Shweta Ramdas

@marcotrizzino.bsky.social @struangrant.bsky.social @tuuliel.bsky.social

This is akin to an upper level seminar course for students of biology or relevant fields. These videos can be watched in order or in isolation. Please do share widely. We will plan to update these with more videos on relevant topics periodically. 2/

Casey Brown Lecture Series - YouTube

Our mentor Casey Brown, apart from being an extraordinary scientist, was a brilliant teacher who loved everything genetics. In his honor, some of the world's leading experts came together to create the 'Casey Brown Lecture Series' on human genetics 1/ shorturl.at/eCm7S

Excited to share our latest work! We find that common-variant GWAS and rare-variant burden tests prioritize genes in fundamentally different ways, with important implications.

Check out Jeff’s excellent thread below👇

My mentor Casey Brown and I were talking about failed projects and I said how it was ok for projects in labs to fail. He interjected, "yes not every project has to succeed. But the every trainee of mine has to". The number of ways he has helped me start my career in India is impossible to list here.

Citrullinated and MMP-degraded vimentin is associated with chronic pulmonary diseases and genetic variants in PADI3/PADI4 and CFH in postmenopausal women - PubMed Citrullinated vimentin has been linked to several chronic and autoimmune diseases, but how citrullinated vimentin is associated with disease prevalence and genetic variants in a clinical setting remai...

Depending on how you count them there's something like 13000 unique traits in the @gwascatalog.bsky.social
Most new gwas add to our knowledge of these traits.

But some new gwas introduce new traits:

VICM = citrullonated and MMP degraded vimentin, a biomarker

pubmed.ncbi.nlm.nih.gov/38155185/