New publication out today from the amazing PhD dissertation of Karen Konkoly @karenkonkoly.bsky.social in Neuroscience of Consciousness @nconsc.bsky.social : Creative problem-solving after experimentally provoking dreams of unsolved puzzles during REM sleep academic.oup.com/nc/article/2...
Using the INSIGHT-preAD cohort, we showed that in older adults with subjective cognitive decline, resting-state wake slow wave patterns:
-Differ by amyloid/neurodegeneration (A/N) status
-Correlate with cognition
-Predict amyloid positivity (A+) conversion within 2 years
Happy to share new preprint on wake slow waves in older adults with subjective cognitive decline, with my awesome postdoc mentors @thomasandrillon.bsky.social & @oudietted.bsky.social at @institutducerveau.bsky.social
Thanks @alzheimer-recherche.org for support!
www.medrxiv.org/content/10.6...
Evolutionary insights into sleep infraslow rhythmicity! Excited to see research investigating such rhythms beyond humans and rodent models, including pigeons π¦ and 7 lizard species π¦
Sleep pressure and slow-wave-rich NREM sleep exert distinct effects on cerebral vasomotion and on brain pulsations driven by respiratory and cardiac forces. Heightened sleep pressure (following 35βh of wakefulness) promotes vasomotion (yellow box). Slow-wave-rich NREM sleep enhances brain pulsations driven by the respiratory and cardiac cyclesβmore so in gray and white matter than in the ventricles (red boxes). The respiration- and cardiac-driven brain pulsations also intensify with deeper sleep (N3β>βN2) and correlate with EEG delta power, which is a measure of slow-wave activity (light vs. dark red boxes).
Sleep supports brain health partly by regulating fluid dynamics to clear waste. @ulvlarsen.bsky.social &co probe the relation between #sleep & fluid movement in the human #brain, finding that #SleepPressure & intensity have distinct effects on brain pulsations @plosbiology.org π§ͺ plos.io/3XQWCL6
Announcing the 5th International Sleep Replay Workshop (ISRW): March 6, 2026, Vancouver, prior to CNS.
Program: poster session, discussion groups, 2 symposia, 7 short talks, & many opportunities to interact.
Register by Dec 19 at isrw.bio.uci.edu
All researchers focused on sleep/cognition welcome.
#CNS2026 | Satellite - International Sleep Replay Workshop
Friday, March 6, 2026, 8:00 am - 6:00 pm, Salon F
The workshop is open to all: experience with sleep research is not required. Register here: isrw.bio.uci.edu Registration Deadline, February 15th
@cogneuronews.bsky.social #SleepRelay
International recommendations for sleep and circadian research in aging and Alzheimer's disease: A Delphi consensus study
alz-journals.onlinelibrary.wiley.com/doi/10.1002/...
Our paper on CSF, BOLD, pupil, and physiological measures in sleep deprivation and recovery sleep is finally out! π Congrats Zinong! www.nature.com/articles/s41...
Amazing new study combining functional PET(fPET)-FDG and EEG-fMRI simultaneously during wakefulness and sleep, providing both temporal and spatial insights into metabolic and hemodynamic activities at the infraslow scale (~0.02 Hz) during NREM sleep. Wow π€―
www.nature.com/articles/s41...
Neuroscience of Dreaming Summer School
Neuroscience of Dreaming
Summer School - May 4-8, 2026 - Lucca, Italy
Applications open: nodsummerschool.imtlucca.it
Check out our new preprint:
www.biorxiv.org/content/10.1...
And Paris' thread (@parboulakis.bsky.social):
bsky.app/profile/parb...
Where we explore the neural signature of mind blanking using EEG and fMRI combined!
1/ "Hemispherotomy leads to persistent sleep-like slow waves in the isolated cortex of awake humans" - out now in @plosbiology.org, led by Michele Colombo, Jacopo Favaro, & Marcello Massimini. π§
Please RT! ππποΏΌ
1/3 How do you correct for multiple comparisons? Do you take into account *all* comparisons that can render the paper publishable? Most of us donβt. In this NHB piece, Yoav Benjamini, Yoav Zeevi and I argue that itβs time to change our practices >>
www.nature.com/articles/s41...
Kort Driessen, Fabio Squarcio, Giulio Tononi, Chiara Cirelli
"Induction of cortical ON/OFF periods in awake mice fulfills sleep functions"
doi.org/10.1101/2025...
New paper! π§ π€
www.nature.com/articles/s41...
Led by Pauline Dodet - @dreamteamicm.bsky.social
We show that #sleep stage mixing predicts poor prognosis in #Parkinson.
Stage mixing = intrusions of wake-like activity during sleep, and vice versa. Estimated with hypnodensities extracted from PSG.
17,058 proposals received, 1,650 to be funded.
Break-even, where more money is paid out than burned by the process, is ~2 months time investment per application (assuming only few admin/review/non-submitted efforts).
Uncomfortably close to predatory territory: doi.org/10.1111/imcb...
Preprint on sleep-like slow waves during wakefulness in Parkinson's disease
Inspiring preprint on delta waves in REM (yes, REM) sleep in the context of ageing and Alzheimer's disease, great work!
New paper in Imaging Neuroscience by Martyna Rakowska, Penelope A. Lewis, et al:
Distributed and gradual microstructure changes are associated with the emergence of behavioural benefit from memory reactivation
doi.org/10.1162/IMAG...
π Honored and grateful to the Neurophysiology PIA for awarding me the ππ¨π¬πππ¨πππ¨π«ππ₯ πππ¬π ππ¨π¬πππ« prize at AAIC (worldβs largest research conference on Alzheimerβs disease and dementia) for my work on EEG wake slow waves in older adults π§ Thanks to all collaborators at ICM!
@alzassociation.bsky.social
Illustration from Ana Yael https://www.anayael.com/
π€π§ π§ͺ New article! π§ͺπ§ π€
After years of effort led by @qualiastructure.bsky.social (Nao Tsuchiya and William Wong), Jenny Windt, Katja Valli, Valdas Noreika and @rherzoga.bsky.social, the Dream database is now published in @natcomms.nature.com
**A dream EEG and mentation database**
rdcu.be/eAwni
Interesting study showing that stress shortens REM sleep through an action of the PFC π§ π€
www.cell.com/current-biol...
π Thrilled to share the last paper of my PhD in J.Sleep Res., in which we delved into wake and sleep of expert meditators (>10,000 lifetime hoursπ§ββοΈ), notably assessing EEG power, complexity, SW and spindles! Thanks @neuropresage.bsky.social
@esrs.bsky.social
onlinelibrary.wiley.com/doi/10.1111/...
Interesting work on local sleep in ADHD! π€
Congrats Elaine, @thomasandrillon.bsky.social and co-authors!
Happy to present an online poster at the #AAIC2025, entitled "Wake slow waves during resting-state EEG vary with current and two-year changes in amyloid and neurodegeneration status in older adults with memory complaints". Don't hesitate to contact me on the AAIC platform π
If you are in Paris on October 1-3 : we are organizing a fantastic cognitive neuroscience conference at Collège de France, on topics ranging from language to math, education and consciousness, with many of my favorite scientists !
Full program here:
www.unicog.org/seeing-the-m...
Very interesting preprint linking EEG slowing during REM sleep and in vivo cholinergic denervation in the elderly!
π₯π Over 1,000 neuroscience talks now free on YouTube and published at @apertureohbm.bsky.social. π§ βNow anyone, anywhere can binge-watch brain science like a box set,β says @stephforkel.bsky.social:
www.ru.nl/en/donders-i...
@alfiewearn.bsky.social @sitek.bsky.social @sofievalk.bsky.social
Nice paper on a new kind of brain rhythm in wake and REM sleep: iota oscillations (25β35 Hz) π€―Interesting insight into fast activity beyond traditional bands, eager to know what is the cognitive relevance of this rhythm!
