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Scott Nichols

@scottnichols

Associate Professor of Biology @ University of Denver. Sponges, evolution, cell biology.

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05.08.2023
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Latest posts by Scott Nichols @scottnichols

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An unconventional Rubisco small subunit underpins the CO2-concentrating organelle in land plants In many algae, photosynthesis is boosted by biophysical CO2-concentrating mechanisms, which pack the CO2-fixing enzyme Rubisco into liquid-like organelles called pyrenoids. Engineering C3 crops with a...

Our work on #hornwort #pyrenoids is finally out in @science.org! πŸŽ‰ We uncovered how hornworts pack their Rubisco into pyrenoids and successfully recreated them in Arabidopsis. A key step toward engineering more efficient photosynthesis in crops @btiscience.bsky.social www.science.org/doi/10.1126/...

05.03.2026 20:03 πŸ‘ 124 πŸ” 63 πŸ’¬ 6 πŸ“Œ 7

Thrilled to share that our preprint has been accepted in Science Advances! Grateful to an incredible team & collaborators.

Link: www.science.org/doi/10.1126/...

πŸ‘ @annaferraioli.bsky.social @maikekittelmann.bsky.social
@msarscentre.bsky.social @erc.europa.eu @hfspo.bsky.social #ctenophores

04.03.2026 20:49 πŸ‘ 65 πŸ” 16 πŸ’¬ 2 πŸ“Œ 2
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A 2000 year old barrel sponges in the Banda Sea spawn with the full moon, a rare natural spectacle of life. Found throughout the Β 
tropicalΒ coral reef environments inΒ the Atlantic Ocean,Β these sponges grow slowly but can live for centuries or thousands of years in

02.03.2026 21:14 πŸ‘ 507 πŸ” 116 πŸ’¬ 16 πŸ“Œ 7

Final version @nature.com of our paper describing unconventional multicellular development in a choanoflagellate inhabiting an extreme environment. A ton of new data since the first @biorxivpreprint.bsky.social preprint (which we've kept updating).

A brief 🧡 (carried over from the old place)

28.02.2026 08:12 πŸ‘ 362 πŸ” 147 πŸ’¬ 16 πŸ“Œ 16
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Two funded PhD positions investigating the evolution of sarcomeres @ibdm.bsky.social in @biancah0406.bsky.social and our lab, together with @cnidevo.bsky.social - Interested to explore how similar or different Jellyfish sarcomeres are to Drosophila or human ones?
www.ibdm.univ-amu.fr/ibdm_job/2-a...

16.02.2026 10:49 πŸ‘ 45 πŸ” 35 πŸ’¬ 1 πŸ“Œ 1
Evolution of monoamine reception and its role in cellular contractility.

Evolution of monoamine reception and its role in cellular contractility.

How do #sponges coordinate their bodies despite lacking neurons and true muscles?

We show that sponges use monoamines to control water flow in their canals β€” reminiscent of how adrenaline regulates blood vessels.

My PhD story, now on BioRxiv:
www.biorxiv.org/content/10.6...
#Evolution

18.02.2026 13:34 πŸ‘ 62 πŸ” 21 πŸ’¬ 3 πŸ“Œ 4
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Neural connectome of the ctenophore statocyst Volume EM and connectome reconstruction of the apical organ of a ctenophore combined with high-speed imaging reveals a neuronal coordination of balancer cilia in the gravisensory organ.

In @eLife: Neural connectome of the ctenophore statocyst https://doi.org/10.7554/eLife.108420
Version of record of our ctenophore nerve-net connectome paper.

18.02.2026 10:30 πŸ‘ 37 πŸ” 15 πŸ’¬ 2 πŸ“Œ 0
Santa Cruz Developmental Biology Meeting

Registration is OPEN for the 2026 Santa Cruz Meeting on Developmental Biology!!! Please spread the word!

@mads100tist.bsky.social @socdevbio.bsky.social @bsdb.bsky.social @xenbase.bsky.social @isdb.bsky.social @devbiol.bsky.social @the-node.bsky.social

scdb2026.sites.ucsc.edu

10.02.2026 20:12 πŸ‘ 46 πŸ” 39 πŸ’¬ 1 πŸ“Œ 4
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Congratulations to @arnausebe.bsky.social, Premi Ciutat de Barcelona 2025 in the category of Life Sciences and Medicine. The award ceremony will take place today at the historic SalΓ³ de Cent and was presided over by the Mayor of Barcelona. Full story: www.crg.eu/en/news/arna...

11.02.2026 07:52 πŸ‘ 20 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0

Excited to announce a new preprint from my PhD student @pawley.bsky.social :

"The discovery of an external bacterial niche reconciles sequencing-based microbiomes in a freshwater sponge."

10.02.2026 00:09 πŸ‘ 4 πŸ” 0 πŸ’¬ 0 πŸ“Œ 1

He’s also hilarious. I wish he was mic’d up every game

30.01.2026 03:05 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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What were the first animals? The fierce sponge–jelly battle that just won’t end For almost two decades, scientists have debated whether sponges or comb jellies are the first animal lineage. Now some are calling for a more harmonious approach.

The last word on Ctenophores versus Sponges (not).
www.nature.com/articles/d41...

27.01.2026 13:19 πŸ‘ 27 πŸ” 11 πŸ’¬ 1 πŸ“Œ 2

❀️‍πŸ”₯

22.01.2026 02:40 πŸ‘ 383 πŸ” 96 πŸ’¬ 3 πŸ“Œ 0
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Mystery of the Head Activator A biological puzzle that made one researcher and ruined another might never be solved.

press.asimov.com/articles/hea...

15.01.2026 18:51 πŸ‘ 6 πŸ” 2 πŸ’¬ 0 πŸ“Œ 1
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Seeing this video of two Great Horned owls (Bubo virginianus) from Colton Lockridge you might think:
"Get a room, you two."

But, uh... these are juvenile siblings. 🀨

The behavior shown here is called 'billing' or 'bill fencing' & it's a playful social interaction, *no matter what it looks like*.

15.01.2026 13:49 πŸ‘ 106 πŸ” 21 πŸ’¬ 4 πŸ“Œ 0
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1/3 Jellyfish and anemones also sleep, despite not having a brain

Not only do they sleep, but their behavior is affected if they lack sleep; they become clumsier and need to catch up on lost sleep. Interestingly, they sleep 8 hours a day, just like us.

(paper) www.nature.com/articles/s41...

14.01.2026 11:32 πŸ‘ 123 πŸ” 52 πŸ’¬ 4 πŸ“Œ 4
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A giant virus forms a specialized subcellular environment within its amoeba host for efficient translation www.nature.com/articles/s41...

12.01.2026 09:10 πŸ‘ 16 πŸ” 6 πŸ’¬ 1 πŸ“Œ 0

I saw one of these last week for the first time, in San Diego. What a coincidence to see, it mentioned in my bluesky timeline! It had a barnacle on one end, and red algae growing off of that like a ribbon streamer

10.01.2026 19:53 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Our eLetter github.com/caseywdunn/s... responding to a recent Science paper was just posted. The paper found more genes with consistent support for sponge-sister than ctenophore-sister. We found several technical issues that, when corrected, reverse the conclusions and recover ctenophore-sister.

09.01.2026 11:44 πŸ‘ 131 πŸ” 57 πŸ’¬ 5 πŸ“Œ 9
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Independent origins of spicules reconcile paleontological and molecular evidence of sponge evolutionary history Sponges have a cryptic Ediacaran history because ancestral sponges were soft-bodied and had low fossilization potential.

Our latest: Independent origins of spicules reconcile paleontological and molecular evidence of sponge evolutionary history, led by @meleonora-rossi.bsky.social with help from friends @bristolpalaeo.bsky.social including @anariesgo.bsky.social @evopalaeo.bsky.social Davide Pisani and many others

08.01.2026 07:39 πŸ‘ 68 πŸ” 25 πŸ’¬ 1 πŸ“Œ 2
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Tectura paleacea … surfgrass limpet. Only grows as wide as the seagrass blade it lives on.

04.01.2026 01:16 πŸ‘ 4 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Help with invert ID? Point lobos, Carmel CA. I don’t know what either the yellow or the while things are. White looks like it has two siphons, yellow has only one. Thinking the yellow might be a keyhole limpet? No idea about the white one….

31.12.2025 18:22 πŸ‘ 2 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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It’s publication day! β€œTeaching and Mentoring Writers in the Sciences” Ok, we’re seriously excited – not for tonight’s fireworks, but because after several years of work, our new book is officially published today! That’s right – Teaching and Mentoring Writers i…

It's official - my new book is officially published today! If you mentor science students who write - grad or undergrad - you're the reason we wrote this. Mentoring/teaching writing is hard; but we can make it easier!

31.12.2025 13:18 πŸ‘ 68 πŸ” 23 πŸ’¬ 4 πŸ“Œ 0
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Finally, we’ve solved a long-standing mystery: what tintinnid shells are actually made of:
A new class of biomaterial formed by remarkable structural proteins unique to tintinnids.
A major milestone after 3 years of work! Read about it in our preprint: doi.org/10.64898/202...
#ProtistsOnSky

27.12.2025 10:30 πŸ‘ 95 πŸ” 35 πŸ’¬ 4 πŸ“Œ 3
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β€˜The Tree of Life’ Review: The Ancestor at the Root of It All Properly deciphering the branching pathways of evolution could unlock the history of every component of natural biology.

My review of Max Telford’s excellent new book β€˜The Tree of Life’ by @maxjtelford.bsky.social published today in the Wall Street Journal @wsj.com @wwnorton.com

www.wsj.com/arts-culture...

27.12.2025 01:39 πŸ‘ 4 πŸ” 2 πŸ’¬ 0 πŸ“Œ 2
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Charting the landscape of cytoskeletal diversity in microbial eukaryotes An imaging resource of over 200 microbial eukaryotic species provides a glimpse into the remarkable universe of cytoskeletal diversity.

Tour de force #UExM study of #protist #cytoskeleton structures (>200 species🀯), led by @dudinlab.bsky.social, @gautamdey.bsky.social. A must for #tubulin & #centrin aficionados🀩
www.cell.com/cell/fulltex...

25.12.2025 17:11 πŸ‘ 23 πŸ” 7 πŸ’¬ 2 πŸ“Œ 0
P. tenue, its symbionts, and natural habitat

P. tenue, its symbionts, and natural habitat

End-of-year preprint dump! A collaboration with @messorensen.bsky.social and German and Korean colleagues: "The phylogenetic context for the origin of a unique purple-green photosymbiosis "
doi.org/10.64898/202...

23.12.2025 14:51 πŸ‘ 74 πŸ” 27 πŸ’¬ 2 πŸ“Œ 3
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🚨 POSTDOC OPENING 🚨
NIH-funded Bio-Fluid Mechanics Postdoc in my lab @univmiami.bsky.social
Hofstenia miamia | cilia-driven flows | behavior & neuroscience
Collab w/ Mansi Srivastava @harvard.edu
πŸ•’ Start: Jan–Feb 2026
⏳ 1 yr, renewable | Email me ASAP!
#Postdoc #Biophysics #FluidDynamics

23.12.2025 18:31 πŸ‘ 30 πŸ” 27 πŸ’¬ 0 πŸ“Œ 1
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Decoding cnidarian cell type gene regulation - Nature Ecology & Evolution This study reconstructs the gene regulatory networks that define cell types in the sea anemone Nematostella vectensis, providing a valuable resource for comparative regulatory genomics and the evoluti...

Excited to share the final version of our study on Nematostella cell type regulatory programs. Part of our @erc.europa.eu StG project, this was a challenging 5-year effort extraodinarily led by @aelek.bsky.social and @martaig.bsky.social.

www.nature.com/articles/s41...

22.12.2025 10:12 πŸ‘ 107 πŸ” 37 πŸ’¬ 8 πŸ“Œ 3