixing β€” but not through chaotic reforms The changes announced by a major UK science funder are putting scientists β€” and the future of research β€” in a difficult position.

www.nature.com/articles/d41... Excellent summary by @prof-tregoning.bsky.social @natureportfolio.nature.com @ukri.org

13.02.2026 15:16 πŸ‘ 6 πŸ” 3 πŸ’¬ 1 πŸ“Œ 1

Also: shifting scientific funding towards "government priority areas" is a surefire way to kill creativity and innovation.

Generating scientific knowledge is not like ordering a takeaway. You can't just tick the 'science' that you want and expect anything useful.

09.02.2026 22:06 πŸ‘ 16 πŸ” 6 πŸ’¬ 0 πŸ“Œ 1
Abstract: Under the banner of progress, products have been uncritically adopted or
even imposed on users β€” in past centuries with tobacco and combustion engines, and in
the 21st with social media. For these collective blunders, we now regret our involvement or
apathy as scientists, and society struggles to put the genie back in the bottle. Currently, we
are similarly entangled with artificial intelligence (AI) technology. For example, software updates are rolled out seamlessly and non-consensually, Microsoft Office is bundled with chatbots, and we, our students, and our employers have had no say, as it is not
considered a valid position to reject AI technologies in our teaching and research. This
is why in June 2025, we co-authored an Open Letter calling on our employers to reverse
and rethink their stance on uncritically adopting AI technologies. In this position piece,
we expound on why universities must take their role seriously toa) counter the technology
industry’s marketing, hype, and harm; and to b) safeguard higher education, critical
thinking, expertise, academic freedom, and scientific integrity. We include pointers to
relevant work to further inform our colleagues.

Abstract: Under the banner of progress, products have been uncritically adopted or even imposed on users β€” in past centuries with tobacco and combustion engines, and in the 21st with social media. For these collective blunders, we now regret our involvement or apathy as scientists, and society struggles to put the genie back in the bottle. Currently, we are similarly entangled with artificial intelligence (AI) technology. For example, software updates are rolled out seamlessly and non-consensually, Microsoft Office is bundled with chatbots, and we, our students, and our employers have had no say, as it is not considered a valid position to reject AI technologies in our teaching and research. This is why in June 2025, we co-authored an Open Letter calling on our employers to reverse and rethink their stance on uncritically adopting AI technologies. In this position piece, we expound on why universities must take their role seriously toa) counter the technology industry’s marketing, hype, and harm; and to b) safeguard higher education, critical thinking, expertise, academic freedom, and scientific integrity. We include pointers to relevant work to further inform our colleagues.

Figure 1. A cartoon set theoretic view on various terms (see Table 1) used when discussing the superset AI
(black outline, hatched background): LLMs are in orange; ANNs are in magenta; generative models are
in blue; and finally, chatbots are in green. Where these intersect, the colours reflect that, e.g. generative adversarial network (GAN) and Boltzmann machine (BM) models are in the purple subset because they are
both generative and ANNs. In the case of proprietary closed source models, e.g. OpenAI’s ChatGPT and
Apple’s Siri, we cannot verify their implementation and so academics can only make educated guesses (cf.
Dingemanse 2025). Undefined terms used above: BERT (Devlin et al. 2019); AlexNet (Krizhevsky et al.
2017); A.L.I.C.E. (Wallace 2009); ELIZA (Weizenbaum 1966); Jabberwacky (Twist 2003); linear discriminant analysis (LDA); quadratic discriminant analysis (QDA).

Figure 1. A cartoon set theoretic view on various terms (see Table 1) used when discussing the superset AI (black outline, hatched background): LLMs are in orange; ANNs are in magenta; generative models are in blue; and finally, chatbots are in green. Where these intersect, the colours reflect that, e.g. generative adversarial network (GAN) and Boltzmann machine (BM) models are in the purple subset because they are both generative and ANNs. In the case of proprietary closed source models, e.g. OpenAI’s ChatGPT and Apple’s Siri, we cannot verify their implementation and so academics can only make educated guesses (cf. Dingemanse 2025). Undefined terms used above: BERT (Devlin et al. 2019); AlexNet (Krizhevsky et al. 2017); A.L.I.C.E. (Wallace 2009); ELIZA (Weizenbaum 1966); Jabberwacky (Twist 2003); linear discriminant analysis (LDA); quadratic discriminant analysis (QDA).

Table 1. Below some of the typical terminological disarray is untangled. Importantly, none of these terms
are orthogonal nor do they exclusively pick out the types of products we may wish to critique or proscribe.

Table 1. Below some of the typical terminological disarray is untangled. Importantly, none of these terms are orthogonal nor do they exclusively pick out the types of products we may wish to critique or proscribe.

Protecting the Ecosystem of Human Knowledge: Five Principles

Protecting the Ecosystem of Human Knowledge: Five Principles

Finally! 🀩 Our position piece: Against the Uncritical Adoption of 'AI' Technologies in Academia:
doi.org/10.5281/zeno...

We unpick the tech industry’s marketing, hype, & harm; and we argue for safeguarding higher education, critical
thinking, expertise, academic freedom, & scientific integrity.
1/n

06.09.2025 08:13 πŸ‘ 3790 πŸ” 1897 πŸ’¬ 110 πŸ“Œ 390

All I hear from ukri is blablabla... In the meantime we're left in limbo not knowing how to prepare (because projects take months if not years to be ready for funding application).

06.02.2026 12:51 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Their answers to this fiasco is unimpressive. It makes no sense and they're just throwing us all unde the bus. I'm starting to think they're hiding something worse.. Why else would they do something so drastic and destructive.

06.02.2026 11:37 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

As the political climate around animal research becomes less supportive in the UK, it is our interest to argue for & protect organismal biology.

BBSRC opened a survey, which gives us a timely platform. Please fill & share link among colleagues. Deadline: 9/2

engagementhub.ukri.org/mrc-bbsrc/la...

03.02.2026 09:17 πŸ‘ 7 πŸ” 8 πŸ’¬ 1 πŸ“Œ 1

Last week, RPN broke a string of stories on significant changes to funding across a number of research councils (see thread below)

This morning, UKRI chief executive is appearing at the Commons science committee, where he is being asked about them by MPs

Here are some key moments so far 🧡

03.02.2026 10:51 πŸ‘ 23 πŸ” 26 πŸ’¬ 1 πŸ“Œ 5
An imagine explaining that OpenAI is Trump's largest donor

An imagine explaining that OpenAI is Trump's largest donor

One more reason my soul shrivels up every time I hear someone say "I just used chatgpt to ____"

31.01.2026 17:32 πŸ‘ 7039 πŸ” 4326 πŸ’¬ 49 πŸ“Œ 75

That would be catastrophic

30.01.2026 08:20 πŸ‘ 17 πŸ” 5 πŸ’¬ 3 πŸ“Œ 0
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Sending babies to nursery completely reshapes their microbiomes Socializing at a young age helps to develop greater diversity in children’s microbiota, according to an analysis of baby-to-baby transmission of gut bacteria.

Sending babies to nursery completely reshapes their microbiomes.

Socializing at a young age helps to develop greater diversity in children’s microbiota, according to an analysis of baby-to-baby transmission of gut bacteria.

πŸ§ͺπŸ‘ΆπŸ¦  #medsky @medsky.social
www.nature.com/articles/d41...

23.01.2026 11:16 πŸ‘ 19 πŸ” 8 πŸ’¬ 1 πŸ“Œ 0

I agree, University education (like education in general) should be free. But at the very least student loans should be interest free until repaid in full...

23.01.2026 11:58 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
WHO graphic titled β€œMeasles can be fatal – Know the symptoms.” A child’s face and body are shown with red spots. Labels point to symptoms: rash starting on the face and spreading over the body, fever, red and watery eyes, runny nose, small white spots inside the cheeks, and cough.

WHO graphic titled β€œMeasles can be fatal – Know the symptoms.” A child’s face and body are shown with red spots. Labels point to symptoms: rash starting on the face and spreading over the body, fever, red and watery eyes, runny nose, small white spots inside the cheeks, and cough.

Measles can be fatal.

Do you know its symptoms?
πŸ”΄ Rash that starts on the face and spreads over the body
πŸ”΄ Fever
πŸ”΄ Cough
πŸ”΄ Red and watery eyes
πŸ”΄ Small white spots inside the cheeks

Seek health care if you suspect you or your child has measles. πŸ”—bit.ly/4iq4nkD

23.01.2026 11:47 πŸ‘ 216 πŸ” 98 πŸ’¬ 7 πŸ“Œ 15
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Osteoarthritis as a systemic disease Nature Reviews Rheumatology - Emerging evidence suggests a paradigm shift in viewing osteoarthritis (OA) as a systemic, bidirectional disease. This Review examines the current data supporting this...

Honored to share our new paper, Osteoarthritis as a Systemic Disease, in @natrevrheum.nature.com, out today: rdcu.be/eSXLW - thanks to Ida Haugen, @tuhinaneogi.bsky.social and @farsh-g.bsky.social for your input on gaps and opportunities.

03.12.2025 15:51 πŸ‘ 27 πŸ” 13 πŸ’¬ 0 πŸ“Œ 0

Unless the figure legend explains it well?

08.01.2026 12:07 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

I've no idea what I'm looking at πŸ˜…

08.01.2026 11:58 πŸ‘ 2 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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Merry Xmas everyone!!!

25.12.2025 07:58 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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I can't resist posting this picture of my beautiful 6 days-old angels 😍😍😍😍. Maternity life! Their first hug since being separated at birth for NICU treatment

15.08.2025 10:04 πŸ‘ 5 πŸ” 0 πŸ’¬ 3 πŸ“Œ 0
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I am very happy to announce that maternity has now officially started with the premature birth of my 2 beautiful girls. 😍😍😍😍😍😍😍😍😍😍

12.08.2025 03:47 πŸ‘ 3 πŸ” 0 πŸ’¬ 2 πŸ“Œ 0
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Complex regulatory interactions at GDF5 shape joint morphology and osteoarthritis disease risk Objectives To reveal causal level osteoarthritis (OA) disease biology by targeting regulatory interactions at GDF5. Methods By investigating different GDF5 regulatory regions (R2, R3-5, R7-R9, R18...

1) Despite the chaos, I am very pleased to present the terrific research conducted by my post-doc @clarissacoveney.bsky.social. acrjournals.onlinelibrary.wiley.com/doi/10.1002/...

21.05.2025 14:11 πŸ‘ 16 πŸ” 6 πŸ’¬ 1 πŸ“Œ 3
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On the responsibilities of intellectuals and the rise of bullshit jobs in universities You may never have considered yourself to be one. Why would you? But if you’re reading this, there is more than a likelihood that you are one. If you’re a

On the responsibilities of intellectuals and the rise of bullsh*t jobs in universities.

"Corporate academia is subverting academic life. It’s destroying academia from within."

πŸ§ͺπŸ‘©πŸΌβ€πŸŽ“

academic.oup.com/brain/articl...

14.03.2025 18:50 πŸ‘ 12 πŸ” 1 πŸ’¬ 0 πŸ“Œ 2
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Excited to share our work on the small but mighty microRNA-126-3p in @naturecomms.bsky.social! We found this microRNA is elevated in four knee osteoarthritis cohorts and show in an animal model that it reduces the severity of knee osteoarthritis - at least in part via angiogenesis. rdcu.be/ebycj

27.02.2025 19:23 πŸ‘ 14 πŸ” 4 πŸ’¬ 2 πŸ“Œ 2
β€’ Skills and learning. Universities in the UK play a crucial role in equipping graduates with high level skills. The UK is facing a shortage of 11 million graduates by 2035, when 88% of new jobs will be at graduate level.
β€’ Opportunity. The expansion of the higher education sector has afforded more people the opportunity to realise their ambitions, with 33% of the disadvantaged students progressing to university.
β€’ Economic growth. Higher education makes Β£130 billion contribution to the UK economy, supporting over 700,000 jobs in regions across the UK. R&D is one of the long-term
Registered Charity No. 233176
sources of UK competitive advantage and growth and every Β£1 invested in university research and innovation returns Β£10 for the UK economy.
Soft power. Over 50 world leaders received higher education in the UK and by educating large numbers of international students we develop our relationships around the world.

β€’ Skills and learning. Universities in the UK play a crucial role in equipping graduates with high level skills. The UK is facing a shortage of 11 million graduates by 2035, when 88% of new jobs will be at graduate level. β€’ Opportunity. The expansion of the higher education sector has afforded more people the opportunity to realise their ambitions, with 33% of the disadvantaged students progressing to university. β€’ Economic growth. Higher education makes Β£130 billion contribution to the UK economy, supporting over 700,000 jobs in regions across the UK. R&D is one of the long-term Registered Charity No. 233176 sources of UK competitive advantage and growth and every Β£1 invested in university research and innovation returns Β£10 for the UK economy. Soft power. Over 50 world leaders received higher education in the UK and by educating large numbers of international students we develop our relationships around the world.

In light of the major cutbacks at universities - especially in the arts, humanities and social sciences - we have written to the Chancellor to make the case for investing in research and higher education through the Spending Review
www.thebritishacademy.ac.uk/documents/56...

11.02.2025 08:43 πŸ‘ 43 πŸ” 23 πŸ’¬ 0 πŸ“Œ 1